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Ed C Lavelle
Ed C Lavelle
School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin
Geverifieerd e-mailadres voor tcd.ie - Homepage
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Mills. 2009. Interleukin-1 and IL-23 induce innate IL-17 production from gammadelta T cells, amplifying Th17 responses and autoimmunity
CE Sutton, SJ Lalor, CM Sweeney, CF Brereton, EC Lavelle
Immunity 31, 331-341, 0
1803*
Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes
SL Masters, A Dunne, SL Subramanian, RL Hull, GM Tannahill, FA Sharp, ...
Nature immunology 11 (10), 897-904, 2010
14182010
A crucial role for interleukin (IL)-1 in the induction of IL-17–producing T cells that mediate autoimmune encephalomyelitis
C Sutton, C Brereton, B Keogh, KHG Mills, EC Lavelle
The Journal of experimental medicine 203 (7), 1685, 2006
13042006
Autophagy controls IL-1β secretion by targeting pro-IL-1β for degradation
J Harris, M Hartman, C Roche, SG Zeng, A O'Shea, FA Sharp, EM Lambe, ...
Journal of Biological Chemistry 286 (11), 9587, 2011
9052011
Suppression of interleukin-33 bioactivity through proteolysis by apoptotic caspases
AU Lüthi, SP Cullen, EA McNeela, PJ Duriez, IS Afonina, C Sheridan, ...
Immunity 31 (1), 84-98, 2009
8252009
Uptake of particulate vaccine adjuvants by dendritic cells activates the NALP3 inflammasome
FA Sharp, D Ruane, B Claass, E Creagh, J Harris, P Malyala, M Singh, ...
Proceedings of the National Academy of Sciences 106 (3), 870-875, 2009
6492009
The vaccine adjuvant chitosan promotes cellular immunity via DNA sensor cGAS-STING-dependent induction of type I interferons
EC Carroll, L Jin, A Mori, N Munoz-Wolf, E Oleszycka, HBT Moran, ...
Immunity 44 (3), 597-608, 2016
4962016
TLR4 mediates vaccine-induced protective cellular immunity to Bordetella pertussis: role of IL-17-producing T cells
SC Higgins, AG Jarnicki, EC Lavelle, KHG Mills
The Journal of Immunology 177 (11), 7980, 2006
4922006
NLRP3 has a protective role in age-related macular degeneration through the induction of IL-18 by drusen components
SL Doyle, M Campbell, E Ozaki, RG Salomon, A Mori, PF Kenna, ...
Nature medicine 18 (5), 791-798, 2012
4612012
Mucosal vaccines—fortifying the frontiers
EC Lavelle, RW Ward
Nature Reviews Immunology 22 (4), 236-250, 2022
4122022
Pneumolysin activates the NLRP3 inflammasome and promotes proinflammatory cytokines independently of TLR4
EA McNeela, A Burke, DR Neill, C Baxter, VE Fernandes, D Ferreira, ...
PLoS pathogens 6 (11), e1001191, 2010
4092010
Toll-like receptor 4-mediated innate IL-10 activates antigen-specific regulatory T cells and confers resistance to Bordetella pertussis by inhibiting inflammatory pathology
SC Higgins, EC Lavelle, C McCann, B Keogh, E McNeela, P Byrne, ...
The Journal of Immunology 171 (6), 3119, 2003
3552003
Relative Contribution of Th1 and Th17 Cells in Adaptive Immunity to Bordetella pertussis: Towards the Rational Design of an Improved Acellular Pertussis Vaccine
PJ Ross, CE Sutton, S Higgins, AC Allen, K Walsh, A Misiak, EC Lavelle, ...
PLoS pathogens 9 (4), e1003264, 2013
3532013
Granzyme B-dependent proteolysis acts as a switch to enhance the proinflammatory activity of IL-1α
IS Afonina, GA Tynan, SE Logue, SP Cullen, M Bots, AU Lüthi, EP Reeves, ...
Molecular cell 44 (2), 265-278, 2011
3292011
The role of TLRs, NLRs, and RLRs in mucosal innate immunity and homeostasis
EC Lavelle, C Murphy, LAJ O'neill, EM Creagh
Mucosal immunology 3 (1), 17-28, 2010
3062010
Trends in vaccine adjuvants
VEJC Schijns, EC Lavelle
Expert Review of Vaccines 10 (4), 539-550, 2011
2742011
Fas/CD95-induced chemokines can serve as “find-me” signals for apoptotic cells
SP Cullen, CM Henry, CJ Kearney, SE Logue, M Feoktistova, GA Tynan, ...
Molecular cell 49 (6), 1034-1048, 2013
2372013
Immunomodulatory properties of the vaccine adjuvant alum
E Oleszycka, EC Lavelle
Current opinion in immunology 28, 1-5, 2014
2212014
Cholera toxin promotes the induction of regulatory T cells specific for bystander antigens by modulating dendritic cell activation
EC Lavelle, E McNeela, ME Armstrong, O Leavy, SC Higgins, KHG Mills
The Journal of Immunology 171 (5), 2384, 2003
2012003
Autophagy regulates IL-23 secretion and innate T cell responses through effects on IL-1 secretion
C Peral de Castro, SA Jones, C Ní Cheallaigh, CA Hearnden, L Williams, ...
The Journal of Immunology 189 (8), 4144-4153, 2012
1942012
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