Amee J George
Amee J George
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The renin–angiotensin system and cancer: old dog, new tricks
AJ George, WG Thomas, RD Hannan
Nature Reviews Cancer 10 (11), 745-759, 2010
ATRX interacts with H3. 3 in maintaining telomere structural integrity in pluripotent embryonic stem cells
LH Wong, JD McGhie, M Sim, MA Anderson, S Ahn, RD Hannan, ...
Genome research 20 (3), 351-360, 2010
AKT induces senescence in human cells via mTORC1 and p53 in the absence of DNA damage: implications for targeting mTOR during malignancy
MV Astle, KM Hannan, PY Ng, RS Lee, AJ George, AK Hsu, Y Haupt, ...
Oncogene 31 (15), 1949-1962, 2012
The β-amyloid protein of Alzheimer's disease increases neuronal CRMP-2 phosphorylation by a Rho-GTP mechanism
S Petratos, QX Li, AJ George, X Hou, ML Kerr, SE Unabia, I Hatzinisiriou, ...
Brain 131 (1), 90-108, 2007
The nucleolus: an emerging target for cancer therapy
N Hein, KM Hannan, AJ George, E Sanij, RD Hannan
Trends in molecular medicine 19 (11), 643-654, 2013
APP intracellular domain is increased and soluble Aβ is reduced with diet-induced hypercholesterolemia in a transgenic mouse model of Alzheimer disease
AJ George, RM Holsinger, CA McLean, KM Laughton, K Beyreuther, ...
Neurobiology of disease 16 (1), 124-132, 2004
Decreased phosphatidylethanolamine binding protein expression correlates with Aβ accumulation in the Tg2576 mouse model of Alzheimer's disease
AJ George, RM Holsinger, CA McLean, SS Tan, HS Scott, T Cardamone, ...
Neurobiology of aging 27 (4), 614-623, 2006
Combination therapy targeting ribosome biogenesis and mRNA translation synergistically extends survival in MYC-driven lymphoma
JR Devlin, KM Hannan, N Hein, C Cullinane, E Kusnadi, PY Ng, ...
Cancer discovery 6 (1), 59-70, 2016
Inhibition of RNA polymerase I transcription initiation by CX-5461 activates non-canonical ATM/ATR signaling
J Quin, KT Chan, JR Devlin, DP Cameron, J Diesch, C Cullinane, J Ahern, ...
Oncotarget 7 (31), 49800-49818, 2016
Unravelling the molecular complexity of GPCR‐mediated EGFR transactivation using functional genomics approaches
AJ George, RD Hannan, WG Thomas
The FEBS journal 280 (21), 5258-5268, 2013
The angiotensin receptor blocker, Losartan, inhibits mammary tumor development and progression to invasive carcinoma
R Coulson, SH Liew, AA Connelly, NS Yee, S Deb, B Kumar, AC Vargas, ...
Oncotarget 8 (12), 18640, 2017
A serial analysis of gene expression profile of the Alzheimer’s disease Tg2576 mouse model
AJ George, L Gordon, T Beissbarth, I Koukoulas, RMD Holsinger, ...
Neurotoxicity research 17 (4), 360-379, 2010
Inhibition of Pol I transcription treats murine and human AML by targeting the leukemia-initiating cell population
N Hein, DP Cameron, KM Hannan, NYN Nguyen, CY Fong, J Sornkom, ...
Blood 129 (21), 2882-2895, 2017
New roles for the nucleolus in health and disease
L N˙˝ez VillacÝs, MS Wong, LL Ferguson, N Hein, AJ George, ...
Bioessays 40 (5), 1700233, 2018
A functional siRNA screen identifies genes modulating angiotensin II-mediated EGFR transactivation
AJ George, BW Purdue, CM Gould, DW Thomas, Y Handoko, H Qian, ...
J Cell Sci 126 (23), 5377-5390, 2013
Self-reverting mutations partially correct the blood phenotype in a Diamond Blackfan Anemia patient.
P Venugopal, S Moore, DM Lawrence, AJ George, RD Hannan, SC Bray, ...
Haematologica, 2017
Glucocorticoids improve erythroid progenitor maintenance and dampen Trp53 response in a mouse model of Diamond–Blackfan anaemia
SE Sj÷gren, K Siva, S Soneji, AJ George, M Winkler, P Jaako, ...
British journal of haematology 171 (4), 517-529, 2015
A functional genetic screen defines the AKT-induced senescence signaling network
KT Chan, S Blake, H Zhu, J Kang, AS Trigos, PB Madhamshettiwar, ...
Cell Death & Differentiation 27 (2), 725-741, 2020
A dual antigen ELISA allows the assessment of SARS-CoV-2 antibody seroprevalence in a low transmission setting
S Hicks, K Pohl, T Neeman, H McNamara, K Parsons, JS He, S Ali, ...
medRxiv, 2020
Combining high-content imaging and phenotypic classification analysis of senescence-associated beta-galactosidase staining to identify regulators of oncogene-induced senescence
KT Chan, L Paavolainen, KM Hannan, AJ George, RD Hannan, ...
ASSAY and Drug Development Technologies 14 (7), 416-428, 2016
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Artikelen 1–20