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TJ Brunette
TJ Brunette
Senior Fellow in Biochemistry, University of Washington
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High-resolution comparative modeling with RosettaCM
Y Song, F DiMaio, RYR Wang, D Kim, C Miles, TJ Brunette, J Thompson, ...
Structure 21 (10), 1735-1742, 2013
11272013
Exploring the repeat protein universe through computational protein design
TJ Brunette, F Parmeggiani, PS Huang, G Bhabha, DC Ekiert, ...
Nature 528 (7583), 580-584, 2015
2862015
Programmable design of orthogonal protein heterodimers
Z Chen, SE Boyken, M Jia, F Busch, D Flores-Solis, MJ Bick, P Lu, ...
Nature 565 (7737), 106-111, 2019
1792019
Computational design of self-assembling cyclic protein homo-oligomers
JA Fallas, G Ueda, W Sheffler, V Nguyen, DE McNamara, B Sankaran, ...
Nature chemistry 9 (4), 353-360, 2017
1542017
Computational design of transmembrane pores
C Xu, P Lu, TM Gamal El-Din, XY Pei, MC Johnson, A Uyeda, MJ Bick, ...
Nature 585 (7823), 129-134, 2020
1382020
Multi-input chemical control of protein dimerization for programming graded cellular responses
GW Foight, Z Wang, CT Wei, P Jr Greisen, KM Warner, ...
Nature biotechnology 37 (10), 1209-1216, 2019
742019
Coordinated teams of reactive mobile platforms
J Sweeney, TJ Brunette, Y Yang, R Grupen
Proceedings 2002 IEEE International Conference on Robotics and Automation …, 2002
612002
Design of multi-scale protein complexes by hierarchical building block fusion
Y Hsia, R Mout, W Sheffler, NI Edman, I Vulovic, YJ Park, RL Redler, ...
Nature Communications 12 (1), 2294, 2021
562021
Guiding conformation space search with an all‐atom energy potential
TJ Brunette, O Brock
Proteins: Structure, Function, and Bioinformatics 73 (4), 958-972, 2008
542008
Modular repeat protein sculpting using rigid helical junctions
TJ Brunette, MJ Bick, JM Hansen, CM Chow, JM Kollman, D Baker
Proceedings of the National Academy of Sciences 117 (16), 8870-8875, 2020
432020
Improving protein structure prediction with model-based search
TJ Brunette, O Brock
Bioinformatics 21 (suppl_1), i66-i74, 2005
312005
De novo design of modular peptide-binding proteins by superhelical matching
K Wu, H Bai, YT Chang, R Redler, KE McNally, W Sheffler, TJ Brunette, ...
Nature 616 (7957), 581-589, 2023
182023
Elfin: An algorithm for the computational design of custom three-dimensional structures from modular repeat protein building blocks
CT Yeh, TJ Brunette, D Baker, S McIntosh-Smith, F Parmeggiani
Journal of Structural Biology 201 (2), 100-107, 2018
162018
Massively parallel determination and modeling of endonuclease substrate specificity
SB Thyme, Y Song, TJ Brunette, MD Szeto, L Kusak, P Bradley, D Baker
Nucleic acids research 42 (22), 13839-13852, 2014
162014
De novo design of obligate ABC-type heterotrimeric proteins
S Bermeo, A Favor, YT Chang, A Norris, SE Boyken, Y Hsia, HK Haddox, ...
Nature Structural & Molecular Biology 29 (12), 1266-1276, 2022
142022
De novo design of protein homodimers containing tunable symmetric protein pockets
DR Hicks, MA Kennedy, KA Thompson, M DeWitt, B Coventry, A Kang, ...
Proceedings of the National Academy of Sciences 119 (30), e2113400119, 2022
122022
Hierarchical design of multi-scale protein complexes by combinatorial assembly of oligomeric helical bundle and repeat protein building blocks
Y Hsia, R Mout, W Sheffler, NI Edman, I Vulovic, YJ Park, RL Redler, ...
bioRxiv, 2020.07. 27.221333, 2020
82020
Precisely patterned nanofibres made from extendable protein multiplexes
NP Bethel, AJ Borst, F Parmeggiani, MJ Bick, TJ Brunette, H Nguyen, ...
Nature Chemistry 15 (12), 1664-1671, 2023
62023
Repeat protein architectures
F Parmeggiani, T Brunette, PS Huang, D Baker
US Patent App. 16/060,640, 2019
32019
Predicting protein structure with guided conformation space search
O Brooke, TJ Brunette
Computer Science Department, University of Massachusetts Amherst, 2005
32005
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Artikelen 1–20