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Bram De Wilde
Bram De Wilde
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Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer
M Peifer, L Fernández-Cuesta, ML Sos, J George, D Seidel, LH Kasper, ...
Nature genetics 44 (10), 1104-1110, 2012
14572012
Telomerase activation by genomic rearrangements in high-risk neuroblastoma
M Peifer, F Hertwig, F Roels, D Dreidax, M Gartlgruber, R Menon, ...
Nature 526 (7575), 700-704, 2015
5972015
A mechanistic classification of clinical phenotypes in neuroblastoma
S Ackermann, M Cartolano, B Hero, A Welte, Y Kahlert, A Roderwieser, ...
Science 362 (6419), 1165-1170, 2018
2692018
Emergence of New ALK Mutations at Relapse of Neuroblastoma
G Schleiermacher, N Javanmardi, V Bernard, Q Leroy, J Cappo, ...
Journal of Clinical Oncology 32 (25), 2727-2734, 2014
2232014
Targeted expression of mutated ALK induces neuroblastoma in transgenic mice
LC Heukamp, T Thor, A Schramm, K De Preter, C Kumps, B De Wilde, ...
Science translational medicine 4 (141), 141ra91-141ra91, 2012
1992012
Shallow whole genome sequencing on circulating cell-free DNA allows reliable noninvasive copy-number profiling in neuroblastoma patients
N Van Roy, M Van Der Linden, B Menten, A Dheedene, C Vandeputte, ...
Clinical Cancer Research 23 (20), 6305-6314, 2017
1192017
Accelerating drug development for neuroblastoma: summary of the second neuroblastoma drug development strategy forum from innovative therapies for children with cancer and …
L Moreno, G Barone, SG DuBois, J Molenaar, M Fischer, J Schulte, ...
European Journal of Cancer 136, 52-68, 2020
572020
The pitfalls and promise of liquid biopsies for diagnosing and treating solid tumors in children: a review
R Van Paemel, R Vlug, K De Preter, N Van Roy, F Speleman, L Willems, ...
European journal of pediatrics 179, 191-202, 2020
532020
Practical tools to implement massive parallel pyrosequencing of PCR products in next generation molecular diagnostics
K De Leeneer, J De Schrijver, L Clement, M Baetens, S Lefever, ...
PLoS One 6 (9), e25531, 2011
532011
Massively parallel sequencing for early molecular diagnosis in Leber congenital amaurosis
F Coppieters, B De Wilde, S Lefever, E De Meester, N De Rocker, ...
Genetics in medicine 14 (6), 576-585, 2012
512012
Minimally invasive classification of paediatric solid tumours using reduced representation bisulphite sequencing of cell-free DNA: a proof-of-principle study
R Van Paemel, A De Koker, C Vandeputte, L van Zogchel, T Lammens, ...
Epigenetics 16 (2), 196-208, 2021
362021
ALK positively regulates MYCN activity through repression of HBP1 expression
S Claeys, G Denecker, K Durinck, B Decaesteker, LM Mus, S Loontiens, ...
Oncogene 38 (15), 2690-2705, 2019
292019
Stage 4S neuroblastoma tumors show a characteristic DNA methylation portrait
A Decock, M Ongenaert, B De Wilde, B Brichard, R Noguera, F Speleman, ...
Epigenetics 11 (10), 761-771, 2016
292016
Methyl-CpG-binding domain sequencing reveals a prognostic methylation signature in neuroblastoma
A Decock, M Ongenaert, R Cannoodt, K Verniers, B De Wilde, G Laureys, ...
Oncotarget 7 (2), 1960, 2016
292016
Genome-wide study of the effect of blood collection tubes on the cell-free DNA methylome
R Van Paemel, A De Koker, C Caggiano, A Morlion, P Mestdagh, ...
Epigenetics 16 (7), 797-807, 2021
262021
The ETS transcription factor ETV5 is a target of activated ALK in neuroblastoma contributing to increased tumour aggressiveness
LM Mus, I Lambertz, S Claeys, C Kumps, W Van Loocke, C Van Neste, ...
Scientific Reports 10 (1), 218, 2020
262020
Target enrichment using parallel nanoliter quantitative PCR amplification
B De Wilde, S Lefever, W Dong, J Dunne, S Husain, S Derveaux, ...
BMC genomics 15, 1-14, 2014
252014
Impact of COVID-19 in paediatric early-phase cancer clinical trials in Europe: a report from the Innovative Therapies for Children with Cancer (ITCC) consortium
A Rubio-San-Simón, N André, MG Cefalo, I Aerts, A Castañeda, ...
European Journal of Cancer 141, 82-91, 2020
232020
High-throughput PCR assay design for targeted resequencing using primerXL
S Lefever, F Pattyn, B De Wilde, F Coppieters, S De Keulenaer, ...
BMC bioinformatics 18, 1-9, 2017
212017
CASP8 SNP D302H (rs1045485) is associated with worse survival in MYCN-amplified neuroblastoma patients
A Rihani, B De Wilde, F Zeka, G Laureys, N Francotte, GP Tonini, S Coco, ...
PloS one 9 (12), e114696, 2014
192014
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