Pharmaceuticals in the aquatic environment: a critical review of the evidence for health effects in fish J Corcoran, MJ Winter, CR Tyler Critical reviews in toxicology 40 (4), 287-304, 2010 | 684 | 2010 |
Acute and chronic effects of carrier solvents in aquatic organisms: a critical review TH Hutchinson, N Shillabeer, MJ Winter, DB Pickford Aquatic toxicology 76 (1), 69-92, 2006 | 278 | 2006 |
Comparative physiology, pharmacology and toxicology of β-blockers: mammals versus fish SF Owen, E Giltrow, DB Huggett, TH Hutchinson, JA Saye, MJ Winter, ... Aquatic Toxicology 82 (3), 145-162, 2007 | 223 | 2007 |
Validation of a larval zebrafish locomotor assay for assessing the seizure liability of early-stage development drugs MJ Winter, WS Redfern, AJ Hayfield, SF Owen, JP Valentin, ... Journal of pharmacological and toxicological methods 57 (3), 176-187, 2008 | 211 | 2008 |
A European perspective on alternatives to animal testing for environmental hazard identification and risk assessment S Scholz, E Sela, L Blaha, T Braunbeck, M Galay-Burgos, ... Regulatory toxicology and pharmacology 67 (3), 506-530, 2013 | 192 | 2013 |
Quantitative cross-species extrapolation between humans and fish: the case of the anti-depressant fluoxetine L Margiotta-Casaluci, SF Owen, RI Cumming, A De Polo, MJ Winter, ... PLoS One 9 (10), e110467, 2014 | 149 | 2014 |
High plasma concentrations of human urotensin II do not alter local or systemic hemodynamics in man IB Wilkinson, JT Affolter, SL De Haas, M Paola Pellegrini, J Boyd, ... Cardiovascular research 53 (2), 341-347, 2002 | 127 | 2002 |
DNA strand breaks and adducts determined in feral and caged chub (Leuciscus cephalus) exposed to rivers exhibiting variable water quality around Birmingham, UK MJ Winter, N Day, RA Hayes, EW Taylor, PJ Butler, JK Chipman Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 552 (1 …, 2004 | 107 | 2004 |
Complex physiological traits as biomarkers of the sub-lethal toxicological effects of pollutant exposure in fishes DJ McKenzie, E Garofalo, MJ Winter, S Ceradini, F Verweij, N Day, ... Philosophical Transactions of the Royal Society B: Biological Sciences 362 …, 2007 | 106 | 2007 |
Defining the chronic impacts of atenolol on embryo-larval development and reproduction in the fathead minnow (Pimephales promelas) MJ Winter, AD Lillicrap, JE Caunter, C Schaffner, AC Alder, M Ramil, ... Aquatic Toxicology 86 (3), 361-369, 2008 | 104 | 2008 |
Approaches to seizure risk assessment in preclinical drug discovery A Easter, ME Bell, JR Damewood Jr, WS Redfern, JP Valentin, MJ Winter, ... Drug Discovery Today 14 (17-18), 876-884, 2009 | 102 | 2009 |
Environmental endocrine disrupters dysregulate estrogen metabolism and Ca2+ homeostasis in fish and mammals via receptor-independent mechanisms CJ Kirk, L Bottomley, N Minican, H Carpenter, S Shaw, N Kohli, M Winter, ... Comparative Biochemistry and Physiology Part A: Molecular & Integrative …, 2003 | 101 | 2003 |
Validation of the use of zebrafish larvae in visual safety assessment FM Richards, WK Alderton, GM Kimber, Z Liu, I Strang, WS Redfern, ... Journal of pharmacological and toxicological methods 58 (1), 50-58, 2008 | 97 | 2008 |
No effect on central or peripheral blood pressure of systemic urotensin II infusion in humans JT Affolter, DE Newby, IB Wilkinson, MJ Winter, RJ Balment, DJ Webb British journal of clinical pharmacology 54 (6), 617-621, 2002 | 86 | 2002 |
Chronic effects assessment and plasma concentrations of the β-blocker propranolol in fathead minnows (Pimephales promelas) E Giltrow, PD Eccles, MJ Winter, PJ McCormack, M Rand-Weaver, ... Aquatic toxicology 95 (3), 195-202, 2009 | 84 | 2009 |
Ototoxin-induced cellular damage in neuromasts disrupts lateral line function in larval zebrafish LMJ Buck, MJ Winter, WS Redfern, TT Whitfield Hearing research 284 (1-2), 67-81, 2012 | 82 | 2012 |
Zebrafish assays as early safety pharmacology screens: paradigm shift or red herring? WS Redfern, G Waldron, MJ Winter, P Butler, M Holbrook, R Wallis, ... Journal of pharmacological and toxicological methods 58 (2), 110-117, 2008 | 76 | 2008 |
Plasma concentrations of arginine vasotocin and urotensin II are reduced following transfer of the euryhaline flounder (Platichthys flesus) from seawater to fresh water H Bond, MJ Winter, JM Warne, CR McCrohan, RJ Balment General and comparative endocrinology 125 (1), 113-120, 2002 | 76 | 2002 |
A multi-endpoint in vivo larval zebrafish (Danio rerio) model for the assessment of integrated cardiovascular function T Parker, PA Libourel, MJ Hetheridge, RI Cumming, TP Sutcliffe, ... Journal of pharmacological and toxicological methods 69 (1), 30-38, 2014 | 69 | 2014 |
The caudal neurosecretory system: control and function of a novel neuroendocrine system in fish MJ Winter, A Ashworth, H Bond, MJ Brierley, CR McCrohan, RJ Balment Biochemistry and Cell Biology 78 (3), 193-203, 2000 | 67 | 2000 |