| Mechanisms of Drug Resistance in Mycobacterium tuberculosis Y Zhang, C Vilchèze, WR Jacobs JR Tuberculosis and the tubercle bacillus, 115-140, 2004 | 888 | 2004 |
| Effect of the structure of natural sterols and sphingolipids on the formation of ordered sphingolipid/sterol domains (rafts) X Xu, R Bittman, G Duportail, D Heissler, C Vilcheze, E London Journal of Biological Chemistry 276 (36), 33540-33546, 2001 | 622 | 2001 |
| Enzymic characterization of the target for isoniazid in Mycobacterium tuberculosis A Quemard, JC Sacchettini, A Dessen, C Vilcheze, R Bittman, ... Biochemistry 34 (26), 8235-8241, 1995 | 503 | 1995 |
| The mechanism of isoniazid killing: clarity through the scope of genetics C Vilchèze, WR Jacobs, Jr Annu. Rev. Microbiol. 61, 35-50, 2007 | 438 | 2007 |
| Transfer of a point mutation in Mycobacterium tuberculosis inhA resolves the target of isoniazid C Vilchèze, F Wang, M Arai, MH Hazbón, R Colangeli, L Kremer, ... Nature medicine 12 (9), 1027-1029, 2006 | 396 | 2006 |
| Pyrazinamide inhibits the eukaryotic-like fatty acid synthetase I (FASI) of Mycobacterium tuberculosis O Zimhony, JS Cox, JT Welch, C Vilcheze, WR Jacobs Nature medicine 6 (9), 1043-1047, 2000 | 387 | 2000 |
| Inactivation of the inhA-encoded fatty acid synthase II (FASII) enoyl-acyl carrier protein reductase induces accumulation of the FASI end products and cell lysis of … C Vilchèze, HR Morbidoni, TR Weisbrod, H Iwamoto, M Kuo, ... Journal of bacteriology 182 (14), 4059-4067, 2000 | 375 | 2000 |
| Mycobacterium tuberculosis is extraordinarily sensitive to killing by a vitamin C-induced Fenton reaction C Vilchèze, T Hartman, B Weinrick, WR Jacobs Jr Nature communications 4 (1), 1881, 2013 | 360 | 2013 |
| Crystal structure of the Mycobacterium tuberculosis enoyl-ACP reductase, InhA, in complex with NAD+ and a C16 fatty acyl substrate DA Rozwarski, C Vilcheze, M Sugantino, R Bittman, JC Sacchettini Journal of Biological Chemistry 274 (22), 15582-15589, 1999 | 360 | 1999 |
| Altered NADH/NAD+ Ratio Mediates Coresistance to Isoniazid and Ethionamide in Mycobacteria C Vilcheze, TR Weisbrod, B Chen, L Kremer, MH Hazbón, F Wang, ... Antimicrobial agents and chemotherapy 49 (2), 708-720, 2005 | 342 | 2005 |
| The fatty acid biosynthesis enzyme FabI plays a key role in the development of liver-stage malarial parasites M Yu, TRS Kumar, LJ Nkrumah, A Coppi, S Retzlaff, CD Li, BJ Kelly, ... Cell host & microbe 4 (6), 567-578, 2008 | 328 | 2008 |
| Auranofin exerts broad-spectrum bactericidal activities by targeting thiol-redox homeostasis MB Harbut, C Vilchèze, X Luo, ME Hensler, H Guo, B Yang, AK Chatterjee, ... Proceedings of the National Academy of Sciences 112 (14), 4453-4458, 2015 | 311 | 2015 |
| Resistance to Isoniazid and Ethionamide in Mycobacterium tuberculosis: Genes, Mutations, and Causalities C Vilchèze, WR Jacobs Jr Molecular genetics of Mycobacteria, 431-453, 2014 | 288 | 2014 |
| Overexpression of inhA, but not kasA, confers resistance to isoniazid and ethionamide in Mycobacterium smegmatis, M. bovis BCG and M. tuberculosis MH Larsen, C Vilchèze, L Kremer, GS Besra, L Parsons, M Salfinger, ... Molecular microbiology 46 (2), 453-466, 2002 | 281 | 2002 |
| Mycothiol biosynthesis is essential for ethionamide susceptibility in Mycobacterium tuberculosis C Vilchèze, Y Av‐Gay, R Attarian, Z Liu, MH Hazbón, R Colangeli, B Chen, ... Molecular microbiology 69 (5), 1316-1329, 2008 | 209 | 2008 |
| Separable roles for Mycobacterium tuberculosis ESX-3 effectors in iron acquisition and virulence JAM Tufariello, JR Chapman, CA Kerantzas, KW Wong, C Vilchèze, ... Proceedings of the National Academy of Sciences 113 (3), E348-E357, 2016 | 205 | 2016 |
| Energetics of respiration and oxidative phosphorylation in mycobacteria GM Cook, K Hards, C Vilchèze, T Hartman, M Berney Molecular Genetics of Mycobacteria, 389-409, 2014 | 198 | 2014 |
| Trichoderins, novel aminolipopeptides from a marine sponge-derived Trichoderma sp., are active against dormant mycobacteria P Pruksakorn, M Arai, N Kotoku, C Vilchèze, AD Baughn, P Moodley, ... Bioorganic & medicinal chemistry letters 20 (12), 3658-3663, 2010 | 186 | 2010 |
| Enhanced respiration prevents drug tolerance and drug resistance in Mycobacterium tuberculosis C Vilchèze, T Hartman, B Weinrick, P Jain, TR Weisbrod, LW Leung, ... Proceedings of the National Academy of Sciences 114 (17), 4495-4500, 2017 | 179 | 2017 |
| Triclosan Derivatives: Towards Potent Inhibitors of Drug‐Sensitive and Drug‐Resistant Mycobacterium tuberculosis JS Freundlich, F Wang, C Vilchèze, G Gulten, R Langley, GA Schiehser, ... ChemMedChem: Chemistry Enabling Drug Discovery 4 (2), 241-248, 2009 | 178 | 2009 |
