| Human embryonic stem cell-derived test systems for developmental neurotoxicity: a transcriptomics approach AK Krug, R Kolde, JA Gaspar, E Rempel, NV Balmer, K Meganathan, ... Archives of toxicology 87, 123-143, 2013 | 249 | 2013 |
| Chemoprotective mechanism of the natural compounds, epigallocatechin-3-O-gallate, quercetin and curcumin against cancer and cardiovascular diseases S Jagtap, K Meganathan, V Wagh, J Winkler, J Hescheler, A Sachinidis Current medicinal chemistry 16 (12), 1451-1462, 2009 | 222 | 2009 |
| Transcriptomic landscape and functional characterization of induced pluripotent stem cell–derived cerebral organoids in schizophrenia A Kathuria, K Lopez-Lengowski, SS Jagtap, D McPhie, RH Perlis, ... JAMA psychiatry 77 (7), 745-754, 2020 | 119 | 2020 |
| Epigenetic changes and disturbed neural development in a human embryonic stem cell-based model relating to the fetal valproate syndrome NV Balmer, MK Weng, B Zimmer, VN Ivanova, SM Chambers, ... Human molecular genetics 21 (18), 4104-4114, 2012 | 116 | 2012 |
| Transcriptional and metabolic adaptation of human neurons to the mitochondrial toxicant MPP+ AK Krug, S Gutbier, L Zhao, D Pöltl, C Kullmann, V Ivanova, S Förster, ... Cell death & disease 5 (5), e1222-e1222, 2014 | 112 | 2014 |
| Identification of thalidomide-specific transcriptomics and proteomics signatures during differentiation of human embryonic stem cells K Meganathan, S Jagtap, V Wagh, J Winkler, JA Gaspar, D Hildebrand, ... Public Library of Science 7 (8), e44228, 2012 | 100 | 2012 |
| Development of a neural teratogenicity test based on human embryonic stem cells: response to retinoic acid exposure S Colleoni, C Galli, JA Gaspar, K Meganathan, S Jagtap, J Hescheler, ... Toxicological sciences 124 (2), 370-377, 2011 | 70 | 2011 |
| Definition of transcriptome-based indices for quantitative characterization of chemically disturbed stem cell development: introduction of the STOP-Tox ukn and STOP-Tox ukk tests V Shinde, L Hoelting, SP Srinivasan, J Meisig, K Meganathan, S Jagtap, ... Archives of toxicology 91, 839-864, 2017 | 61 | 2017 |
| Human pluripotent stem cell based developmental toxicity assays for chemical safety screening and systems biology data generation V Shinde, S Klima, PS Sureshkumar, K Meganathan, S Jagtap, E Rempel, ... JoVE (Journal of Visualized Experiments), e52333, 2015 | 57 | 2015 |
| Effects of cryopreservation on the transcriptome of human embryonic stem cells after thawing and culturing V Wagh, K Meganathan, S Jagtap, JA Gaspar, J Winkler, D Spitkovsky, ... Stem Cell Reviews and Reports 7, 506-517, 2011 | 53 | 2011 |
| Cytosine arabinoside induces ectoderm and inhibits mesoderm expression in human embryonic stem cells during multilineage differentiation S Jagtap, K Meganathan, J Gaspar, V Wagh, J Winkler, J Hescheler, ... British journal of pharmacology 162 (8), 1743-1756, 2011 | 50 | 2011 |
| Neuronal developmental gene and miRNA signatures induced by histone deacetylase inhibitors in human embryonic stem cells K Meganathan, S Jagtap, SP Srinivasan, V Wagh, J Hescheler, ... Cell death & disease 6 (5), e1756-e1756, 2015 | 47 | 2015 |
| All-trans retinoic acid and basic fibroblast growth factor synergistically direct pluripotent human embryonic stem cells to extraembryonic lineages S Jagtap, K Meganathan, V Wagh, K Natarajan, J Hescheler, A Sachinidis Stem Cell Research 10 (2), 228-240, 2013 | 24 | 2013 |
| Fam40b is required for lineage commitment of murine embryonic stem cells V Wagh, MX Doss, D Sabour, R Niemann, K Meganathan, S Jagtap, ... Cell Death & Disease 5 (7), e1320-e1320, 2014 | 21 | 2014 |
| Aberrant mitochondrial function in patient-derived neural cells from CDKL5 deficiency disorder and Rett syndrome S Jagtap, JM Thanos, T Fu, J Wang, J Lalonde, TO Dial, A Feiglin, J Chen, ... Human molecular genetics 28 (21), 3625-3636, 2019 | 20 | 2019 |
| Characterisation of a neural teratogenicity assay based on human ESCs differentiation following exposure to valproic acid S Colleoni, C Galli, J A Gaspar, K Meganathan, S Jagtap, J Hescheler, ... Current medicinal chemistry 19 (35), 6065-6071, 2012 | 19 | 2012 |
| Differences in the early development of human and mouse embryonic stem cells R Gabdoulline, W Kaisers, A Gaspar, K Meganathan, MX Doss, S Jagtap, ... PLoS One 10 (10), e0140803, 2015 | 17 | 2015 |
| A comparative transcriptomic study on the effects of valproic acid on two different hESCs lines in a neural teratogenicity test system S Colleoni, C Galli, JA Gaspar, K Meganathan, S Jagtap, J Hescheler, ... Toxicology Letters 231 (1), 38-44, 2014 | 17 | 2014 |
| Current status of human pluripotent stem cell based in vitro toxicity tests. M Klaric, J Winkler, K Vojnits, K Meganathan, S Jagtap, R Ensenat-Waser, ... Frontiers in Bioscience (Scholar Edition) 5 (1), 118-133, 2013 | 11 | 2013 |
| A tanscriptomics study to elucidate the toxicological mechanism of methylmercury chloride in a human stem cell based in vitro test K Vojnits, R Ensenat-Waser, J A Gaspar, K Meganathan, S Jagtap, ... Current medicinal chemistry 19 (36), 6224-6232, 2012 | 11 | 2012 |
Agapios SachinidisProfessor of PhysiologyVerified email at uni-koeln.de
