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Nathan Heath Patterson
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The human body at cellular resolution: the NIH Human Biomolecular Atlas Program
Caltech-UW TMC Cai Long lcai@ caltech. edu 21 b Shendure Jay 9 Trapnell Cole ...
Nature 574 (7777), 187-192, 2019
3692019
Accumulation of long-chain fatty acids in the tumor microenvironment drives dysfunction in intrapancreatic CD8+ T cells
T Manzo, BM Prentice, KG Anderson, A Raman, A Schalck, GS Codreanu, ...
Journal of Experimental Medicine 217 (8), 2020
1652020
Advanced registration and analysis of MALDI imaging mass spectrometry measurements through autofluorescence microscopy
NH Patterson, M Tuck, R Van de Plas, RM Caprioli
Analytical chemistry 90 (21), 12395-12403, 2018
912018
Histology-driven data mining of lipid signatures from multiple imaging mass spectrometry analyses: application to human colorectal cancer liver metastasis biopsies
A Thomas, NH Patterson, MM Marcinkiewicz, A Lazaris, P Metrakos, ...
Analytical chemistry 85 (5), 2860-2866, 2013
832013
Uncovering matrix effects on lipid analyses in MALDI imaging mass spectrometry experiments
WJ Perry, NH Patterson, BM Prentice, EK Neumann, RM Caprioli, ...
Journal of mass spectrometry 55 (4), e4491, 2020
662020
Monitoring time‐dependent degradation of phospholipids in sectioned tissues by MALDI imaging mass spectrometry
NH Patterson, A Thomas, P Chaurand
Journal of Mass spectrometry 49 (7), 622-627, 2014
622014
MicroLESA: integrating autofluorescence microscopy, in situ micro-digestions, and liquid extraction surface analysis for high spatial resolution targeted proteomic studies
DJ Ryan, NH Patterson, NE Putnam, AD Wilde, A Weiss, WJ Perry, ...
Analytical chemistry 91 (12), 7578-7585, 2019
582019
Next generation histology-directed imaging mass spectrometry driven by autofluorescence microscopy
NH Patterson, M Tuck, A Lewis, A Kaushansky, JL Norris, R Van de Plas, ...
Analytical chemistry 90 (21), 12404-12413, 2018
562018
Combining salt doping and matrix sublimation for high spatial resolution MALDI imaging mass spectrometry of neutral lipids
M Dufresne, NH Patterson, JL Norris, RM Caprioli
Analytical chemistry 91 (20), 12928-12934, 2019
552019
Multimodal imaging based on vibrational spectroscopies and mass spectrometry imaging applied to biological tissue: a multiscale and multiomics review
M Tuck, L Blanc, R Touti, NH Patterson, S Van Nuffel, S Villette, ...
Analytical chemistry 93 (1), 445-477, 2020
542020
Multimodal detection of GM2 and GM3 lipid species in the brain of mucopolysaccharidosis type II mouse by serial imaging mass spectrometry and immunohistochemistry
M Dufresne, D Guneysu, NH Patterson, MM Marcinkiewicz, A Regina, ...
Analytical and bioanalytical chemistry 409, 1425-1433, 2017
522017
Three‐dimensional imaging MS of lipids in atherosclerotic plaques: Open‐source methods for reconstruction and analysis
NH Patterson, RJ Doonan, SS Daskalopoulou, M Dufresne, S Lenglet, ...
Proteomics 16 (11-12), 1642-1651, 2016
522016
Assessment of pathological response to therapy using lipid mass spectrometry imaging
NH Patterson, B Alabdulkarim, A Lazaris, A Thomas, MM Marcinkiewicz, ...
Scientific reports 6 (1), 36814, 2016
472016
Orthogonal organic and aqueous‐based washes of tissue sections to enhance protein sensitivity by MALDI imaging mass spectrometry
A Thomas, NH Patterson, J Laveaux Charbonneau, P Chaurand
Journal of Mass Spectrometry 48 (1), 42-48, 2013
472013
A recommended and verified procedure for in situ tryptic digestion of formalin‐fixed paraffin‐embedded tissues for analysis by matrix‐assisted laser desorption …
AM Judd, DB Gutierrez, JL Moore, NH Patterson, J Yang, CE Romer, ...
Journal of mass spectrometry 54 (8), 716-727, 2019
462019
Mapping the triglyceride distribution in NAFLD human liver by MALDI imaging mass spectrometry reveals molecular differences in micro and macro steatosis
H Alamri, NH Patterson, E Yang, P Zoroquiain, A Lazaris, P Chaurand, ...
Analytical and bioanalytical chemistry 411, 885-894, 2019
382019
Lipid landscape of the human retina and supporting tissues revealed by high-resolution imaging mass spectrometry
DMG Anderson, JD Messinger, NH Patterson, ES Rivera, A Kotnala, ...
Journal of the American Society for Mass Spectrometry 31 (12), 2426-2436, 2020
372020
Discovering new lipidomic features using cell type specific fluorophore expression to provide spatial and biological specificity in a multimodal workflow with MALDI imaging …
MA Jones, SH Cho, NH Patterson, R Van de Plas, JM Spraggins, ...
Analytical chemistry 92 (10), 7079-7086, 2020
342020
Single-cell mass spectrometry reveals changes in lipid and metabolite expression in RAW 264.7 cells upon lipopolysaccharide stimulation
B Yang, NH Patterson, T Tsui, RM Caprioli, JL Norris
Journal of The American Society for Mass Spectrometry 29 (5), 1012-1020, 2018
332018
Co-registration and analysis of multiple imaging mass spectrometry datasets targeting different analytes
NH Patterson, E Yang, EA Kranjec, P Chaurand
Bioinformatics 35 (7), 1261-1262, 2019
312019
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