Leihong Wu (吴磊宏)
Leihong Wu (吴磊宏)
Division of Bioinformatics and Biostatistics, National Center of Toxicological Research, FDA
Verified email at fda.hhs.gov
Cited by
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A network pharmacology study of Chinese medicine QiShenYiQi to reveal its underlying multi-compound, multi-target, multi-pathway mode of action
X Li, L Wu, W Liu, Y Jin, Q Chen, L Wang, X Fan, Z Li, Y Cheng
PloS one 9 (5), e95004, 2014
Comparing SVM and ANN based machine learning methods for species identification of food contaminating beetles
H Bisgin, T Bera, H Ding, HG Semey, L Wu, Z Liu, AE Barnes, DA Langley, ...
Scientific reports 8 (1), 1-12, 2018
Identifying roles of “Jun-Chen-Zuo-Shi” component herbs of QiShenYiQi formula in treating acute myocardial ischemia by network pharmacology
L Wu, Y Wang, Z Li, B Zhang, Y Cheng, X Fan
Chinese medicine 9 (1), 1-9, 2014
Identification of the effective constituents for anti-inflammatory activity of Ju-Zhi-Jiang-Tang, an ancient traditional Chinese medicine formula
S Wang, P Chen, W Jiang, L Wu, L Chen, X Fan, Y Wang, Y Cheng
Journal of Chromatography a 1348, 105-124, 2014
Multiple microRNAs function as self-protective modules in acetaminophen-induced hepatotoxicity in humans
D Yu, L Wu, P Gill, WH Tolleson, S Chen, J Sun, B Knox, Y Jin, W Xiao, ...
Archives of toxicology 92 (2), 845-858, 2018
Comprehensive assessments of RNA-seq by the SEQC consortium: FDA-led efforts advance precision medicine
J Xu, B Gong, L Wu, S Thakkar, H Hong, W Tong
Pharmaceutics 8 (1), 8, 2016
A network pharmacology approach to evaluating the efficacy of Chinese medicine using genome-wide transcriptional expression data
L Wu, Y Wang, J Nie, X Fan, Y Cheng
Evidence-Based Complementary and Alternative Medicine 2013, 2013
Relating anatomical therapeutic indications by the ensemble similarity of drug sets
L Wu, N Ai, Y Liu, Y Wang, X Fan
Journal of chemical information and modeling 53 (8), 2154-2160, 2013
Network pharmacology study on major active compounds of Fufang Danshen formula
X Li, L Wu, X Fan, B Zhang, X Gao, Y Wang, Y Cheng
Zhongguo Zhong yao za zhi= Zhongguo zhongyao zazhi= China journal of Chinese …, 2011
Toxicogenomic analysis of the particle dose-and size-response relationship of silica particles-induced toxicity in mice
X Lu, T Jin, Y Jin, L Wu, B Hu, Y Tian, X Fan
Nanotechnology 24 (1), 015106, 2012
Consensus ranking approach to understanding the underlying mechanism with QSAR
L Shao, L Wu, X Fan, Y Cheng
Journal of chemical information and modeling 50 (11), 1941-1948, 2010
Drug-induced liver injury severity and toxicity (DILIst): binary classification of 1279 drugs by human hepatotoxicity
S Thakkar, T Li, Z Liu, L Wu, R Roberts, W Tong
Drug discovery today 25 (1), 201-208, 2020
LTMap: a web server for assessing the potential liver toxicity by genome‐wide transcriptional expression data
L Xing, L Wu, Y Liu, N Ai, X Lu, X Fan
Journal of Applied Toxicology 34 (7), 805-809, 2014
Determination of minimum training sample size for microarray-based cancer outcome prediction–an empirical assessment
L Shao, X Fan, N Cheng, L Wu, Y Cheng
PloS one 8 (7), e68579, 2013
T2D@ ZJU: a knowledgebase integrating heterogeneous connections associated with type 2 diabetes mellitus
Z Yang, J Yang, W Liu, L Wu, L Xing, Y Wang, X Fan, Y Cheng
Database 2013, 2013
Study of serious adverse drug reactions using FDA-approved drug labeling and MedDRA
L Wu, T Ingle, Z Liu, A Zhao-Wong, S Harris, S Thakkar, G Zhou, J Yang, ...
BMC bioinformatics 20 (2), 129-139, 2019
Direct comparison of performance of single nucleotide variant calling in human genome with alignment-based and assembly-based approaches
L Wu, G Yavas, H Hong, W Tong, W Xiao
Scientific reports 7 (1), 1-9, 2017
Integrating Drug’s Mode of Action into Quantitative Structure–Activity Relationships for Improved Prediction of Drug-Induced Liver Injury
L Wu, Z Liu, S Auerbach, R Huang, M Chen, K McEuen, J Xu, H Fang, ...
Journal of chemical information and modeling 57 (4), 1000-1006, 2017
Evaluating the analytical validity of circulating tumor DNA sequencing assays for precision oncology
IW Deveson, B Gong, K Lai, JS LoCoco, TA Richmond, J Schageman, ...
Nature biotechnology, 1-14, 2021
Challenges, solutions, and quality metrics of personal genome assembly in advancing precision medicine
W Xiao, L Wu, G Yavas, V Simonyan, B Ning, H Hong
Pharmaceutics 8 (2), 15, 2016
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