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Emanuela Maria Ghia
Emanuela Maria Ghia
UCSD Moores Cancer Center
Geverifieerd e-mailadres voor ucsd.edu
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Prolonged lymphocytosis during ibrutinib therapy is associated with distinct molecular characteristics and does not indicate a suboptimal response to therapy
JA Woyach, K Smucker, LL Smith, A Lozanski, Y Zhong, AS Ruppert, ...
Blood, The Journal of the American Society of Hematology 123 (12), 1810-1817, 2014
3382014
MicroRNA-155 influences B-cell receptor signaling and associates with aggressive disease in chronic lymphocytic leukemia
B Cui, L Chen, S Zhang, M Mraz, JF Fecteau, J Yu, EM Ghia, L Zhang, ...
Blood, The Journal of the American Society of Hematology 124 (4), 546-554, 2014
2412014
Transcriptome Sequencing Reveals Potential Mechanism of Cryptic 3’ Splice Site Selection in SF3B1-mutated Cancers
C DeBoever, EM Ghia, PJ Shepard, L Rassenti, CL Barrett, K Jepsen, ...
PLoS computational biology 11 (3), e1004105, 2015
2262015
Immunohistochemistry predicts nucleophosmin (NPM) mutations in acute myeloid leukemia
B Falini, MP Martelli, N Bolli, R Bonasso, E Ghia, MT Pallotta, D Diverio, ...
Blood 108 (6), 1999-2005, 2006
2192006
Transcriptomic characterization of SF3B1 mutation reveals its pleiotropic effects in chronic lymphocytic leukemia
L Wang, AN Brooks, J Fan, Y Wan, R Gambe, S Li, S Hergert, S Yin, ...
Cancer cell 30 (5), 750-763, 2016
2092016
Ovarian cancer stem cells express ROR1, which can be targeted for anti–cancer-stem-cell therapy
S Zhang, B Cui, H Lai, G Liu, EM Ghia, GF Widhopf, Z Zhang, CCN Wu, ...
Proceedings of the National Academy of Sciences 111 (48), 17266-17271, 2014
1902014
miR-150 influences B-cell receptor signaling in chronic lymphocytic leukemia by regulating expression of GAB1 and FOXP1
M Mraz, L Chen, LZ Rassenti, EM Ghia, H Li, K Jepsen, EN Smith, ...
Blood, The Journal of the American Society of Hematology 124 (1), 84-95, 2014
1752014
Phase I trial: cirmtuzumab inhibits ROR1 signaling and stemness signatures in patients with chronic lymphocytic leukemia
MY Choi, GF Widhopf, EM Ghia, RL Kidwell, MK Hasan, J Yu, LZ Rassenti, ...
Cell Stem Cell 22 (6), 951-959. e3, 2018
1432018
High-level ROR1 associates with accelerated disease progression in chronic lymphocytic leukemia
B Cui, EM Ghia, L Chen, LZ Rassenti, C DeBoever, GF Widhopf, J Yu, ...
Blood, The Journal of the American Society of Hematology 128 (25), 2931-2940, 2016
1342016
The Dohner fluorescence in situ hybridization prognostic classification of chronic lymphocytic leukaemia (CLL): the CLL Research Consortium experience
DL Van Dyke, L Werner, LZ Rassenti, D Neuberg, E Ghia, NA Heerema, ...
British journal of haematology 173 (1), 105-113, 2016
1102016
Inhibition of chemotherapy resistant breast cancer stem cells by a ROR1 specific antibody
S Zhang, H Zhang, EM Ghia, J Huang, L Wu, J Zhang, S Lam, Y Lei, J He, ...
Proceedings of the National Academy of Sciences 116 (4), 1370-1377, 2019
1092019
ROR1 can interact with TCL1 and enhance leukemogenesis in Eµ-TCL1 transgenic mice
GF Widhopf, B Cui, EM Ghia, L Chen, K Messer, Z Shen, SP Briggs, ...
Proceedings of the National Academy of Sciences 111 (2), 793-798, 2014
1072014
Lenalidomide inhibits the proliferation of CLL cells via a cereblon/p21WAF1/Cip1-dependent mechanism independent of functional p53
JF Fecteau, LG Corral, EM Ghia, S Gaidarova, D Futalan, IS Bharati, ...
Blood, The Journal of the American Society of Hematology 124 (10), 1637-1644, 2014
1042014
Targeting the spliceosome in chronic lymphocytic leukemia with the macrolides FD-895 and pladienolide-B
MK Kashyap, D Kumar, R Villa, JJ La Clair, C Benner, R Sasik, H Jones, ...
Haematologica 100 (7), 945, 2015
942015
Use of IGHV3–21 in chronic lymphocytic leukemia is associated with high-risk disease and reflects antigen-driven, post–germinal center leukemogenic selection
EM Ghia, S Jain, GF Widhopf, LZ Rassenti, MJ Keating, WG Wierda, ...
Blood, The Journal of the American Society of Hematology 111 (10), 5101-5108, 2008
932008
A murine model of chronic lymphocytic leukemia based on B cell-restricted expression of Sf3b1 mutation and Atm deletion
S Yin, RG Gambe, J Sun, AZ Martinez, ZJ Cartun, FFD Regis, Y Wan, ...
Cancer Cell 35 (2), 283-296. e5, 2019
922019
Comprehensive characterization of IGHV3-21–expressing B-cell chronic lymphocytic leukemia: an Italian multicenter study
R Bomben, M Dal Bo, D Capello, D Benedetti, D Marconi, A Zucchetto, ...
Blood 109 (7), 2989-2998, 2007
872007
Recombinant antibodies encoded by IGHV1-69 react with pUL32, a phosphoprotein of cytomegalovirus and B-cell superantigen
C Steininger, GF Widhopf, EM Ghia, CS Morello, K Vanura, R Sanders, ...
Blood, The Journal of the American Society of Hematology 119 (10), 2293-2301, 2012
842012
Dielectrophoretic isolation and detection of cancer‐related circulating cell‐free DNA biomarkers from blood and plasma
A Sonnenberg, JY Marciniak, EA Skowronski, S Manouchehri, L Rassenti, ...
Electrophoresis 35 (12-13), 1828-1836, 2014
772014
Rapid electrokinetic isolation of cancer-related circulating cell-free DNA directly from blood
A Sonnenberg, JY Marciniak, L Rassenti, EM Ghia, EA Skowronski, ...
Clinical chemistry 60 (3), 500-509, 2014
722014
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Artikelen 1–20