| Increasing the homogeneity, stability and activity of human serum albumin and interferon-α2b fusion protein by linker engineering HL Zhao, XQ Yao, C Xue, Y Wang, XH Xiong, ZM Liu Protein expression and purification 61 (1), 73-77, 2008 | 197 | 2008 |
| Enhanced Secretion of Heterologous Proteins in Pichia pastoris Following Overexpression of Saccharomyces cerevisiae Chaperone Proteins W Zhang, H Zhao, C Xue, X Xiong, X Yao, X Li, H Chen, Z Liu Biotechnology progress 22 (4), 1090-1095, 2006 | 109 | 2006 |
| Circumventing the heterogeneity and instability of human serum albumin-interferon-α2b fusion protein by altering its orientation HL Zhao, C Xue, Y Wang, XY Li, XH Xiong, XQ Yao, ZM Liu Journal of biotechnology 131 (3), 245-252, 2007 | 63 | 2007 |
| Depletion of T cell epitopes in lysostaphin mitigates anti-drug antibody response and enhances antibacterial efficacy in vivo H Zhao, D Verma, W Li, Y Choi, C Ndong, SN Fiering, C Bailey-Kellogg, ... Chemistry & biology 22 (5), 629-639, 2015 | 56 | 2015 |
| Increasing the cell viability and heterologous protein expression of Pichia pastoris mutant deficient in PMR1 gene by culture condition optimization HL Zhao, C Xue, Y Wang, XQ Yao, ZM Liu Applied microbiology and biotechnology 81, 235-241, 2008 | 48 | 2008 |
| Structure-based redesign of lysostaphin yields potent antistaphylococcal enzymes that evade immune cell surveillance K Blazanovic, H Zhao, Y Choi, W Li, RS Salvat, DC Osipovitch, J Fields, ... Molecular therapy Methods & clinical development 2, 2015 | 43 | 2015 |
| Gene and protein sequence optimization for high-level production of fully active and aglycosylated lysostaphin in Pichia pastoris H Zhao, K Blazanovic, Y Choi, C Bailey-Kellogg, KE Griswold Applied and environmental microbiology 80 (9), 2746-2753, 2014 | 41 | 2014 |
| Elimination of the free sulfhydryl group in the human serum albumin (HSA) moiety of human interferon-α2b and HSA fusion protein increases its stability against mechanical and … HL Zhao, C Xue, Y Wang, B Sun, XQ Yao, ZM Liu European journal of pharmaceutics and biopharmaceutics 72 (2), 405-411, 2009 | 35 | 2009 |
| Degradation of HSA-AX15 (R13K) when expressed in Pichia pastoris can be reduced via the disruption of YPS1 gene in this yeast XQ Yao, HL Zhao, C Xue, W Zhang, XH Xiong, ZW Wang, XY Li, ZM Liu Journal of biotechnology 139 (2), 131-136, 2009 | 33 | 2009 |
| Balancing the pharmacokinetics and pharmacodynamics of interferon-α2b and human serum albumin fusion protein by proteolytic or reductive cleavage increases its in vivo … HL Zhao, C Xue, JL Du, M Ren, S Xia, ZM Liu Molecular Pharmaceutics 9 (3), 664-670, 2012 | 32 | 2012 |
| Globally deimmunized lysostaphin evades human immune surveillance and enables highly efficacious repeat dosing H Zhao, SA Brooks, S Eszterhas, S Heim, L Li, YQ Xiong, Y Fang, ... Science advances 6 (36), eabb9011, 2020 | 26 | 2020 |
| Sustained and cancer cell targeted cytosolic delivery of Onconase results in potent antitumor effects HL Zhao, C Xue, JL Du, M Ren, S Xia, YG Cheng, ZM Liu Journal of controlled release 159 (3), 346-352, 2012 | 22 | 2012 |
| Recombinant heat shock protein 65 carrying hepatitis B core antigen induces HBcAg-specific CTL response B Yang, H Zhao, C Xue, X Xiong, W Zhang, X Yao, Z Liu Vaccine 25 (22), 4478-4486, 2007 | 22 | 2007 |
| Secretory expression of glycosylated and aglycosylated mutein of onconase from Pichia pastoris using different secretion signals and their purification and … HL Zhao, Q He, C Xue, B Sun, XQ Yao, ZM Liu FEMS yeast research 9 (4), 591-599, 2009 | 20 | 2009 |
| Deimmunized Lysostaphin Synergizes with Small-Molecule Chemotherapies and Resensitizes Methicillin-Resistant Staphylococcus aureus to β-Lactam Antibiotics Y Fang, JR Kirsch, L Li, SA Brooks, S Heim, C Tan, S Eszterhas, ... Antimicrobial Agents and Chemotherapy 65 (3), 10.1128/aac. 01707-20, 2021 | 11 | 2021 |
| Secretory expression and characterization of a recombinant-deleted variant of human hepatocyte growth factor in Pichia pastoris ZM Liu, HL Zhao, C Xue, BB Deng, W Zhang, XH Xiong, BF Yang, XQ Yao World Journal of Gastroenterology 11 (45), 7097, 2005 | 9 | 2005 |
| Protein glycoengineering Z Hongliang, L Zhimin Zhongguo Sheng wu Gong Cheng za zhi= Journal of Chinese Biotechnology 23 (9 …, 2003 | 9 | 2003 |
| Disruption of Pichia pastoris PMR1 gene decreases its folding capacity on human serum albumin and interferon‐α2b fusion protein HL Zhao, C Xue, Y Wang, QF Duan, XH Xiong, XQ Yao, ZM Liu Yeast 25 (4), 279-286, 2008 | 6 | 2008 |
| GC rapid analysis of methanol and ethanol during high cell density culture of recombinant methylotrophic yeast BB Deng, HQ Feng, C Xue Chin. Ind. Microbiol 31, 26-29, 2001 | 6 | 2001 |
| Electrostatic-Mediated Affinity Tuning of Lysostaphin Accelerates Bacterial Lysis Kinetics and Enhances In Vivo Efficacy H Zhao, S Eszterhas, J Furlon, H Cheng, KE Griswold Antimicrobial Agents and Chemotherapy 65 (4), 10.1128/aac. 02199-20, 2021 | 4 | 2021 |
Karl E GriswoldTexas State University, University of Texas, Huntsman, Dartmouth, Thayer, Dartmouth EngineeringGeverifieerd e-mailadres voor dartmouth.edu
