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Young Chan Chae
Young Chan Chae
Verified email at unist.ac.kr
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Year
Targeting mitochondrial biogenesis to overcome drug resistance to MAPK inhibitors
G Zhang, DT Frederick, L Wu, Z Wei, C Krepler, S Srinivasan, YC Chae, ...
The Journal of clinical investigation 126 (5), 1834-1856, 2016
2562016
Metabolic stress regulates cytoskeletal dynamics and metastasis of cancer cells
MC Caino, YC Chae, V Vaira, S Ferrero, M Nosotti, NM Martin, ...
The Journal of clinical investigation 123 (7), 2907-2920, 2013
2072013
PI3K therapy reprograms mitochondrial trafficking to fuel tumor cell invasion
MC Caino, JC Ghosh, YC Chae, V Vaira, DB Rivadeneira, A Faversani, ...
Proceedings of the National Academy of Sciences 112 (28), 8638-8643, 2015
2052015
Mitochondrial Akt regulation of hypoxic tumor reprogramming
YC Chae, V Vaira, MC Caino, HY Tang, JH Seo, AV Kossenkov, ...
Cancer cell 30 (2), 257-272, 2016
1982016
Landscape of the mitochondrial Hsp90 metabolome in tumours
YC Chae, A Angelin, S Lisanti, AV Kossenkov, KD Speicher, H Wang, ...
Nature communications 4 (1), 2139, 2013
1732013
Cancer stem cell metabolism: target for cancer therapy
YC Chae, JH Kim
BMB reports 51 (7), 319, 2018
1552018
The mitochondrial unfoldase-peptidase complex ClpXP controls bioenergetics stress and metastasis
JH Seo, DB Rivadeneira, MC Caino, YC Chae, DW Speicher, HY Tang, ...
PLoS biology 14 (7), e1002507, 2016
1392016
Control of tumor bioenergetics and survival stress signaling by mitochondrial HSP90s
YC Chae, MC Caino, S Lisanti, JC Ghosh, T Dohi, NN Danial, ...
Cancer cell 22 (3), 331-344, 2012
1342012
Adaptive mitochondrial reprogramming and resistance to PI3K therapy
JC Ghosh, MD Siegelin, V Vaira, A Faversani, M Tavecchio, YC Chae, ...
Journal of the National Cancer Institute 107 (3), dju502, 2015
1142015
Phospholipase D activity regulates integrin-mediated cell spreading and migration by inducing GTP-Rac translocation to the plasma membrane
YC Chae, JH Kim, KL Kim, HW Kim, HY Lee, WD Heo, T Meyer, PG Suh, ...
Molecular biology of the cell 19 (7), 3111-3123, 2008
1102008
ITGB4-mediated metabolic reprogramming of cancer-associated fibroblasts
JS Sung, CW Kang, S Kang, Y Jang, YC Chae, BG Kim, NH Cho
Oncogene 39 (3), 664-676, 2020
1052020
Interplay between TRAP1 and sirtuin-3 modulates mitochondrial respiration and oxidative stress to maintain stemness of glioma stem cells
HK Park, JH Hong, YT Oh, SS Kim, J Yin, AJ Lee, YC Chae, JH Kim, ...
Cancer research 79 (7), 1369-1382, 2019
902019
Unleashing the full potential of Hsp90 inhibitors as cancer therapeutics through simultaneous inactivation of Hsp90, Grp94, and TRAP1
HK Park, NG Yoon, JE Lee, S Hu, S Yoon, SY Kim, JH Hong, D Nam, ...
Experimental & molecular medicine 52 (1), 79-91, 2020
882020
Mitochondrial HSP90 accumulation promotes vascular remodeling in pulmonary arterial hypertension
O Boucherat, T Peterlini, A Bourgeois, V Nadeau, S Breuils-Bonnet, ...
American journal of respiratory and critical care medicine 198 (1), 90-103, 2018
862018
Collapsin response mediator protein-2 regulates neurite formation by modulating tubulin GTPase activity
YC Chae, S Lee, K Heo, SH Ha, Y Jung, JH Kim, Y Ihara, PG Suh, SH Ryu
Cellular signalling 21 (12), 1818-1826, 2009
712009
Deletion of the mitochondrial chaperone TRAP-1 uncovers global reprogramming of metabolic networks
S Lisanti, M Tavecchio, YC Chae, Q Liu, AK Brice, ML Thakur, ...
Cell Reports 8 (3), 671-677, 2014
682014
PLCγ1: potential arbitrator of cancer progression
HJ Jang, PG Suh, YJ Lee, KJ Shin, L Cocco, YC Chae
Advances in biological regulation 67, 179-189, 2018
602018
RGS2 promotes formation of neurites by stimulating microtubule polymerization
K Heo, SH Ha, YC Chae, S Lee, YS Oh, YH Kim, SH Kim, JH Kim, ...
Cellular signalling 18 (12), 2182-2192, 2006
592006
Inhibition of muscarinic receptor-linked phospholipase D activation by association with tubulin
YC Chae, S Lee, HY Lee, K Heo, JH Kim, JH Kim, PG Suh, SH Ryu
Journal of Biological Chemistry 280 (5), 3723-3730, 2005
542005
Epidermal growth factor increases insulin secretion and lowers blood glucose in diabetic mice
HY Lee, K Yea, J Kim, BD Lee, YC Chae, HS Kim, DW Lee, SH Kim, ...
Journal of cellular and molecular medicine 12 (5a), 1593-1604, 2008
532008
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Articles 1–20