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Nicole Robbins
Nicole Robbins
Senior Research Associate, University of Toronto
Geverifieerd e-mailadres voor mcmaster.ca
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Regulatory circuitry governing fungal development, drug resistance, and disease
RS Shapiro, N Robbins, LE Cowen
Microbiology and molecular biology reviews 75 (2), 213-267, 2011
7002011
Antifungal drug resistance: evolution, mechanisms and impact
NM Revie, KR Iyer, N Robbins, LE Cowen
Current opinion in microbiology 45, 70-76, 2018
4592018
Antifungal Drug Resistance: Molecular Mechanisms in Candida albicans and Beyond
Y Lee, E Puumala, N Robbins, LE Cowen
Chemical reviews 121 (6), 3390-3411, 2020
4312020
Hsp90 Governs Echinocandin Resistance in the Pathogenic Yeast Candida albicans via Calcineurin
SD Singh, N Robbins, AK Zaas, WA Schell, JR Perfect, LE Cowen
PLoS pathogens 5 (7), e1000532, 2009
3922009
Molecular evolution of antifungal drug resistance
N Robbins, T Caplan, LE Cowen
Annual review of microbiology 71, 753-775, 2017
3752017
Hsp90 governs dispersion and drug resistance of fungal biofilms
N Robbins, P Uppuluri, J Nett, R Rajendran, G Ramage, JL Lopez-Ribot, ...
PLoS pathogens 7 (9), e1002257, 2011
3242011
Antifungal drugs: the current armamentarium and development of new agents
N Robbins, GD Wright, LE Cowen
Microbiology spectrum 4 (5), 10.1128/microbiolspec. funk-0002-2016, 2016
2212016
Combinatorial strategies for combating invasive fungal infections
M Spitzer, N Robbins, GD Wright
Virulence 8 (2), 169-185, 2017
1892017
Treatment strategies for cryptococcal infection: challenges, advances and future outlook
KR Iyer, NM Revie, C Fu, N Robbins, LE Cowen
Nature Reviews Microbiology 19 (7), 454-466, 2021
1802021
Genetic Analysis of Candida auris Implicates Hsp90 in Morphogenesis and Azole Tolerance and Cdr1 in Azole Resistance
SH Kim, KR Iyer, L Pardeshi, JF Muñoz, N Robbins, CA Cuomo, KH Wong, ...
MBio 10 (1), 10.1128/mbio. 02529-18, 2019
1222019
Lysine deacetylases Hda1 and Rpd3 regulate Hsp90 function thereby governing fungal drug resistance
N Robbins, MD Leach, LE Cowen
Cell reports 2 (4), 878-888, 2012
1202012
Structural basis for species-selective targeting of Hsp90 in a pathogenic fungus
L Whitesell, N Robbins, DS Huang, CA McLellan, T Shekhar-Guturja, ...
Nature communications 10 (1), 402, 2019
982019
The Hsp90 chaperone network modulates Candida virulence traits
TR O’Meara, N Robbins, LE Cowen
Trends in microbiology 25 (10), 809-819, 2017
832017
An antifungal combination matrix identifies a rich pool of adjuvant molecules that enhance drug activity against diverse fungal pathogens
N Robbins, M Spitzer, T Yu, RP Cerone, AK Averette, YS Bahn, J Heitman, ...
Cell reports 13 (7), 1481-1492, 2015
772015
A small molecule produced by Lactobacillus species blocks Candida albicans filamentation by inhibiting a DYRK1-family kinase
J MacAlpine, M Daniel-Ivad, Z Liu, J Yano, NM Revie, RT Todd, ...
Nature communications 12 (1), 6151, 2021
652021
The Candida albicans transcription factor Cas5 couples stress responses, drug resistance and cell cycle regulation
JL Xie, L Qin, Z Miao, BT Grys, JDLC Diaz, K Ting, JR Krieger, J Tong, ...
Nature communications 8 (1), 499, 2017
602017
Design and synthesis of fungal-selective resorcylate aminopyrazole Hsp90 inhibitors
DS Huang, EV LeBlanc, T Shekhar-Guturja, N Robbins, DJ Krysan, ...
Journal of medicinal chemistry 63 (5), 2139-2180, 2019
582019
Functional genomic screening reveals core modulators of echinocandin stress responses in Candida albicans
T Caplan, EJ Polvi, JL Xie, S Buckhalter, MD Leach, N Robbins, ...
Cell reports 23 (8), 2292-2298, 2018
582018
Leveraging machine learning essentiality predictions and chemogenomic interactions to identify antifungal targets
C Fu, X Zhang, AO Veri, KR Iyer, E Lash, A Xue, H Yan, NM Revie, ...
Nature communications 12 (1), 6497, 2021
492021
Metal chelation as a powerful strategy to probe cellular circuitry governing fungal drug resistance and morphogenesis
EJ Polvi, AF Averette, SC Lee, T Kim, YS Bahn, AO Veri, N Robbins, ...
PLoS genetics 12 (10), e1006350, 2016
482016
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Artikelen 1–20