CRISPR screens in cancer spheroids identify 3D growth-specific vulnerabilities K Han, SE Pierce, A Li, K Spees, GR Anderson, JA Seoane, YH Lo, ... Nature 580 (7801), 136-141, 2020 | 226 | 2020 |
A genome-wide atlas of co-essential modules assigns function to uncharacterized genes M Wainberg, RA Kamber, A Balsubramani, RM Meyers, ... Nature genetics 53 (5), 638-649, 2021 | 109 | 2021 |
Sequence comparison of prefrontal cortical brain transcriptome from a tame and an aggressive silver fox (Vulpes vulpes) AV Kukekova, JL Johnson, C Teiling, L Li, IN Oskina, AV Kharlamova, ... BMC genomics 12, 1-20, 2011 | 67 | 2011 |
Systematic identification of regulators of oxidative stress reveals non-canonical roles for peroxisomal import and the pentose phosphate pathway MM Dubreuil, DW Morgens, K Okumoto, M Honsho, K Contrepois, ... Cell reports 30 (5), 1417-1433. e7, 2020 | 57 | 2020 |
A ZDHHC5-GOLGA7 protein acyltransferase complex promotes nonapoptotic cell death PJ Ko, C Woodrow, MM Dubreuil, BR Martin, R Skouta, MC Bassik, ... Cell chemical biology 26 (12), 1716-1724. e9, 2019 | 42 | 2019 |
Retro-2 protects cells from ricin toxicity by inhibiting ASNA1-mediated ER targeting and insertion of tail-anchored proteins DW Morgens, C Chan, AJ Kane, NR Weir, A Li, MM Dubreuil, CK Tsui, ... Elife 8, e48434, 2019 | 17 | 2019 |
The expanding CRISPR toolbox J Tycko, GT Hess, EE Jeng, M Dubreuil, MC Bassik Nature Methods, 2017 | 6 | 2017 |
Coexpression of MHC class I–restricted neoTCRs and ectopic CD8 receptors in precision genome engineered CD4 T cells significantly potentiates antigen-specific effector functions B Sennino, A Conroy, B Purandare, K Jacoby, O Dalmas, S Peng, ... Cancer Research 80 (16), 2020 | 1 | 2020 |
COMPOSITIONS AND METHODS FOR THE TREATMENT OF CANCER USING A TGFßRII ENGINEERED T CELL THERAPY JD Gagnon, B Sennino, S Mandl-Cashman, K Jacoby, W Lu, MM Dubreuil, ... US Patent App. 18/319,743, 2024 | | 2024 |
Compositions and methods for the treatment of cancer using next generation engineered t cell therapy M Mass, W Lu, K Jacoby, MM Dubreuil, B Sennino, S Mandl-Cashman, ... US Patent App. 18/306,927, 2023 | | 2023 |
Compositions and methods for the treatment of cancer using a cd8 engineered t cell therapy B Sennino, K Jacoby, S Mandl-Cashman, MM Dubreuil, J Gagnon, ... US Patent App. 17/691,565, 2022 | | 2022 |
Non-viral precision genome engineering enables personalized adoptive neoTCR T cell therapy for cancer including multiple additional edits that improve the activity of neoTCR T … CW Tran, K Lee, B Purandare, J Byers, MM Dubreuil, W Lu, M Mass, ... Cancer Research 82 (12_Supplement), 2829-2829, 2022 | | 2022 |
Compositions and methods for the treatment of cancer using a CD8 engineered T cell therapy B Sennino, K Jacoby, S Mandl-Cashman, MM Dubreuil, J Gagnon, ... US Patent 11,304,978, 2022 | | 2022 |
Single-step precision genome engineering platform enables versatile generation of personalized (neoTCR) adoptive cell therapy T cells with supplementary anti-tumor attributes MM Dubreuil, CW Tran, B Purandare, W Lu, J Byers, M Mass, K Jacoby, ... Cancer Research 81 (13_Supplement), 1526-1526, 2021 | | 2021 |
Compositions and methods for the treatment of cancer using a tet2 engineered t cell therapy B Sennino, K Jacoby, S Mandl-Cashman, MM Dubreuil, J Gagnon, ... US Patent App. 17/099,140, 2021 | | 2021 |
Compositions and methods for the treatment of cancer using a cdb engineered t cell therapy B Sennino, K Jacoby, S Mandl-Cashman, MM DUBREUIL, J Gagnon, ... | | 2020 |
A Protein Acyltransferase Complex Promotes Nonapoptotic Cell Death PJ Ko, C Woodrow, M Dubreuil, B Martin, R Skouta, M Bassik, SJ Dixon Available at SSRN 3404260, 2019 | | 2019 |