Charalampos A. Lazaris
Charalampos A. Lazaris
Whitehead Institute for Biomedical Research
Geverifieerd e-mailadres voor wi.mit.edu - Homepage
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FBXW7 modulates cellular stress response and metastatic potential through HSF1 post-translational modification
N Kourtis, RS Moubarak, B Aranda-Orgilles, K Lui, IT Aydin, T Trimarchi, ...
Nature cell biology 17 (3), 322-332, 2015
842015
Stratification of TAD boundaries reveals preferential insulation of super-enhancers by strong boundaries
Y Gong, C Lazaris, T Sakellaropoulos, A Lozano, P Kambadur, ...
Nature communications 9 (1), 1-12, 2018
602018
Low-grade astrocytoma mutations in IDH1, P53, and ATRX cooperate to block differentiation of human neural stem cells via repression of SOX2
AS Modrek, D Golub, T Khan, D Bready, J Prado, C Bowman, J Deng, ...
Cell reports 21 (5), 1267-1280, 2017
582017
HiC-bench: comprehensive and reproducible Hi-C data analysis designed for parameter exploration and benchmarking
C Lazaris, S Kelly, P Ntziachristos, I Aifantis, A Tsirigos
BMC genomics 18 (1), 1-16, 2017
462017
RNA-Mediated Feedback Control of Transcriptional Condensates
JE Henninger, O Oksuz, K Shrinivas, I Sagi, G LeRoy, MM Zheng, ...
Cell, 2020
452020
Oncogenic hijacking of the stress response machinery in T cell acute lymphoblastic leukemia
N Kourtis, C Lazaris, K Hockemeyer, JC Balandrán, AR Jimenez, ...
Nature medicine 24 (8), 1157-1166, 2018
412018
The ubiquitin ligase Huwe1 regulates the maintenance and lymphoid commitment of hematopoietic stem cells
B King, F Boccalatte, K Moran-Crusio, E Wolf, J Wang, C Kayembe, ...
Nature immunology 17 (11), 1312-1321, 2016
402016
Role of dysregulated cytokine signaling and bacterial triggers in the pathogenesis of cutaneous T-cell lymphoma
MH Fanok, A Sun, LK Fogli, V Narendran, M Eckstein, K Kannan, ...
Journal of Investigative Dermatology 138 (5), 1116-1125, 2018
392018
Regulation of transcriptional elongation in pluripotency and cell differentiation by the PHD-finger protein Phf5a
A Strikoudis, C Lazaris, T Trimarchi, ALG Neto, Y Yang, P Ntziachristos, ...
Nature cell biology 18 (11), 1127-1138, 2016
352016
Three-dimensional chromatin landscapes in T cell acute lymphoblastic leukemia
A Kloetgen, P Thandapani, P Ntziachristos, Y Ghebrechristos, S Nomikou, ...
Nature Genetics, 2020
332020
Opposing functions of H2BK120 ubiquitylation and H3K79 methylation in the regulation of pluripotency by the Paf1 complex
A Strikoudis, C Lazaris, P Ntziachristos, A Tsirigos, I Aifantis
Cell cycle 16 (24), 2315-2322, 2017
72017
Extent and context dependence of pleiotropy revealed by high-throughput single-cell phenotyping
KA Geiler-Samerotte, S Li, C Lazaris, A Taylor, N Ziv, GC Ramjeawan, ...
PLOS Biology 18 (8), e3000836, 2020
62020
On epigenetic plasticity and genome topology
C Lazaris, I Aifantis, A Tsirigos
Trends in cancer 6 (3), 177-180, 2020
42020
Dynamic 3D chromosomal landscapes in acute leukemia
A Kloetgen, P Thandapani, P Ntziachristos, Y Ghebrechristos, S Nomikou, ...
bioRxiv, 724427, 2019
42019
Stratification of TAD boundaries identified in reproducible Hi-C contact matrices reveals preferential insulation of super-enhancers by strong boundaries
Y Gong, C Lazaris, T Sakellaropoulos, A Lozano, P Kambadur, ...
bioRxiv, 141481, 2017
22017
Tumor immune infiltration estimated from gene expression profiles predicts colorectal cancer relapse
Y Kamal, D Dwan, HJ Hoehn, R Sanz-Pamplona, MH Alonso, V Moreno, ...
OncoImmunology 10 (1), 1862529, 2021
12021
Dynamic 3d chromosomal landscapes in acute leukemia
P Thandapani, A Kloetgen, C Lazaris, X Chen, P Ntziachristos, A Tsirigos, ...
Cancer Research 78 (13 Supplement), 2998-2998, 2018
12018
The ubiquitin ligase HUWE1 regulates hematopoietic stem cell maintenance and lymphoid commitment
B King, F Boccalatte, K Moran-Crusio, E Wolf, J Wang, C Kayembe, ...
Nature immunology 17 (11), 1312, 2016
12016
Genetic Alterations of Topologically Associating Domain (TAD) Boundaries in Cancer
C Lazaris
New York University, ProQuest Dissertations Publishing, 2018. 10640945, 2018
2018
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Artikelen 1–19