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Jarrett R. Remsberg
Jarrett R. Remsberg
Adresse e-mail validée de scripps.edu
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Année
Discrete functions of nuclear receptor Rev-erbα couple metabolism to the clock
Y Zhang, B Fang, MJ Emmett, M Damle, Z Sun, D Feng, SM Armour, ...
Science 348 (6242), 1488-1492, 2015
3042015
Expedited mapping of the ligandable proteome using fully functionalized enantiomeric probe pairs
Y Wang, MM Dix, G Bianco, JR Remsberg, HY Lee, M Kalocsay, SP Gygi, ...
Nature chemistry 11 (12), 1113-1123, 2019
1022019
An HDAC3-PROX1 corepressor module acts on HNF4α to control hepatic triglycerides
SM Armour, JR Remsberg, M Damle, S Sidoli, WY Ho, Z Li, BA Garcia, ...
Nature communications 8 (1), 1-11, 2017
612017
Circadian lipid synthesis in brown fat maintains murine body temperature during chronic cold
M Adlanmerini, BJ Carpenter, JR Remsberg, Y Aubert, LC Peed, ...
Proceedings of the National Academy of Sciences 116 (37), 18691-18699, 2019
562019
Deletion of histone deacetylase 3 in adult beta cells improves glucose tolerance via increased insulin secretion
JR Remsberg, BN Ediger, WY Ho, M Damle, Z Li, C Teng, C Lanzillotta, ...
Molecular metabolism 6 (1), 30-37, 2017
542017
Structural analogues of smoothened intracellular loops as potent inhibitors of Hedgehog pathway and cancer cell growth
JR Remsberg, H Lou, SG Tarasov, M Dean, NI Tarasova
Journal of medicinal chemistry 50 (18), 4534-4538, 2007
542007
ABHD17 regulation of plasma membrane palmitoylation and N-Ras-dependent cancer growth
JR Remsberg, RM Suciu, NA Zambetti, TW Hanigan, AJ Firestone, ...
Nature chemical biology 17 (8), 856-864, 2021
502021
Proteomic discovery of chemical probes that perturb protein complexes in human cells
MR Lazear, JR Remsberg, MG Jaeger, K Rothamel, H Her, KE DeMeester, ...
Molecular Cell 83 (10), 1725-1742. e12, 2023
342023
A coregulator shift, rather than the canonical switch, underlies thyroid hormone action in the liver
Y Shabtai, NK Nagaraj, K Batmanov, YW Cho, Y Guan, C Jiang, ...
Genes & Development 35 (5-6), 367-378, 2021
252021
Peptide Structure Stabilization by Membrane Anchoring and its General Applicability to the Development of Potent Cell‐Permeable Inhibitors
L Johannessen, J Remsberg, V Gaponenko, KM Adams, JJ Barchi Jr, ...
ChemBioChem 12 (6), 914-921, 2011
252011
Remodeling oncogenic transcriptomes by small molecules targeting NONO
SG Kathman, SJ Koo, GL Lindsey, HL Her, SM Blue, H Li, S Jaensch, ...
Nature chemical biology 19 (7), 825-836, 2023
202023
Genetic disruption of N-RasG12D palmitoylation perturbs hematopoiesis and prevents myeloid transformation in mice
NA Zambetti, AJ Firestone, JR Remsberg, BJ Huang, JC Wong, AM Long, ...
Blood, The Journal of the American Society of Hematology 135 (20), 1772-1782, 2020
152020
Assigning functionality to cysteines by base editing of cancer dependency genes
H Li, T Ma, JR Remsberg, SJ Won, KE DeMeester, E Njomen, ...
Nature chemical biology 19 (11), 1320-1330, 2023
122023
Chemical Proteomic Discovery of Isotype‐Selective Covalent Inhibitors of the RNA Methyltransferase NSUN2
Y Tao, JG Felber, Z Zou, E Njomen, JR Remsberg, D Ogasawara, C Ye, ...
Angewandte Chemie International Edition 62 (51), e202311924, 2023
32023
ABHD17 enzymes regulate dynamic plasma membrane palmitoylation and N-Ras-dependent cancer growth
JR Remsberg, RM Suciu, NA Zambetti, TW Hanigan, AJ Firestone, ...
bioRxiv, 2020.05. 21.108316, 2020
22020
Proteomic Ligandability Maps of Spirocycle Acrylamide Stereoprobes Identify Covalent ERCC3 Degraders
Z Liu, JR Remsberg, H Li, E Njomen, KE DeMeester, Y Tao, G Xia, ...
Journal of the American Chemical Society, 2024
12024
Redirecting the pioneering function of FOXA1 with covalent small molecules
SJ Won, Y Zhang, CJ Reinhardt, NS MacRae, KE DeMeester, E Njomen, ...
bioRxiv, 2024.03. 21.586158, 2024
2024
Thyroid Hormone Action in Liver: A Coregulator Shift Rather Than the Canonical Switch
Y Shabtai, NK Nagaraj, K Batmanov, YW Cho, Y Guan, C Jiang, ...
Journal of the Endocrine Society 5 (Supplement_1), A980-A980, 2021
2021
In vivo evidence validating the palmitoylation/depalmitoylation cycle as a therapeutic target in NRAS mutant hematologic cancers.
NA Zambetti, AJ Firestone, JC Wong, AM Long, A Inguva, JR Remsberg, ...
MOLECULAR CANCER RESEARCH 18 (5), 44-45, 2020
2020
Abstract A25: In vivo evidence validating the palmitoylation/depalmitoylation cycle as a therapeutic target in NRAS mutant hematologic cancers
NA Zambetti, AJ Firestone, JC Wong, AM Long, A Inguva, JR Remsberg, ...
Molecular Cancer Research 18 (5_Supplement), A25-A25, 2020
2020
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