Role of deficient type III interferon-λ production in asthma exacerbations M Contoli, SD Message, V Laza-Stanca, MR Edwards, PAB Wark, ... Nature medicine 12 (9), 1023-1026, 2006 | 1200 | 2006 |
IL-33–dependent type 2 inflammation during rhinovirus-induced asthma exacerbations in vivo DJ Jackson, H Makrinioti, BMJ Rana, BWH Shamji, MB Trujillo-Torralbo, ... American journal of respiratory and critical care medicine 190 (12), 1373-1382, 2014 | 657 | 2014 |
Targeting the NF-κB pathway in asthma and chronic obstructive pulmonary disease MR Edwards, NW Bartlett, D Clarke, M Birrell, M Belvisi, SL Johnston Pharmacology & therapeutics 121 (1), 1-13, 2009 | 483 | 2009 |
The poxvirus protein A52R targets Toll-like receptor signaling complexes to suppress host defense MT Harte, IR Haga, G Maloney, P Gray, PC Reading, NW Bartlett, ... The Journal of experimental medicine 197 (3), 343-351, 2003 | 473 | 2003 |
Vaccinia virus protein A46R targets multiple Toll-like–interleukin-1 receptor adaptors and contributes to virulence J Stack, IR Haga, M Schröder, NW Bartlett, G Maloney, PC Reading, ... The Journal of experimental medicine 201 (6), 1007-1018, 2005 | 453 | 2005 |
Mouse models of rhinovirus-induced disease and exacerbation of allergic airway inflammation NW Bartlett, RP Walton, MR Edwards, J Aniscenko, G Caramori, J Zhu, ... Nature medicine 14 (2), 199-204, 2008 | 426 | 2008 |
Rhinovirus-induced IL-25 in asthma exacerbation drives type 2 immunity and allergic pulmonary inflammation J Beale, A Jayaraman, DJ Jackson, JDR Macintyre, MR Edwards, ... Science translational medicine 6 (256), 256ra134-256ra134, 2014 | 382 | 2014 |
Co-ordinated role of TLR3, RIG-I and MDA5 in the innate response to rhinovirus in bronchial epithelium L Slater, NW Bartlett, JJ Haas, J Zhu, SD Message, RP Walton, A Sykes, ... PLoS pathogens 6 (11), e1001178, 2010 | 337 | 2010 |
Host DNA released by NETosis promotes rhinovirus-induced type-2 allergic asthma exacerbation M Toussaint, DJ Jackson, D Swieboda, A Guedán, TD Tsourouktsoglou, ... Nature medicine 23 (6), 681-691, 2017 | 329 | 2017 |
The microbiology of asthma MR Edwards, NW Bartlett, T Hussell, P Openshaw, SL Johnston Nature Reviews Microbiology 10 (7), 459-471, 2012 | 261 | 2012 |
Functional and structural studies of the vaccinia virus virulence factor N1 reveal a Bcl-2-like anti-apoptotic protein S Cooray, MW Bahar, NGA Abrescia, CE McVey, NW Bartlett, RAJ Chen, ... Journal of general virology 88 (6), 1656-1666, 2007 | 201 | 2007 |
Corticosteroid suppression of antiviral immunity increases bacterial loads and mucus production in COPD exacerbations A Singanayagam, N Glanville, JL Girkin, YM Ching, A Marcellini, ... Nature communications 9 (1), 2229, 2018 | 192 | 2018 |
Murine interferon lambdas (type III interferons) exhibit potent antiviral activity in vivo in a poxvirus infection model NW Bartlett, K Buttigieg, SV Kotenko, GL Smith Journal of General Virology 86 (6), 1589-1596, 2005 | 173 | 2005 |
The E3 ubiquitin ligase midline 1 promotes allergen and rhinovirus-induced asthma by inhibiting protein phosphatase 2A activity A Collison, L Hatchwell, N Verrills, PAB Wark, AP De Siqueira, M Tooze, ... Nature medicine 19 (2), 232-237, 2013 | 160 | 2013 |
Inhaled corticosteroids downregulate the SARS-CoV-2 receptor ACE2 in COPD through suppression of type I interferon LJ Finney, N Glanville, H Farne, J Aniscenko, P Fenwick, SV Kemp, ... Journal of Allergy and Clinical Immunology 147 (2), 510-519. e5, 2021 | 158 | 2021 |
Evidence for the involvement of type I interferon in pulmonary arterial hypertension PM George, E Oliver, P Dorfmuller, OD Dubois, DM Reed, NS Kirkby, ... Circulation research 114 (4), 677-688, 2014 | 149 | 2014 |
The vaccinia virus N1L protein is an intracellular homodimer that promotes virulence N Bartlett, JA Symons, DC Tscharke, GL Smith Journal of General Virology 83 (8), 1965-1976, 2002 | 148 | 2002 |
A comprehensive evaluation of nasal and bronchial cytokines and chemokines following experimental rhinovirus infection in allergic asthma: increased interferons (IFN-γ and IFN … TT Hansel, T Tunstall, MB Trujillo-Torralbo, B Shamji, A Del-Rosario, ... EBioMedicine 19, 128-138, 2017 | 141 | 2017 |
Toll-like receptor 7 governs interferon and inflammatory responses to rhinovirus and is suppressed by IL-5-induced lung eosinophilia L Hatchwell, A Collison, J Girkin, K Parsons, J Li, J Zhang, S Phipps, ... Thorax 70 (9), 854-861, 2015 | 115 | 2015 |
Rhinovirus induces MUC5AC in a human infection model and in vitro via NF-κB and EGFR pathways CA Hewson, JJ Haas, NW Bartlett, V Laza-Stanca, T Kebadze, ... European Respiratory Journal 36 (6), 1425-1435, 2010 | 115 | 2010 |