Matthew J. Emmett, MD, PhD
Matthew J. Emmett, MD, PhD
Hematology/Oncology Fellow, Dana-Farber Cancer Institute, Mass General Brigham
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Discrete functions of nuclear receptor Rev-erbα couple metabolism to the clock
Y Zhang*, B Fang*, MJ Emmett, M Damle, Z Sun, D Feng, SM Armour, ...
Science, 2015
The nuclear receptor Rev-erbα controls circadian thermogenic plasticity.
Z Gerhart-Hines, D Feng*, MJ Emmett*, LJ Everett, E Loro, ER Briggs, ...
Nature 503 (7476), 410-413, 2013
De Novo Formation of Insulin-Producing “Neo-β Cell Islets” from Intestinal Crypts
YJ Chen, Finkbeiner SR, D Weinblatt, MJ Emmett, F Tameire, M Yousefi, ...
Cell Reports 6 (6), 1-13, 2014
Histone deacetylase 3 prepares brown adipose tissue for acute thermogenic challenge
MJ Emmett, HW Lim, J Jager, HJ Richter, M Adlanmerini, LC Peed, ...
Nature 546 (7659), 544-548, 2017
Genetic Variation Determines PPARg Function and Anti-diabetic Drug Response In Vivo
RE Soccio, ER Chen, SR Rajapurkar, P Safabakhsh, JM Marinis, ...
Cell 162 (1), 33-34, 2015
LIN28B promotes growth and tumorigenesis of the intestinal epithelium via Let-7
BB Madison, Q Liu, X Zhong, CM Hahn, N Lin, MJ Emmett, BZ Stanger, ...
Genes Dev. 27 (20), 2233-2245, 2013
Integrative regulation of physiology by histone deacetylase 3
MJ Emmett, MA Lazar
Nature Reviews Molecular Cell Biology 20 (2), 102-115, 2019
SR9009 has REV-ERB–independent effects on cell proliferation and metabolism
P Dierickx, MJ Emmett, C Jiang, K Uehara, M Liu, M Adlanmerini, L MA
Proceedings of the National Academy of Sciences, 2019
Targeting PPARγ in the epigenome rescues genetic metabolic defects in mice
RE Soccio, Z Li, ER Chen, YH Foong, B Kiara K., JR Dispirito, SE Mullican, ...
The Journal of Clinical Investigation 127 (3), 2017
Lactate dehydrogenase C produces S-2-hydroxyglutarate in mouse testis
X Teng, MJ Emmett, MA Lazar, E Goldberg, JD Rabinowitz
ACS Chemical Biology 11 (9), 2420-2427, 2016
The role of mouse Akt2 in insulin-dependent suppression of adipocyte lipolysis in vivo.
S Koren, LM DiPilato, MJ Emmett, AL Shearin, Q Chu, B Monks, ...
Diabetologia 58 (5), 1063-1070, 2015
Early B Cell Factor Activity Controls Developmental and Adaptive Thermogenic Gene Programming in Adipocytes
AR Angueira, SN Shapira, J Ishibashi, S Sampat, J Sostre-Colón, ...
Cell Reports 30 (9), 2869-2878. e4, 2020
Ascites and resistance to immune checkpoint inhibition in dMMR/MSI-H metastatic colorectal and gastric cancers
G Fucà, R Cohen, S Lonardi, K Shitara, ME Elez, M Fakih, J Chao, ...
Journal for Immunotherapy of Cancer 10 (2), 2022
β-Adrenergic receptors control brown adipose UCP-1 tone and cold response without affecting its circadian rhythmicity
M Razzoli, MJ Emmett, MA Lazar, A Bartolomucci
The FASEB Journal, fj. 201800452R, 2018
Control of brown adipose thermogenesis by a cold-inducible, circadian mitochondrial transporter
I Karavaeva, T Ma, EG Sustarsic, MJ Emmett, H Majd, MP Jedrychowski, ...
Biochimica et Biophysica Acta (BBA) - Bioenergetics 1859 (Supplement), e94, 2018
Epidermal Growth Factor Receptor Inhibition in Epidermal Growth Factor Receptor–Amplified Gastroesophageal Cancer: Retrospective Global Experience
SB Maron, S Moya, F Morano, MJ Emmett, JF Chou, S Sabwa, H Walch, ...
Journal of Clinical Oncology 40 (22), 2458-2467, 2022
Global-run on sequencing identifies Gm11967 as an Akt-dependent long noncoding RNA involved in insulin sensitivity
D Santoleri, HW Lim, MJ Emmett, J Stoute, MJ Gavin, J Sostre-Colón, ...
iScience, 104410, 2022
Case 18-2021: An 81-Year-Old Man with Cough, Fever, and Shortness of Breath
KA Hibbert, RJ Goiffon, AE Fogerty
New England Journal of Medicine 384 (24), 2332-2340, 2021
Balanced control of thermogenesis by nuclear receptor corepressors in brown adipose tissue
HJ Richter, AK Hauck, K Batmanov, SI Inoue, BN So, M Kim, MJ Emmett, ...
Proceedings of the National Academy of Sciences 119 (33), e2205276119, 2022
Esophageal and gastric cancer
M Emmett, A Mehta, S Klempner
Genomic and Precision Medicine, 255-275, 2022
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