Jörg Schaarschmidt
Jörg Schaarschmidt
Geverifieerd e-mailadres voor kit.edu
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Assessment of contact predictions in CASP12: co‐evolution and deep learning coming of age
J Schaarschmidt, B Monastyrskyy, A Kryshtafovych, AMJJ Bonvin
Proteins: Structure, Function, and Bioinformatics 86, 51-66, 2018
1042018
SpotOn: high accuracy identification of protein-protein interface hot-spots
IS Moreira, PI Koukos, R Melo, JG Almeida, AJ Preto, J Schaarschmidt, ...
Scientific reports 7 (1), 1-11, 2017
332017
Performance of HADDOCK and a simple contact-based protein–ligand binding affinity predictor in the D3R Grand Challenge 2
Z Kurkcuoglu, PI Koukos, N Citro, ME Trellet, J Rodrigues, IS Moreira, ...
Journal of computer-aided molecular design 32 (1), 175-185, 2018
272018
Somatic mutations in 33 benign and malignant hot thyroid nodules in children and adolescents
M Eszlinger, M Niedziela, E Typlt, H Jaeschke, S Huth, J Schaarschmidt, ...
Molecular and cellular endocrinology 393 (1-2), 39-45, 2014
242014
The DisVis and PowerFit web servers: explorative and integrative modeling of biomolecular complexes
GCP van Zundert, M Trellet, J Schaarschmidt, Z Kurkcuoglu, M David, ...
Journal of molecular biology 429 (3), 399-407, 2017
222017
Large-scale prediction of binding affinity in protein–small ligand complexes: the PRODIGY-LIG web server
A Vangone, J Schaarschmidt, P Koukos, C Geng, N Citro, ME Trellet, ...
Bioinformatics 35 (9), 1585-1587, 2019
202019
Blind prediction of homo‐and hetero‐protein complexes: The CASP13‐CAPRI experiment
MF Lensink, G Brysbaert, N Nadzirin, S Velankar, RAG Chaleil, T Gerguri, ...
Proteins: Structure, Function, and Bioinformatics 87 (12), 1200-1221, 2019
172019
Influence of the hinge region and its adjacent domains on binding and signaling patterns of the thyrotropin and follitropin receptor
J Schaarschmidt, S Huth, R Meier, R Paschke, H Jaeschke
PLoS One 9 (10), e111570, 2014
162014
The hinge region of the TSH receptor stabilizes ligand binding and determines different signaling profiles of human and bovine TSH
H Jaeschke, J Schaarschmidt, R Günther, S Mueller
Endocrinology 152 (10), 3986-3996, 2011
142011
Conversion of a decarboxylating to a non-decarboxylating glutaryl-coenzyme A dehydrogenase by site-directed mutagenesis
J Schaarschmidt, S Wischgoll, HJ Hofmann, M Boll
FEBS letters 585 (9), 1317-1321, 2011
132011
Rearrangement of the extracellular domain/extracellular loop 1 interface is critical for thyrotropin receptor activation
J Schaarschmidt, MBM Nagel, S Huth, H Jaeschke, R Moretti, V Hintze, ...
Journal of Biological Chemistry 291 (27), 14095-14108, 2016
122016
Identification of novel TSH interaction sites by systematic binding analysis of the TSHR hinge region
S Mueller, MW Szkudlinski, J Schaarschmidt, R Günther, R Paschke, ...
Endocrinology 152 (8), 3268-3278, 2011
122011
A newly discovered TSHR variant (L665F) associated with nonautoimmune hyperthyroidism in an Austrian family induces constitutive TSHR activation by steric repulsion between TM1 …
H Jaeschke, J Schaarschmidt, M Eszlinger, S Huth, R Puttinger, ...
The Journal of Clinical Endocrinology & Metabolism 99 (10), E2051-E2059, 2014
92014
Controversial constitutive TSHR activity: patients, physiology, and in vitro characterization
S Huth, H Jaeschke, J Schaarschmidt, R Paschke
Hormone and Metabolic Research 46 (07), 453-461, 2014
82014
The leipzig thyrotropin receptor mutation database: update 2012
J Lüblinghoff, IT Nebel, S Huth, H Jäschke, J Schaarschmidt, M Eszlinger, ...
European thyroid journal 1 (3), 209, 2012
82012
Late manifestation of subclinical hyperthyroidism after goitrogenesis in an index patient with a N670S TSH receptor germline mutation masquerading as TSH receptor antibody …
J Schaarschmidt, S Paschke, M Özerden, H Jäschke, S Huth, M Eszlinger, ...
Hormone and Metabolic Research 44 (13), 962-965, 2012
72012
Natural helix 9 mutants of PPARγ differently affect its transcriptional activity
MF Broekema, MPG Massink, C Donato, J de Ligt, J Schaarschmidt, ...
Molecular metabolism 20, 115-127, 2019
42019
An overview of data‐driven HADDOCK strategies in CAPRI rounds 38‐45
PI Koukos, J Roel‐Touris, F Ambrosetti, C Geng, J Schaarschmidt, ...
Proteins: Structure, Function, and Bioinformatics, 2020
12020
West-Life: A Virtual Research Environment for structural biology
C Morris, P Andreetto, L Banci, AMJJ Bonvin, G Chojnowski, L del Cano, ...
Journal of Structural Biology: X 1, 100006, 2019
12019
Substrate specificity of the pyrophosphohydrolase LpxH determines the asymmetry of Bordetella pertussis lipid A
J Arenas, E Pupo, E de Jonge, J Pérez-Ortega, J Schaarschmidt, ...
Journal of Biological Chemistry 294 (20), 7982-7989, 2019
2019
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Artikelen 1–20