| Wound‐healing factors secreted by epidermal keratinocytes and dermal fibroblasts in skin substitutes SW Spiekstra, M Breetveld, T Rustemeyer, RJ Scheper, S Gibbs Wound Repair and Regeneration 15 (5), 708-717, 2007 | 204 | 2007 |
| Induction of cytokine (interleukin‐1α and tumor necrosis factor‐α) and chemokine (CCL20, CCL27, and CXCL8) alarm signals after allergen and irritant exposure SW Spiekstra, MJ Toebak, S Sampat‐Sardjoepersad, PJ Van Beek, ... Experimental Dermatology 14 (2), 109-116, 2005 | 146 | 2005 |
| Autologous full‐thickness skin substitute for healing chronic wounds S Gibbs, HM Van Den Hoogenband, G Kirtschig, CD Richters, ... British Journal of Dermatology 155 (2), 267-274, 2006 | 138 | 2006 |
| An epidermal equivalent assay for identification and ranking potency of contact sensitizers S Gibbs, E Corsini, SW Spiekstra, V Galbiati, HW Fuchs, G DeGeorge, ... Toxicology and applied pharmacology 272 (2), 529-541, 2013 | 135 | 2013 |
| Technical advance: Langerhans cells derived from a human cell line in a full-thickness skin equivalent undergo allergen-induced maturation and migration K Ouwehand, SW Spiekstra, T Waaijman, RJ Scheper, TD de Gruijl, ... Journal of leukocyte biology 90 (5), 1027-1033, 2011 | 120 | 2011 |
| Assessment of preferential T-helper 1 or T-helper 2 induction by low molecular weight compounds using the local lymph node assay in conjunction with RT-PCR and ELISA for … RJ Vandebriel, WH De Jong, SW Spiekstra, M Van Dijk, A Fluitman, ... Toxicology and applied pharmacology 162 (2), 77-85, 2000 | 108 | 2000 |
| Cytokines at different stratum corneum levels in normal and sodium lauryl sulphate‐irritated skin CM De Jongh, MM Verberk, SW Spiekstra, S Gibbs, S Kezic Skin Research and Technology 13 (4), 390-398, 2007 | 90 | 2007 |
| MUTZ-3 derived Langerhans cells in human skin equivalents show differential migration and phenotypic plasticity after allergen or irritant exposure IJ Kosten, SW Spiekstra, TD de Gruijl, S Gibbs Toxicology and Applied Pharmacology 287 (1), 35-42, 2015 | 88 | 2015 |
| Development of a full-thickness human gingiva equivalent constructed from immortalized keratinocytes and fibroblasts JK Buskermolen, CMA Reijnders, SW Spiekstra, T Steinberg, ... Tissue Engineering Part C: Methods 22 (8), 781-791, 2016 | 78 | 2016 |
| Ranking of allergenic potency of rubber chemicals in a modified local lymph node assay WH De Jong, FMM Van Och, CF Den Hartog Jager, SW Spiekstra, W Slob, ... Toxicological sciences 66 (2), 226-232, 2002 | 68 | 2002 |
| A potential in vitro epidermal equivalent assay to determine sensitizer potency GG dos Santos, SW Spiekstra, SC Sampat-Sardjoepersad, J Reinders, ... Toxicology in vitro 25 (1), 347-357, 2011 | 65 | 2011 |
| Cytokine and chemokine release upon prolonged mechanical loading of the epidermis D Bronneberg, SW Spiekstra, LH Cornelissen, CWJ Oomens, S Gibbs, ... Experimental dermatology 16 (7), 567-573, 2007 | 65 | 2007 |
| Gingiva equivalents secrete negligible amounts of key chemokines involved in langerhans cell migration compared to skin equivalents IJ Kosten, JK Buskermolen, SW Spiekstra, TD de Gruijl, S Gibbs Journal of immunology research 2015, 2015 | 61 | 2015 |
| Comparison of a novel CXCL12/CCL5 dependent migration assay with CXCL8 secretion and CD86 expression for distinguishing sensitizers from non-sensitizers using MUTZ-3 Langerhans … K Ouwehand, SW Spiekstra, J Reinders, RJ Scheper, TD de Gruijl, ... Toxicology in Vitro 24 (2), 578-585, 2010 | 60 | 2010 |
| Potential method to determine irritant potency in vitro–Comparison of two reconstructed epidermal culture models with different barrier competency SW Spiekstra, GG Dos Santos, RJ Scheper, S Gibbs Toxicology in Vitro 23 (2), 349-355, 2009 | 53 | 2009 |
| Immune-competent human skin disease models LIJC Bergers, CMA Reijnders, LJ van den Broek, SW Spiekstra, ... Drug discovery today 21 (9), 1479-1488, 2016 | 51 | 2016 |
| Transfer of a two-tiered keratinocyte assay: IL-18 production by NCTC2544 to determine the skin sensitizing capacity and epidermal equivalent assay to determine sensitizer potency M Teunis, E Corsini, M Smits, CB Madsen, T Eltze, J Ezendam, V Galbiati, ... Toxicology in Vitro 27 (3), 1135-1150, 2013 | 49 | 2013 |
| CCL5 and CCL20 mediate immigration of Langerhans cells into the epidermis of full thickness human skin equivalents K Ouwehand, SW Spiekstra, T Waaijman, M Breetveld, RJ Scheper, ... European Journal of Cell Biology 91 (10), 765-773, 2012 | 44 | 2012 |
| Determination of the sensitising activity of the rubber contact sensitisers TMTD, ZDMC, MBT and DEA in a modified local lymph node assay and the effect of sodium dodecyl … WH De Jong, M Tentij, SW Spiekstra, RJ Vandebriel, H Van Loveren Toxicology 176 (1-2), 123-134, 2002 | 42 | 2002 |
| Comparison of the skin sensitization potential of 3 red and 2 black tattoo inks using interleukin‐18 as a biomarker in a reconstructed human skin model W Bil, SAS van der Bent, SW Spiekstra, K Nazmi, T Rustemeyer, S Gibbs Contact Dermatitis 79 (6), 336-345, 2018 | 40 | 2018 |
Tanja D. de GruijlProfessor Translational Tumor Immunology, Amsterdam UMC, Vrije Universiteit, AmsterdamAdresse e-mail validée de vumc.nl
