Bart Ghesquiere
Bart Ghesquiere
Head of Metabolomics Expertise Center, KULeuven-VIB
Geverifieerd e-mailadres voor kuleuven.vib.be
Geciteerd door
Geciteerd door
Role of PFKFB3-driven glycolysis in vessel sprouting
K De Bock, M Georgiadou, S Schoors, A Kuchnio, BW Wong, ...
Cell 154 (3), 651-663, 2013
A roadmap for interpreting 13C metabolite labeling patterns from cells
JM Buescher, MR Antoniewicz, LG Boros, SC Burgess, H Brunengraber, ...
Current opinion in biotechnology 34, 189-201, 2015
Tumour hypoxia causes DNA hypermethylation by reducing TET activity
B Thienpont, J Steinbacher, H Zhao, F D’Anna, A Kuchnio, A Ploumakis, ...
Nature 537 (7618), 63-68, 2016
Fatty acid carbon is essential for dNTP synthesis in endothelial cells
S Schoors, U Bruning, R Missiaen, K Queiroz, G Borgers, I Elia, A Zecchin, ...
Nature 520 (7546), 192-197, 2015
Partial and transient reduction of glycolysis by PFKFB3 blockade reduces pathological angiogenesis
S Schoors, K De Bock, AR Cantelmo, M Georgiadou, B Ghesquière, ...
Cell metabolism 19 (1), 37-48, 2014
Metabolism of stromal and immune cells in health and disease
B Ghesquière, BW Wong, A Kuchnio, P Carmeliet
Nature 511 (7508), 167-176, 2014
Inhibition of the glycolytic activator PFKFB3 in endothelium induces tumor vessel normalization, impairs metastasis, and improves chemotherapy
AR Cantelmo, LC Conradi, A Brajic, J Goveia, J Kalucka, A Pircher, ...
Cancer cell 30 (6), 968-985, 2016
Consensus guidelines for the use and interpretation of angiogenesis assays
P Nowak-Sliwinska, K Alitalo, E Allen, A Anisimov, AC Aplin, R Auerbach, ...
Angiogenesis 21 (3), 425-532, 2018
Tumor vessel normalization by chloroquine independent of autophagy
H Maes, A Kuchnio, A Peric, S Moens, K Nys, K De Bock, A Quaegebeur, ...
Cancer cell 26 (2), 190-206, 2014
The miR-17-92 microRNA cluster regulates multiple components of the TGF-β pathway in neuroblastoma
P Mestdagh, AK Boström, F Impens, E Fredlund, G Van Peer, ...
Molecular cell 40 (5), 762-773, 2010
Macrophage metabolism controls tumor blood vessel morphogenesis and metastasis
M Wenes, M Shang, M Di Matteo, J Goveia, R Martín-Pérez, J Serneels, ...
Cell metabolism 24 (5), 701-715, 2016
Histamine receptor H1–mediated sensitization of TRPV1 mediates visceral hypersensitivity and symptoms in patients with irritable bowel syndrome
MM Wouters, D Balemans, S Van Wanrooy, J Dooley, V Cibert-Goton, ...
Gastroenterology 150 (4), 875-887. e9, 2016
The role of fatty acid β-oxidation in lymphangiogenesis
BW Wong, X Wang, A Zecchin, B Thienpont, I Cornelissen, J Kalucka, ...
Nature 542 (7639), 49-54, 2017
Pharmacologic or genetic targeting of glutamine synthetase skews macrophages toward an M1-like phenotype and inhibits tumor metastasis
EM Palmieri, A Menga, R Martín-Pérez, A Quinto, C Riera-Domingo, ...
Cell reports 20 (7), 1654-1666, 2017
A fatty acid oxidation-dependent metabolic shift regulates adult neural stem cell activity
M Knobloch, GA Pilz, B Ghesquière, WJ Kovacs, T Wegleiter, DL Moore, ...
Cell reports 20 (9), 2144-2155, 2017
Role of glutamine and interlinked asparagine metabolism in vessel formation
H Huang, S Vandekeere, J Kalucka, L Bierhansl, A Zecchin, U Brüning, ...
The EMBO journal 36 (16), 2334-2352, 2017
Stable isotopic labeling in proteomics
K Gevaert, F Impens, B Ghesquière, P Van Damme, A Lambrechts, ...
Proteomics 8 (23‐24), 4873-4885, 2008
Metabolites released from apoptotic cells act as tissue messengers
CB Medina, P Mehrotra, S Arandjelovic, JSA Perry, Y Guo, S Morioka, ...
Nature 580 (7801), 130-135, 2020
Redox proteomics of protein-bound methionine oxidation
B Ghesquiere, V Jonckheere, N Colaert, J Van Durme, E Timmerman, ...
Molecular & Cellular Proteomics 10 (5), 2011
Codon-specific translation reprogramming promotes resistance to targeted therapy
F Rapino, S Delaunay, F Rambow, Z Zhou, L Tharun, P De Tullio, O Sin, ...
Nature 558 (7711), 605-609, 2018
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