| Use of zebrafish in drug discovery toxicology S Cassar, I Adatto, JL Freeman, JT Gamse, I Iturria, C Lawrence, ... Chemical research in toxicology 33 (1), 95-118, 2019 | 419 | 2019 |
| Species comparison and pharmacological characterization of rat and human CB2 cannabinoid receptors S Mukherjee, M Adams, K Whiteaker, A Daza, K Kage, S Cassar, M Meyer, ... European journal of pharmacology 505 (1-3), 1-9, 2004 | 141 | 2004 |
| Positive allosteric modulation of the α7 nicotinic acetylcholine receptor: ligand interactions with distinct binding sites and evidence for a prominent role of the M2-M3 segment D Bertrand, S Bertrand, S Cassar, E Gubbins, J Li, M Gopalakrishnan Molecular pharmacology 74 (5), 1407-1416, 2008 | 132 | 2008 |
| Molecular determinants of species-specific activation or blockade of TRPA1 channels J Chen, XF Zhang, ME Kort, JR Huth, C Sun, LJ Miesbauer, SC Cassar, ... Journal of Neuroscience 28 (19), 5063-5071, 2008 | 125 | 2008 |
| Convergent origins of ambrosia fungi S Cassar, M Blackwell Mycologia 88 (4), 596-601, 1996 | 111 | 1996 |
| Molecular modeling and pharmacological analysis of species-related histamine H3 receptor heterogeneity BB Yao, CW Hutchins, TL Carr, S Cassar, JN Masters, YL Bennani, ... Neuropharmacology 44 (6), 773-786, 2003 | 91 | 2003 |
| Use of a fluorescent imaging plate reader-based calcium assay to assess pharmacological differences between the human and rat vanilloid receptor DG Witte, SC Cassar, JN Masters, T Esbenshade, AA Hancock Journal of biomolecular screening 7 (5), 466-475, 2002 | 68 | 2002 |
| Utility of large-scale transiently transfected cells for cell-based high-throughput screens to identify transient receptor potential channel A1 (TRPA1) antagonists J Chen, MR Lake, RS Sabet, W Niforatos, SD Pratt, SC Cassar, J Xu, ... SLAS Discovery 12 (1), 61-69, 2007 | 53 | 2007 |
| Cloning and pharmacological characterization of the monkey histamine H3 receptor BB Yao, R Sharma, S Cassar, TA Esbenshade, AA Hancock European journal of pharmacology 482 (1-3), 49-60, 2003 | 47 | 2003 |
| CYP3A5 Genotype has a Dose‐dependent Effect on ABT‐773 Plasma Levels DA Katz, DR Grimm, SC Cassar, MC Gentile, X Ye, MJ Rieser, EF Gordon, ... Clinical Pharmacology & Therapeutics 75 (6), 516-528, 2004 | 46 | 2004 |
| Isoindolinone kinase inhibitors M Matulenko, T Jinkerson, BS Brown, W Braje, M Curtin, HR Heyman, ... US Patent App. 12/938,915, 2011 | 42 | 2011 |
| A multi-institutional study benchmarking the zebrafish developmental assay for prediction of embryotoxic plasma concentrations from rat embryo–fetal development studies S Cassar, M Beekhuijzen, B Beyer, R Chapin, M Dorau, A Hoberman, ... Reproductive Toxicology 86, 33-44, 2019 | 33 | 2019 |
| Detection of multiple H3 receptor affinity states utilizing [3H] A-349821, a novel, selective, non-imidazole histamine H3 receptor inverse agonist radioligand DG Witte, BB Yao, TR Miller, TL Carr, S Cassar, R Sharma, R Faghih, ... British journal of pharmacology 148 (5), 657, 2006 | 33 | 2006 |
| Pharmacological modulation of brain activity in a preclinical model of osteoarthritis J Upadhyay, SJ Baker, R Rajagovindan, M Hart, P Chandran, BA Hooker, ... Neuroimage 64, 341-355, 2013 | 27 | 2013 |
| Measuring drug absorption improves interpretation of behavioral responses in a larval zebrafish locomotor assay for predicting seizure liability S Cassar, L Breidenbach, A Olson, X Huang, H Britton, C Woody, ... Journal of Pharmacological and Toxicological Methods 88, 56-63, 2017 | 26 | 2017 |
| Importance of M2–M3 loop in governing properties of genistein at the α7 nicotinic acetylcholine receptor inferred from α7/5-HT3A chimera JH Grønlien, H Ween, K Thorin-Hagene, S Cassar, J Li, CA Briggs, ... European journal of pharmacology 647 (1-3), 37-47, 2010 | 25 | 2010 |
| Association of Catsper1 or-2 with Cav3. 3 leads to suppression of T-type calcium channel activity D Zhang, J Chen, A Saraf, S Cassar, P Han, JC Rogers, JD Brioni, ... Journal of biological chemistry 281 (31), 22332-22341, 2006 | 23 | 2006 |
| From the cover: inhibitors of nicotinamide phosphoribosyltransferase cause retinal damage in larval zebrafish S Cassar, C Dunn, A Olson, W Buck, S Fossey, MF Ramos, P Sancheti, ... Toxicological Sciences 161 (2), 300-309, 2018 | 21 | 2018 |
| A novel potassium channel encoded by Ectocarpus siliculosus virus J Chen, SC Cassar, D Zhang, M Gopalakrishnan Biochemical and biophysical research communications 326 (4), 887-893, 2005 | 19 | 2005 |
| Tissue specific expression of alternative splice forms of human cyclic nucleotide gated channel subunit CNGA3 SC Cassar, J Chen, D Zhang, M Gopalakrishnan Mol Vis 10, 808-813, 2004 | 17 | 2004 |
