Low SOX17 expression is a prognostic factor and drives transcriptional dysregulation and esophageal cancer progression IY Kuo, CC Wu, JM Chang, YL Huang, CH Lin, JJ Yan, BS Sheu, PJ Lu, ... International journal of cancer 135 (3), 563-573, 2014 | 110 | 2014 |
Small GTPase Rab37 targets tissue inhibitor of metalloproteinase 1 for exocytosis and thus suppresses tumour metastasis CH Tsai, HC Cheng, YS Wang, P Lin, J Jen, IY Kuo, YH Chang, PC Liao, ... Nature communications 5 (1), 4804, 2014 | 55 | 2014 |
Converged Rab37/IL-6 trafficking and STAT3/PD-1 transcription axes elicit an immunosuppressive lung tumor microenvironment IY Kuo, YE Yang, PS Yang, YJ Tsai, HT Tzeng, HC Cheng, WT Kuo, ... Theranostics 11 (14), 7029, 2021 | 44 | 2021 |
Prognostic CpG methylation biomarkers identified by methylation array in esophageal squamous cell carcinoma patients IY Kuo, JM Chang, SS Jiang, CH Chen, IS Chang, BS Sheu, PJ Lu, ... International journal of medical sciences 11 (8), 779, 2014 | 39 | 2014 |
Deregulation of SLIT2-mediated Cdc42 activity is associated with esophageal cancer metastasis and poor prognosis RC Tseng, JM Chang, JH Chen, WR Huang, YA Tang, IY Kuo, JJ Yan, ... Journal of Thoracic Oncology 10 (1), 189-198, 2015 | 36 | 2015 |
SOX17 overexpression sensitizes chemoradiation response in esophageal cancer by transcriptional down-regulation of DNA repair and damage response genes IY Kuo, YL Huang, CY Lin, CH Lin, WL Chang, WW Lai, YC Wang Journal of Biomedical Science 26, 1-14, 2019 | 34 | 2019 |
Rab37 mediates exocytosis of secreted frizzled-related protein 1 to inhibit Wnt signaling and thus suppress lung cancer stemness SH Cho, IY Kuo, PJF Lu, HT Tzeng, WW Lai, WC Su, YC Wang Cell death & disease 9 (9), 868, 2018 | 26 | 2018 |
Factor VII-induced microRNA-135a inhibits autophagy and is associated with poor prognosis in hepatocellular carcinoma KT Huang, IY Kuo, MC Tsai, CH Wu, LW Hsu, LY Chen, CP Kung, ... Molecular Therapy-Nucleic Acids 9, 274-283, 2017 | 25 | 2017 |
Dysregulated Kras/YY1/ZNF322A/Shh transcriptional axis enhances neo-angiogenesis to promote lung cancer progression CC Lin, IY Kuo, LT Wu, WH Kuan, SY Liao, J Jen, YE Yang, CW Tang, ... Theranostics 10 (22), 10001, 2020 | 22 | 2020 |
AKT-mediated phosphorylation enhances protein stability and transcription activity of ZNF322A to promote lung cancer progression SY Liao, IY Kuo, YT Chen, PC Liao, YF Liu, HY Wu, WW Lai, YC Wang Oncogene 38 (41), 6723-6736, 2019 | 22 | 2019 |
A six-CpG panel with DNA methylation biomarkers predicting treatment response of chemoradiation in esophageal squamous cell carcinoma WL Chang, WW Lai, IY Kuo, CY Lin, PJ Lu, BS Sheu, YC Wang Journal of gastroenterology 52, 705-714, 2017 | 21 | 2017 |
Factor VII promotes hepatocellular carcinoma progression through ERK-TSC signaling MC Tsai, KD Chen, CC Wang, KT Huang, CH Wu, IY Kuo, LY Chen, ... Cell death discovery 1 (1), 1-10, 2015 | 21 | 2015 |
Targeting protumor factor chitinase-3-like-1 secreted by Rab37 vesicles for cancer immunotherapy PS Yang, MH Yu, YC Hou, CP Chang, SC Lin, IY Kuo, PC Su, HC Cheng, ... Theranostics 12 (1), 340, 2022 | 20 | 2022 |
Recent advances in conventional and unconventional vesicular secretion pathways in the tumor microenvironment IY Kuo, CH Hsieh, WT Kuo, CP Chang, YC Wang Journal of biomedical science 29 (1), 56, 2022 | 18 | 2022 |
Network-based analysis identifies epigenetic biomarkers of esophageal squamous cell carcinoma progression CP Cheng, IY Kuo, H Alakus, KA Frazer, O Harismendy, YC Wang, ... Bioinformatics 30 (21), 3054-3061, 2014 | 16 | 2014 |
A prognostic predictor panel with DNA methylation biomarkers for early-stage lung adenocarcinoma in Asian and Caucasian populations IY Kuo, J Jen, LH Hsu, HS Hsu, WW Lai, YC Wang Journal of biomedical science 23, 1-10, 2016 | 14 | 2016 |
Coagulation factor VII and malignant progression of hepatocellular carcinoma KD Chen, KT Huang, MC Tsai, CH Wu, IY Kuo, LY Chen, TH Hu, CL Chen, ... Cell death & disease 7 (2), e2110, 2016 | 12 | 2016 |
Epigenetic silencing of AATK in acinar to ductal metaplasia in murine model of pancreatic cancer LY Ding, YC Hou, IY Kuo, TY Hsu, TC Tsai, HW Chang, WY Hsu, CC Tsao, ... Clinical Epigenetics 12, 1-18, 2020 | 11 | 2020 |
Dysregulation of SOX17/NRF2 axis confers chemoradiotherapy resistance and emerges as a novel therapeutic target in esophageal squamous cell carcinoma CH Hsieh, WH Kuan, WL Chang, IY Kuo, H Liu, DB Shieh, H Liu, B Tan, ... Journal of biomedical science 29 (1), 90, 2022 | 9 | 2022 |
Nutlin‐3 acts as a DNA methyltransferase inhibitor to sensitize esophageal cancer to chemoradiation WL Chang, CH Hsieh, IY Kuo, CH Lin, YL Huang, YC Wang Molecular Carcinogenesis 62 (2), 277-287, 2023 | 6 | 2023 |