Evaluating the analytical validity of circulating tumor DNA sequencing assays for precision oncology IW Deveson, B Gong, K Lai, JS LoCoco, TA Richmond, J Schageman, ... Nature biotechnology 39 (9), 1115-1128, 2021 | 148 | 2021 |
A network pharmacology study of Chinese medicine QiShenYiQi to reveal its underlying multi-compound, multi-target, multi-pathway mode of action X Li, L Wu, W Liu, Y Jin, Q Chen, L Wang, X Fan, Z Li, Y Cheng PloS one 9 (5), e95004, 2014 | 132 | 2014 |
Comparing SVM and ANN based machine learning methods for species identification of food contaminating beetles H Bisgin, T Bera, H Ding, HG Semey, L Wu, Z Liu, AE Barnes, DA Langley, ... Scientific reports 8 (1), 6532, 2018 | 119 | 2018 |
Toward best practice in cancer mutation detection with whole-genome and whole-exome sequencing W Xiao, L Ren, Z Chen, LT Fang, Y Zhao, J Lack, M Guan, B Zhu, ... Nature biotechnology 39 (9), 1141-1150, 2021 | 80 | 2021 |
Drug-induced liver injury severity and toxicity (DILIst): binary classification of 1279 drugs by human hepatotoxicity S Thakkar, T Li, Z Liu, L Wu, R Roberts, W Tong Drug discovery today 25 (1), 201-208, 2020 | 80 | 2020 |
Identifying roles of “Jun-Chen-Zuo-Shi” component herbs of QiShenYiQi formula in treating acute myocardial ischemia by network pharmacology L Wu, Y Wang, Z Li, B Zhang, Y Cheng, X Fan Chinese medicine 9, 1-9, 2014 | 60 | 2014 |
Comprehensive assessments of RNA-seq by the SEQC consortium: FDA-led efforts advance precision medicine J Xu, B Gong, L Wu, S Thakkar, H Hong, W Tong Pharmaceutics 8 (1), 8, 2016 | 57 | 2016 |
Multiple microRNAs function as self-protective modules in acetaminophen-induced hepatotoxicity in humans D Yu, L Wu, P Gill, WH Tolleson, S Chen, J Sun, B Knox, Y Jin, W Xiao, ... Archives of toxicology 92, 845-858, 2018 | 54 | 2018 |
A network pharmacology approach to evaluating the efficacy of Chinese medicine using genome-wide transcriptional expression data L Wu, Y Wang, J Nie, X Fan, Y Cheng Evidence-Based Complementary and Alternative Medicine 2013, 2013 | 53 | 2013 |
Identification of the effective constituents for anti-inflammatory activity of Ju-Zhi-Jiang-Tang, an ancient traditional Chinese medicine formula S Wang, P Chen, W Jiang, L Wu, L Chen, X Fan, Y Wang, Y Cheng Journal of Chromatography a 1348, 105-124, 2014 | 48 | 2014 |
Study of serious adverse drug reactions using FDA-approved drug labeling and MedDRA L Wu, T Ingle, Z Liu, A Zhao-Wong, S Harris, S Thakkar, G Zhou, J Yang, ... BMC bioinformatics 20, 129-139, 2019 | 42 | 2019 |
Fabry’s disease and stroke: Effectiveness of enzyme replacement therapy (ERT) in stroke prevention, a review with meta-analysis S Sheng, L Wu, K Nalleballe, R Sharma, A Brown, S Ranabothu, ... Journal of Clinical Neuroscience 65, 83-86, 2019 | 41 | 2019 |
Relating anatomical therapeutic indications by the ensemble similarity of drug sets L Wu, N Ai, Y Liu, Y Wang, X Fan Journal of chemical information and modeling 53 (8), 2154-2160, 2013 | 40 | 2013 |
A deep learning model to recognize food contaminating beetle species based on elytra fragments L Wu, Z Liu, T Bera, H Ding, DA Langley, A Jenkins-Barnes, C Furlanello, ... Computers and Electronics in Agriculture 166, 105002, 2019 | 39 | 2019 |
Trade-off predictivity and explainability for machine-learning powered predictive toxicology: An in-depth investigation with Tox21 data sets L Wu, R Huang, IV Tetko, Z Xia, J Xu, W Tong Chemical research in toxicology 34 (2), 541-549, 2021 | 38 | 2021 |
Toxicogenomic analysis of the particle dose-and size-response relationship of silica particles-induced toxicity in mice X Lu, T Jin, Y Jin, L Wu, B Hu, Y Tian, X Fan Nanotechnology 24 (1), 015106, 2012 | 31 | 2012 |
A verified genomic reference sample for assessing performance of cancer panels detecting small variants of low allele frequency W Jones, B Gong, N Novoradovskaya, D Li, R Kusko, TA Richmond, ... Genome biology 22, 1-38, 2021 | 30 | 2021 |
Network pharmacology study on major active compounds of Fufang Danshen formula X Li, L Wu, X Fan, B Zhang, X Gao, Y Wang, Y Cheng Zhongguo Zhong yao za zhi= Zhongguo Zhongyao Zazhi= China Journal of Chinese …, 2011 | 29 | 2011 |
Integrating drug’s mode of action into quantitative structure–activity relationships for improved prediction of drug-induced liver injury L Wu, Z Liu, S Auerbach, R Huang, M Chen, K McEuen, J Xu, H Fang, ... Journal of chemical information and modeling 57 (4), 1000-1006, 2017 | 26 | 2017 |
NGS evaluation of colorectal cancer reveals interferon gamma dependent expression of immune checkpoint genes and identification of novel IFNγ induced genes L Xu, L Pelosof, R Wang, HI McFarland, WW Wu, JN Phue, CT Lee, ... Frontiers in immunology 11, 224, 2020 | 24 | 2020 |