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Yuh Min Chook
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Karyopherins and nuclear import
YM Chook, G Blobel
Current opinion in structural biology 11 (6), 703-715, 2001
6862001
Rules for nuclear localization sequence recognition by karyopherinβ2
BJ Lee, AE Cansizoglu, KE Süel, TH Louis, Z Zhang, YM Chook
Cell 126 (3), 543-558, 2006
6572006
Structure of the nuclear transport complex karyopherin-β2–Ran GppNHp
YM Chook, G Blobel
Nature 399 (6733), 230-237, 1999
4831999
Nuclear import by karyopherin-βs: recognition and inhibition
YM Chook, KE Süel
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1813 (9), 1593-1606, 2011
4572011
Nuclear-import receptors reverse aberrant phase transitions of RNA-binding proteins with prion-like domains
L Guo, HJ Kim, H Wang, J Monaghan, F Freyermuth, JC Sung, ...
Cell 173 (3), 677-692. e20, 2018
4192018
Selective inhibitors of nuclear export show that CRM1/XPO1 is a target in chronic lymphocytic leukemia
R Lapalombella, Q Sun, K Williams, L Tangeman, S Jha, Y Zhong, ...
Blood, The Journal of the American Society of Hematology 120 (23), 4621-4634, 2012
3652012
Structural basis for leucine-rich nuclear export signal recognition by CRM1
X Dong, A Biswas, KE Süel, LK Jackson, R Martinez, H Gu, YM Chook
Nature 458 (7242), 1136-1141, 2009
3502009
Nuclear import receptor inhibits phase separation of FUS through binding to multiple sites
T Yoshizawa, R Ali, J Jiou, HYJ Fung, KA Burke, SJ Kim, Y Lin, ...
Cell 173 (3), 693-705. e22, 2018
2892018
Crystal structures of the monofunctional chorismate mutase from Bacillus subtilis and its complex with a transition state analog.
YM Chook, H Ke, WN Lipscomb
Proceedings of the National Academy of Sciences 90 (18), 8600-8603, 1993
2761993
Recognition of nuclear targeting signals by Karyopherin-β proteins
D Xu, A Farmer, YM Chook
Current opinion in structural biology 20 (6), 782-790, 2010
2522010
Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1
Q Sun, YP Carrasco, Y Hu, X Guo, H Mirzaei, J MacMillan, YM Chook
Proceedings of the National Academy of Sciences 110 (4), 1303-1308, 2013
2392013
The monofunctional chorismate mutase from Bacillus subtilis: structure determination of chorismate mutase and its complexes with a transition state analog and prephenate, and …
YM Chook, JV Gray, H Ke, WN Lipscomb
Journal of molecular biology 240 (5), 476-500, 1994
2271994
Antileukemic activity of nuclear export inhibitors that spare normal hematopoietic cells
J Etchin, Q Sun, A Kentsis, A Farmer, ZC Zhang, T Sanda, MR Mansour, ...
Leukemia 27 (1), 66-74, 2013
2012013
NESdb: a database of NES-containing CRM1 cargoes
D Xu, NV Grishin, YM Chook
Molecular biology of the cell 23 (18), 3673-3676, 2012
1892012
Structure-based design of a pathway-specific nuclear import inhibitor
AE Cansizoglu, BJ Lee, ZC Zhang, BMA Fontoura, YM Chook
Nature structural & molecular biology 14 (5), 452-454, 2007
1812007
Sequence and structural analyses of nuclear export signals in the NESdb database
D Xu, A Farmer, G Collett, NV Grishin, YM Chook
Molecular biology of the cell 23 (18), 3677-3693, 2012
1702012
Nuclear localization signals for four distinct karyopherin-β nuclear import systems
M Soniat, YM Chook
Biochemical Journal 468 (3), 353-362, 2015
1662015
Structural and energetic basis of ALS-causing mutations in the atypical proline–tyrosine nuclear localization signal of the Fused in Sarcoma protein (FUS)
ZC Zhang, YM Chook
Proceedings of the National Academy of Sciences 109 (30), 12017-12021, 2012
1612012
Atomic basis of CRM1-cargo recognition, release and inhibition
HYJ Fung, YM Chook
Seminars in cancer biology 27, 52-61, 2014
1532014
LocNES: a computational tool for locating classical NESs in CRM1 cargo proteins
D Xu, K Marquis, J Pei, SC Fu, T Cağatay, NV Grishin, YM Chook
Bioinformatics 31 (9), 1357-1365, 2015
1482015
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