| IL-6R/STAT3/miR-34a feedback loop promotes EMT-mediated colorectal cancer invasion and metastasis M Rokavec, MG Öner, H Li, R Jackstadt, L Jiang, D Lodygin, M Kaller, ... The Journal of clinical investigation 124 (4), 1853-1867, 2014 | 774 | 2014 |
| miR-34 and SNAIL form a double-negative feedback loop to regulate epithelial-mesenchymal transitions H Siemens, R Jackstadt, S Hünten, M Kaller, A Menssen, U Götz, ... Cell cycle 10 (24), 4256-4271, 2011 | 693 | 2011 |
| Epithelial NOTCH signaling rewires the tumor microenvironment of colorectal cancer to drive poor-prognosis subtypes and metastasis R Jackstadt, SR van Hooff, JD Leach, X Cortes-Lavaud, JO Lohuis, ... Cancer cell 36 (3), 319-336. e7, 2019 | 305 | 2019 |
| Single-cell analysis defines a pancreatic fibroblast lineage that supports anti-tumor immunity C Hutton, F Heider, A Blanco-Gomez, A Banyard, A Kononov, X Zhang, ... Cancer cell 39 (9), 1227-1244. e20, 2021 | 192 | 2021 |
| Detection of miR-34a Promoter Methylation in Combination with Elevated Expression of c-Met and β-Catenin Predicts Distant Metastasis of Colon Cancer H Siemens, J Neumann, R Jackstadt, U Mansmann, D Horst, T Kirchner, ... Clinical cancer research 19 (3), 710-720, 2013 | 180 | 2013 |
| SNAIL and miR‐34a feed‐forward regulation of ZNF281/ZBP99 promotes epithelial–mesenchymal transition S Hahn, R Jackstadt, H Siemens, S Hünten, H Hermeking The EMBO journal 32 (23), 3079-3095, 2013 | 177 | 2013 |
| Repression of c-Kit by p53 is mediated by miR-34 and is associated with reduced chemoresistance, migration and stemness H Siemens, R Jackstadt, M Kaller, H Hermeking Oncotarget 4 (9), 1399, 2013 | 167 | 2013 |
| AP4 is a mediator of epithelial–mesenchymal transition and metastasis in colorectal cancer R Jackstadt, S Röh, J Neumann, P Jung, R Hoffmann, D Horst, C Berens, ... Journal of Experimental Medicine 210 (7), 1331-1350, 2013 | 163 | 2013 |
| p53-induced miR-15a/16-1 and AP4 form a double-negative feedback loop to regulate epithelial–mesenchymal transition and metastasis in colorectal cancer L Shi, R Jackstadt, H Siemens, H Li, T Kirchner, H Hermeking Cancer research 74 (2), 532-542, 2014 | 149 | 2014 |
| Tissue-specific opposing functions of the inflammasome adaptor ASC in the regulation of epithelial skin carcinogenesis SK Drexler, L Bonsignore, M Masin, A Tardivel, R Jackstadt, H Hermeking, ... Proceedings of the National Academy of Sciences 109 (45), 18384-18389, 2012 | 146 | 2012 |
| The amino acid transporter SLC7A5 is required for efficient growth of KRAS-mutant colorectal cancer AK Najumudeen, F Ceteci, SK Fey, G Hamm, RT Steven, H Hall, ... Nature genetics 53 (1), 16-26, 2021 | 139 | 2021 |
| Mouse models of intestinal cancer R Jackstadt, OJ Sansom The Journal of pathology 238 (2), 141-151, 2016 | 138 | 2016 |
| MicroRNAs as regulators and mediators of c-MYC function R Jackstadt, H Hermeking Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1849 (5), 544-553, 2015 | 121 | 2015 |
| A MYC–GCN2–eIF2α negative feedback loop limits protein synthesis to prevent MYC-dependent apoptosis in colorectal cancer S Schmidt, D Gay, FW Uthe, S Denk, M Paauwe, N Matthes, ... Nature cell biology 21 (11), 1413-1424, 2019 | 82 | 2019 |
| Loss of BCL9/9l suppresses Wnt driven tumourigenesis in models that recapitulate human cancer DM Gay, RA Ridgway, M Müller, MC Hodder, A Hedley, W Clark, ... Nature communications 10 (1), 723, 2019 | 80 | 2019 |
| Suppression of tumor-associated neutrophils by lorlatinib attenuates pancreatic cancer growth and improves treatment with immune checkpoint blockade SR Nielsen, JE Strøbech, ER Horton, R Jackstadt, A Laitala, MC Bravo, ... Nature Communications 12 (1), 3414, 2021 | 69 | 2021 |
| Expression, cellular distribution, and prognostic relevance of TRAIL receptors in hepatocellular carcinoma L Kriegl, A Jung, J Engel, R Jackstadt, AL Gerbes, E Gallmeier, JA Reiche, ... Clinical cancer research 16 (22), 5529-5538, 2010 | 58 | 2010 |
| MNK Inhibition Sensitizes KRAS-Mutant Colorectal Cancer to mTORC1 Inhibition by Reducing eIF4E Phosphorylation and c-MYC Expression JRP Knight, C Alexandrou, GL Skalka, N Vlahov, K Pennel, L Officer, ... Cancer discovery 11 (5), 1228-1247, 2021 | 53 | 2021 |
| WNT and β-Catenin in Cancer: Genes and Therapy R Jackstadt, MC Hodder, OJ Sansom Annual Review of Cancer Biology 4, 177-196, 2020 | 51 | 2020 |
| Desmogleins as prognostic biomarkers in resected pancreatic ductal adenocarcinoma S Ormanns, A Altendorf-Hofmann, R Jackstadt, D Horst, G Assmann, ... British journal of cancer 113 (10), 1460-1466, 2015 | 46 | 2015 |
