| Enhanced neurofibrillary degeneration in transgenic mice expressing mutant tau and APP J Lewis, DW Dickson, WL Lin, L Chisholm, A Corral, G Jones, SH Yen, ... Science 293 (5534), 1487-1491, 2001 | 2095 | 2001 |
| Propagation of tau pathology in a model of early Alzheimer's disease A De Calignon, M Polydoro, M Suárez-Calvet, C William, DH Adamowicz, ... Neuron 73 (4), 685-697, 2012 | 1553 | 2012 |
| Imaging of tau pathology in a tauopathy mouse model and in Alzheimer patients compared to normal controls M Maruyama, H Shimada, T Suhara, H Shinotoh, B Ji, J Maeda, ... Neuron 79 (6), 1094-1108, 2013 | 848 | 2013 |
| Granular tau oligomers as intermediates of tau filaments S Maeda, N Sahara, Y Saito, M Murayama, Y Yoshiike, H Kim, T Miyasaka, ... Biochemistry 46 (12), 3856-3861, 2007 | 364 | 2007 |
| Increased levels of granular tau oligomers: an early sign of brain aging and Alzheimer's disease S Maeda, N Sahara, Y Saito, S Murayama, A Ikai, A Takashima Neuroscience research 54 (3), 197-201, 2006 | 349 | 2006 |
| Argyrophilic grain disease is a sporadic 4-repeat tauopathy T Togo, N Sahara, SH Yen, N Cookson, T Ishizawa, M Hutton, R De Silva, ... Journal of Neuropathology & Experimental Neurology 61 (6), 547-556, 2002 | 303 | 2002 |
| In vivo evidence of CHIP up‐regulation attenuating tau aggregation N Sahara, M Murayama, T Mizoroki, M Urushitani, Y Imai, R Takahashi, ... Journal of neurochemistry 94 (5), 1254-1263, 2005 | 246 | 2005 |
| APP717 missense mutation affects the ratio of amyloid beta protein species (A beta 1-42/43 and a beta 1-40) in familial Alzheimer's disease brain A Tamaoka, A Odaka, Y Ishibashi, M Usami, N Sahara, N Suzuki, ... Journal of Biological Chemistry 269 (52), 32721-32724, 1994 | 238 | 1994 |
| Distinct binding of PET ligands PBB3 and AV-1451 to tau fibril strains in neurodegenerative tauopathies M Ono, N Sahara, K Kumata, B Ji, R Ni, S Koga, DW Dickson, ... Brain 140 (3), 764-780, 2017 | 225 | 2017 |
| Assembly of two distinct dimers and higher‐order oligomers from full‐length tau N Sahara, S Maeda, M Murayama, T Suzuki, N Dohmae, SH Yen, ... European Journal of Neuroscience 25 (10), 3020-3029, 2007 | 215 | 2007 |
| High-contrast in vivo imaging of tau pathologies in Alzheimer’s and non-Alzheimer’s disease tauopathies K Tagai, M Ono, M Kubota, S Kitamura, K Takahata, C Seki, Y Takado, ... Neuron 109 (1), 42-58. e8, 2021 | 208 | 2021 |
| Microglial gene signature reveals loss of homeostatic microglia associated with neurodegeneration of Alzheimer’s disease A Sobue, O Komine, Y Hara, F Endo, H Mizoguchi, S Watanabe, ... Acta neuropathologica communications 9, 1-17, 2021 | 168 | 2021 |
| Hyperphosphorylated tau in parahippocampal cortex impairs place learning in aged mice expressing wild‐type human tau T Kimura, S Yamashita, T Fukuda, JM Park, M Murayama, T Mizoroki, ... The EMBO journal 26 (24), 5143-5152, 2007 | 168 | 2007 |
| GSK-3β is required for memory reconsolidation in adult brain T Kimura, S Yamashita, S Nakao, JM Park, M Murayama, T Mizoroki, ... PloS one 3 (10), e3540, 2008 | 161 | 2008 |
| Promotion of CHIP-mediated p53 degradation protects the heart from ischemic injury AT Naito, S Okada, T Minamino, K Iwanaga, ML Liu, T Sumida, S Nomura, ... Circulation research 106 (11), 1692-1702, 2010 | 156 | 2010 |
| Assembly of tau in transgenic animals expressing P301L tau: alteration of phosphorylation and solubility N Sahara, J Lewis, M DeTure, E McGowan, DW Dickson, M Hutton, ... Journal of neurochemistry 83 (6), 1498-1508, 2002 | 150 | 2002 |
| Biochemical evidence for the long-tail form (Aβ1-42/43) of amyloid β protein as a seed molecule in cerebral deposits of alzheimer′ s disease A Tamaoka, T Kondo, A Odaka, N Sahara, N Sawamura, K Ozawa, ... Biochemical and biophysical research communications 205 (1), 834-842, 1994 | 149 | 1994 |
| Cryo-EM structures of tau filaments from Alzheimer’s disease with PET ligand APN-1607 Y Shi, AG Murzin, B Falcon, A Epstein, J Machin, P Tempest, KL Newell, ... Acta neuropathologica 141, 697-708, 2021 | 139 | 2021 |
| Characteristics of TBS-extractable hyperphosphorylated tau species: aggregation intermediates in rTg4510 mouse brain N Sahara, M DeTure, Y Ren, AS Ebrahim, D Kang, J Knight, C Volbracht, ... Journal of Alzheimer’s disease 33 (1), 249-263, 2012 | 122 | 2012 |
| PET quantification of tau pathology in human brain with 11C-PBB3 Y Kimura, M Ichise, H Ito, H Shimada, Y Ikoma, C Seki, H Takano, ... Journal of Nuclear Medicine 56 (9), 1359-1365, 2015 | 117 | 2015 |
Dennis W. DicksonMayo ClinicVerified email at mayo.edu
