| Genetic inactivation of the polycomb repressive complex 2 in T cell acute lymphoblastic leukemia P Ntziachristos, A Tsirigos, PV Vlierberghe, J Nedjic, T Trimarchi, ... Nature medicine 18 (2), 298-302, 2012 | 571 | 2012 |
| Exome sequencing identifies mutation in CNOT3 and ribosomal genes RPL5 and RPL10 in T-cell acute lymphoblastic leukemia K De Keersmaecker, ZK Atak, N Li, C Vicente, S Patchett, T Girardi, ... Nature genetics 45 (2), 186-190, 2013 | 445 | 2013 |
| Genome-wide RNA-mediated interference screen identifies miR-19 targets in Notch-induced T-cell acute lymphoblastic leukaemia KJ Mavrakis, AL Wolfe, E Oricchio, T Palomero, K De Keersmaecker, ... Nature cell biology 12 (4), 372-379, 2010 | 416 | 2010 |
| The genetics and molecular biology of T-ALL T Girardi, C Vicente, J Cools, K De Keersmaecker Blood, The Journal of the American Society of Hematology 129 (9), 1113-1123, 2017 | 343 | 2017 |
| Duplication of the MYB oncogene in T cell acute lymphoblastic leukemia I Lahortiga, K De Keersmaecker, P Van Vlierberghe, C Graux, ... Nature genetics 39 (5), 593-595, 2007 | 310 | 2007 |
| Deletion of the protein tyrosine phosphatase gene PTPN2 in T-cell acute lymphoblastic leukemia M Kleppe, I Lahortiga, T El Chaar, K De Keersmaecker, N Mentens, ... Nature genetics 42 (6), 530-535, 2010 | 231 | 2010 |
| Deletion of the RNA-binding proteins ZFP36L1 and ZFP36L2 leads to perturbed thymic development and T lymphoblastic leukemia DJ Hodson, ML Janas, A Galloway, SE Bell, S Andrews, CM Li, R Pannell, ... Nature immunology 11 (8), 717-724, 2010 | 223 | 2010 |
| Comprehensive analysis of transcriptome variation uncovers known and novel driver events in T-cell acute lymphoblastic leukemia Z Kalender Atak, V Gianfelici, G Hulselmans, K De Keersmaecker, ... PLoS genetics 9 (12), e1003997, 2013 | 170 | 2013 |
| Reverse engineering of TLX oncogenic transcriptional networks identifies RUNX1 as tumor suppressor in T-ALL G Della Gatta, T Palomero, A Perez-Garcia, A Ambesi-Impiombato, ... Nature medicine 18 (3), 436-440, 2012 | 170 | 2012 |
| The TLX1 oncogene drives aneuploidy in T cell transformation K De Keersmaecker, PJ Real, GD Gatta, T Palomero, ML Sulis, V Tosello, ... Nature medicine 16 (11), 1321-1327, 2010 | 170 | 2010 |
| Prognostic relevance of integrated genetic profiling in adult T-cell acute lymphoblastic leukemia P Van Vlierberghe, A Ambesi-Impiombato, K De Keersmaecker, M Hadler, ... Blood, The Journal of the American Society of Hematology 122 (1), 74-82, 2013 | 167 | 2013 |
| Loss or inhibition of stromal-derived PlGF prolongs survival of mice with imatinib-resistant Bcr-Abl1+ leukemia T Schmidt, BK Masouleh, S Loges, S Cauwenberghs, P Fraisl, C Maes, ... Cancer cell 19 (6), 740-753, 2011 | 164 | 2011 |
| Genetic insights in the pathogenesis of T-cell acute lymphoblastic leukemia K De Keersmaecker, P Marynen, J Cools haematologica 90 (8), 1116-1127, 2005 | 163 | 2005 |
| How ribosomes translate cancer SO Sulima, IJF Hofman, K De Keersmaecker, JD Dinman Cancer discovery 7 (10), 1069-1087, 2017 | 159 | 2017 |
| Hallmarks of ribosomopathies KR Kampen, SO Sulima, S Vereecke, K De Keersmaecker Nucleic acids research 48 (3), 1013-1028, 2020 | 158 | 2020 |
| Fusion of EML1 to ABL1 in T-cell acute lymphoblastic leukemia with cryptic t (9; 14)(q34; q32) K De Keersmaecker, C Graux, MD Odero, N Mentens, R Somers, ... Blood 105 (12), 4849-4852, 2005 | 155 | 2005 |
| Mutation of the receptor tyrosine phosphatase PTPRC (CD45) in T-cell acute lymphoblastic leukemia M Porcu, M Kleppe, V Gianfelici, E Geerdens, K De Keersmaecker, ... Blood, The Journal of the American Society of Hematology 119 (19), 4476-4479, 2012 | 127 | 2012 |
| Targeting nonclassical oncogenes for therapy in T-ALL PS Subramaniam, DW Whye, E Efimenko, J Chen, V Tosello, ... Cancer cell 21 (4), 459-472, 2012 | 111 | 2012 |
| The ribosomal protein gene RPL5 is a haploinsufficient tumor suppressor in multiple cancer types L Fancello, KR Kampen, IJF Hofman, J Verbeeck, K De Keersmaecker Oncotarget 8 (9), 14462, 2017 | 105 | 2017 |
| Ribosomopathies and the paradox of cellular hypo-to hyperproliferation K De Keersmaecker, SO Sulima, JD Dinman Blood, The Journal of the American Society of Hematology 125 (9), 1377-1382, 2015 | 104 | 2015 |
Jan CoolsKU Leuven, VIBVerified email at kuleuven.be
