| Lin28 promotes transformation and is associated with advanced human malignancies SR Viswanathan, JT Powers, W Einhorn, Y Hoshida, TL Ng, S Toffanin, ... Nature genetics 41 (7), 843-848, 2009 | 932 | 2009 |
| Targeting Bcr–Abl by combining allosteric with ATP-binding-site inhibitors J Zhang, FJ Adrián, W Jahnke, SW Cowan-Jacob, AG Li, RE Iacob, T Sim, ... Nature 463 (7280), 501-506, 2010 | 678 | 2010 |
| Lin28b is sufficient to drive liver cancer and necessary for its maintenance in murine models LH Nguyen, DA Robinton, MT Seligson, L Wu, L Li, D Rakheja, ... Cancer cell 26 (2), 248-261, 2014 | 218 | 2014 |
| E2F1 uses the ATM signaling pathway to induce p53 and Chk2 phosphorylation and apoptosis JT Powers, SK Hong, CN Mayhew, PM Rogers, ES Knudsen, DG Johnson Molecular Cancer Research 2 (4), 203-214, 2004 | 202 | 2004 |
| Multiple mechanisms disrupt the let-7 microRNA family in neuroblastoma JT Powers, KM Tsanov, DS Pearson, F Roels, CS Spina, R Ebright, ... Nature 535 (7611), 246-251, 2016 | 189 | 2016 |
| ATM promotes apoptosis and suppresses tumorigenesis in response to Myc RV Pusapati, RJ Rounbehler, SK Hong, JT Powers, M Yan, K Kiguchi, ... Proceedings of the National Academy of Sciences 103 (5), 1446-1451, 2006 | 171 | 2006 |
| ARF differentially modulates apoptosis induced by E2F1 and Myc JL Russell, JT Powers, RJ Rounbehler, PM Rogers, CJ Conti, ... Molecular and cellular biology 22 (5), 1360-1368, 2002 | 108 | 2002 |
| The epithelial-mesenchymal transition factor SNAIL paradoxically enhances reprogramming JJ Unternaehrer, R Zhao, K Kim, M Cesana, JT Powers, ... Stem cell reports 3 (5), 691-698, 2014 | 95 | 2014 |
| The LIN28B/let-7 axis is a novel therapeutic pathway in multiple myeloma S Manier, JT Powers, A Sacco, SV Glavey, D Huynh, MR Reagan, ... Leukemia 31 (4), 853-860, 2017 | 83 | 2017 |
| LIN28 phosphorylation by MAPK/ERK couples signalling to the post-transcriptional control of pluripotency KM Tsanov, DS Pearson, Z Wu, A Han, R Triboulet, MT Seligson, ... Nature cell biology 19 (1), 60-67, 2017 | 79 | 2017 |
| Zcchc11 uridylates mature miRNAs to enhance neonatal IGF-1 expression, growth, and survival MR Jones, MT Blahna, E Kozlowski, KY Matsuura, JD Ferrari, SA Morris, ... PLoS genetics 8 (11), e1003105, 2012 | 64 | 2012 |
| Oncogenes and the DNA damage response: Myc and E2F1 engage the ATM signaling pathway to activate p53 and induce apoptosis S Hong, RV Pusapati, JT Powers, DG Johnson Cell cycle 5 (8), 801-803, 2006 | 56 | 2006 |
| LIN28B regulates transcription and potentiates MYCN-induced neuroblastoma through binding to ZNF143 at target gene promotors T Tao, H Shi, L Mariani, BJ Abraham, AD Durbin, MW Zimmerman, ... Proceedings of the National Academy of Sciences 117 (28), 16516-16526, 2020 | 33 | 2020 |
| AP24163 Inhibits the Gatekeeper Mutant of BCR‐ABL and Suppresses In vitro Resistance M Azam, JT Powers, W Einhorn, WS Huang, WC Shakespeare, X Zhu, ... Chemical biology & drug design 75 (2), 223-227, 2010 | 26 | 2010 |
| Lin28 enhances tumorigenesis and is associated with advanced human malignancies SR Viswanathan, JT Powers, W Einhorn, Y Hoshida, T Ng, S Toffanin, ... Nature genetics 41 (7), 843, 2009 | 17 | 2009 |
| LIN28B alters ribosomal dynamics to promote metastasis in MYCN-driven malignancy P Missios, EL da Rocha, DS Pearson, J Philipp, MM Aleman, M Pirouz, ... The Journal of Clinical Investigation 131 (22), 2021 | 15 | 2021 |
| Lin28B/Let-7 axis regulates multiple myeloma proliferation by enhancing c-Myc and Ras survival pathways S Manier, JT Powers, A Sacco, MR Reagan, M Moschetta, S Glavey, ... Blood 122 (21), 273, 2013 | 3 | 2013 |
| Dissection of Bcr-abl Structural Domains Relating to Kinase Auto-Inhibition Using a Forward Mutational Screen with the Non-ATP Competitive Inhibitor GNF-2. JT Powers, M Azam, NS Gray, GQ Daley Blood 110 (11), 1021, 2007 | 2 | 2007 |
| Unsaturated fatty acid synthesis is associated with poor prognosis in pediatric neuroblastoma and is differentially regulated by MYCN and tumor suppressor microRNAs. DA Sheeter, S Garza, HG Park, NR Badi, E Espinosa, KS Kothapalli, ... | 1 | 2023 |
| Unsaturated Fatty Acid Synthesis Is Associated with Worse Survival and Is Differentially Regulated by MYCN and Tumor Suppressor microRNAs in Neuroblastoma DA Sheeter, S Garza, HG Park, LRE Benhamou, NR Badi, EC Espinosa, ... Cancers 16 (8), 1590, 2024 | | 2024 |
Mohammad AzamGeverifieerd e-mailadres voor cchmc.org
