| PAF1 regulation of promoter-proximal pause release via enhancer activation FX Chen, P Xie, CK Collings, K Cao, Y Aoi, SA Marshall, EJ Rendleman, ... Science 357 (6357), 1294-1298, 2017 | 127 | 2017 |
| Promoter bivalency favors an open chromatin architecture in embryonic stem cells G Mas, E Blanco, C Ballaré, M Sansó, YG Spill, D Hu, Y Aoi, F Le Dily, ... Nature genetics 50 (10), 1452-1462, 2018 | 126 | 2018 |
| NELF regulates a promoter-proximal step distinct from RNA Pol II pause-release Y Aoi, ER Smith, AP Shah, EJ Rendleman, SA Marshall, AR Woodfin, ... Molecular cell 78 (2), 261-274. e5, 2020 | 121 | 2020 |
| Targeting processive transcription elongation via SEC disruption for MYC-induced cancer therapy K Liang, ER Smith, Y Aoi, KL Stoltz, H Katagi, AR Woodfin, EJ Rendleman, ... Cell 175 (3), 766-779. e17, 2018 | 89 | 2018 |
| The human integrator complex facilitates transcriptional elongation by endonucleolytic cleavage of nascent transcripts F Beckedorff, E Blumenthal, L Ferreira daSilva, Y Aoi, PR Cingaram, ... Cell reports 32 (3), 2020 | 77 | 2020 |
| Synthetic posttranslational modifications: chemical catalyst-driven regioselective histone acylation of native chromatin Y Amamoto, Y Aoi, N Nagashima, H Suto, D Yoshidome, Y Arimura, ... Journal of the American Chemical Society 139 (22), 7568-7576, 2017 | 70 | 2017 |
| LEDGF and HDGF2 relieve the nucleosome-induced barrier to transcription in differentiated cells G LeRoy, O Oksuz, N Descostes, Y Aoi, RA Ganai, HO Kara, JR Yu, ... Science Advances 5 (10), eaay3068, 2019 | 64 | 2019 |
| Potent, reversible, and specific chemical inhibitors of eukaryotic ribosome biogenesis SA Kawashima, Z Chen, Y Aoi, A Patgiri, Y Kobayashi, P Nurse, ... Cell 167 (2), 512-524. e14, 2016 | 63 | 2016 |
| SPT5 stabilization of promoter-proximal RNA polymerase II Y Aoi, YH Takahashi, AP Shah, M Iwanaszko, EJ Rendleman, NH Khan, ... Molecular cell 81 (21), 4413-4424. e5, 2021 | 54 | 2021 |
| Optimization of the analogue-sensitive Cdc2/Cdk1 mutant by in vivo selection eliminates physiological limitations to its use in cell cycle analysis Y Aoi, SA Kawashima, V Simanis, M Yamamoto, M Sato Open biology 4 (7), 140063, 2014 | 48 | 2014 |
| Synthetic chromatin acylation by an artificial catalyst system T Ishiguro, Y Amamoto, K Tanabe, J Liu, H Kajino, A Fujimura, Y Aoi, ... Chem 2 (6), 840-859, 2017 | 34 | 2017 |
| Acute perturbation strategies in interrogating RNA polymerase II elongation factor function in gene expression B Zheng, Y Aoi, AP Shah, M Iwanaszko, S Das, EJ Rendleman, D Zha, ... Genes & development 35 (3-4), 273-285, 2021 | 29 | 2021 |
| Integrator enforces the fidelity of transcriptional termination at protein-coding genes LF Dasilva, E Blumenthal, F Beckedorff, PR Cingaram, ... Science advances 7 (45), eabe3393, 2021 | 28 | 2021 |
| SPT6 functions in transcriptional pause/release via PAF1C recruitment Y Aoi, AP Shah, S Ganesan, SHA Soliman, BK Cho, YA Goo, NL Kelleher, ... Molecular cell 82 (18), 3412-3423. e5, 2022 | 27 | 2022 |
| Dissecting the first and the second meiotic divisions using a marker-less drug-hypersensitive fission yeast Y Aoi, M Sato, T Sutani, K Shirahige, TM Kapoor, SA Kawashima Cell Cycle 13 (8), 1327-1334, 2014 | 23 | 2014 |
| Cuf2 boosts the transcription of APC/C activator Fzr1 to terminate the meiotic division cycle Y Aoi, K Arai, M Miyamoto, Y Katsuta, A Yamashita, M Sato, M Yamamoto EMBO reports 14 (6), 553-560, 2013 | 19 | 2013 |
| Therapeutic targeting of transcriptional elongation in diffuse intrinsic pontine glioma H Katagi, N Takata, Y Aoi, Y Zhang, EJ Rendleman, GT Blyth, FD Eckerdt, ... Neuro-oncology 23 (8), 1348-1359, 2021 | 15 | 2021 |
| Transcriptional elongation control in developmental gene expression, aging, and disease Y Aoi, A Shilatifard Molecular cell, 2023 | 8 | 2023 |
| Enhancing HIV-1 latency reversal through regulating the elongating RNA Pol II pause-release by a small-molecule disruptor of PAF1C SHA Soliman, WJ Cisneros, M Iwanaszko, Y Aoi, S Ganesan, M Walter, ... Science Advances 9 (10), eadf2468, 2023 | 8 | 2023 |
| Somatic mutations of MLL4/COMPASS induce cytoplasmic localization providing molecular insight into cancer prognosis and treatment Z Zhao, Y Aoi, CN Philips, KA Meghani, SR Gold, Y Yu, LS John, J Qian, ... Proceedings of the National Academy of Sciences 120 (52), e2310063120, 2023 | 3 | 2023 |
Ali ShilatifardProfessor and Chairman of Biochemistry, Director of Simpson Querrey Institute for EpigeneticsVerified email at northwestern.edu
