A ChIP-seq defined genome-wide map of vitamin D receptor binding: associations with disease and evolution SV Ramagopalan, A Heger, AJ Berlanga, NJ Maugeri, MR Lincoln, ... Genome research 20 (10), 1352-1360, 2010 | 891 | 2010 |
An updated meta-analysis of risk of multiple sclerosis following infectious mononucleosis AE Handel, AJ Williamson, G Disanto, L Handunnetthi, G Giovannoni, ... PloS one 5 (9), e12496, 2010 | 312 | 2010 |
Environmental factors and their timing in adult-onset multiple sclerosis AE Handel, G Giovannoni, GC Ebers, SV Ramagopalan Nature Reviews Neurology 6 (3), 156-166, 2010 | 289 | 2010 |
Smoking and multiple sclerosis: an updated meta-analysis AE Handel, AJ Williamson, G Disanto, R Dobson, G Giovannoni, ... PloS one 6 (1), e16149, 2011 | 284 | 2011 |
Epigenetics: molecular mechanisms and implications for disease AE Handel, GC Ebers, SV Ramagopalan Trends in molecular medicine 16 (1), 7-16, 2010 | 259 | 2010 |
Risk of venous thromboembolism in people admitted to hospital with selected immune-mediated diseases: record-linkage study SV Ramagopalan, CJ Wotton, AE Handel, D Yeates, MJ Goldacre BMC medicine 9 (1), 1, 2011 | 231 | 2011 |
Rare variants in the CYP27B1 gene are associated with multiple sclerosis SV Ramagopalan, DA Dyment, MZ Cader, KM Morrison, G Disanto, ... Annals of neurology 70 (6), 881-886, 2011 | 228 | 2011 |
Relationship of UV exposure to prevalence of multiple sclerosis in England SV Ramagopalan, AE Handel, G Giovannoni, SR Siegel, GC Ebers, ... Neurology 76 (16), 1410-1414, 2011 | 116 | 2011 |
Genetic and environmental factors and the distribution of multiple sclerosis in Europe AE Handel, L Handunnetthi, G Giovannoni, GC Ebers, SV Ramagopalan European Journal of Neurology 17 (9), 1210-1214, 2010 | 99 | 2010 |
Heterogeneity in multiple sclerosis: scratching the surface of a complex disease G Disanto, AJ Berlanga, AE Handel, AE Para, AM Burrell, A Fries, ... Autoimmune diseases 2011, 2010 | 95 | 2010 |
Foxn1 regulates key target genes essential for T cell development in postnatal thymic epithelial cells S Žuklys, A Handel, S Zhanybekova, F Govani, M Keller, S Maio, ... Nature immunology 17 (10), 1206-1215, 2016 | 86 | 2016 |
The psychopathology of NMDAR-antibody encephalitis in adults: a systematic review and phenotypic analysis of individual patient data A Al-Diwani, A Handel, L Townsend, T Pollak, MI Leite, PJ Harrison, ... The Lancet Psychiatry 6 (3), 235-246, 2019 | 70 | 2019 |
Vitamin D receptor ChIP-seq in primary CD4+ cells: relationship to serum 25-hydroxyvitamin D levels and autoimmune disease AE Handel, GK Sandve, G Disanto, AJ Berlanga-Taylor, G Gallone, ... BMC medicine 11 (1), 163, 2013 | 70 | 2013 |
Assessing similarity to primary tissue and cortical layer identity in induced pluripotent stem cell-derived cortical neurons through single-cell transcriptomics AE Handel, S Chintawar, T Lalic, E Whiteley, J Vowles, A Giustacchini, ... Human molecular genetics 25 (5), 989-1000, 2016 | 68 | 2016 |
Is Lamarckian evolution relevant to medicine? AE Handel, SV Ramagopalan BMC medical genetics 11 (1), 73, 2010 | 67 | 2010 |
Epigenetic mechanisms in multiple sclerosis and the major histocompatibility complex (MHC) AM Burrell, AE Handel, SV Ramagopalan, GC Ebers, JM Morahan Discovery medicine 11 (58), 187-196, 2011 | 63 | 2011 |
Epigenetic mechanisms in multiple sclerosis and the major histocompatibility complex (MHC) AM Burrell, AE Handel, SV Ramagopalan, GC Ebers, JM Morahan Discovery medicine 11 (58), 187-196, 2011 | 63 | 2011 |
HLA-DRB1 confers increased risk of pediatric-onset MS in children with acquired demyelination G Disanto, S Magalhaes, AE Handel, KM Morrison, AD Sadovnick, ... Neurology 76 (9), 781-786, 2011 | 63 | 2011 |
Reproducibility of molecular phenotypes after long-term differentiation to human iPSC-derived neurons: a multi-site omics study V Volpato, J Smith, C Sandor, JS Ried, A Baud, A Handel, SE Newey, ... Stem cell reports 11 (4), 897-911, 2018 | 52 | 2018 |
Weekend admissions as an independent predictor of mortality: an analysis of Scottish hospital admissions AE Handel, SV Patel, A Skingsley, K Bramley, R Sobieski, ... BMJ open 2 (6), 2012 | 52 | 2012 |