Mark Febbraio
Mark Febbraio
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Muscles, exercise and obesity: skeletal muscle as a secretory organ
BK Pedersen, MA Febbraio
Nature Reviews Endocrinology 8 (8), 457-465, 2012
Muscle as an endocrine organ: focus on muscle-derived interleukin-6
BK Pedersen, MA Febbraio
Physiological reviews 88 (4), 1379-1406, 2008
Muscle‐derived interleukin‐6: mechanisms for activation and possible biological roles
MA Febbraio, BK Pedersen
The FASEB journal 16 (11), 1335-1347, 2002
Exercise and IL‐6 infusion inhibit endotoxin‐induced TNF‐α production in humans
R Starkie, SR Ostrowski, S Jauffred, M Febbraio, BK Pedersen
The FASEB Journal 17 (8), 1-10, 2003
Interleukin-6 increases insulin-stimulated glucose disposal in humans and glucose uptake and fatty acid oxidation in vitro via AMP-activated protein kinase
AL Carey, GR Steinberg, SL Macaulay, WG Thomas, AG Holmes, ...
Diabetes 55 (10), 2688-2697, 2006
Interleukin-6 stimulates lipolysis and fat oxidation in humans
G Van Hall, A Steensberg, M Sacchetti, C Fischer, C Keller, P Schjerling, ...
The Journal of Clinical Endocrinology & Metabolism 88 (7), 3005-3010, 2003
Exosome-dependent trafficking of HSP70: a novel secretory pathway for cellular stress proteins
GI Lancaster, MA Febbraio
Journal of Biological Chemistry 280 (24), 23349-23355, 2005
Searching for the exercise factor: is IL-6 a candidate?
BK Pedersen, A Steensberg, C Fischer, C Keller, P Keller, P Plomgaard, ...
Journal of Muscle Research & Cell Motility 24 (2), 113-119, 2003
Signaling by IL-6 promotes alternative activation of macrophages to limit endotoxemia and obesity-associated resistance to insulin
J Mauer, B Chaurasia, J Goldau, MC Vogt, J Ruud, KD Nguyen, ...
Nature immunology 15 (5), 423-430, 2014
Brain-derived neurotrophic factor is produced by skeletal muscle cells in response to contraction and enhances fat oxidation via activation of AMP-activated protein kinase
VB Matthews, MB Åström, MHS Chan, CR Bruce, KS Krabbe, O Prelovsek, ...
Diabetologia 52 (7), 1409-1418, 2009
Reactive oxygen species enhance insulin sensitivity
K Loh, H Deng, A Fukushima, X Cai, B Boivin, S Galic, C Bruce, ...
Cell metabolism 10 (4), 260-272, 2009
Macrophage PPARγ is required for normal skeletal muscle and hepatic insulin sensitivity and full antidiabetic effects of thiazolidinediones
AL Hevener, JM Olefsky, D Reichart, MTA Nguyen, G Bandyopadyhay, ...
The Journal of clinical investigation 117 (6), 1658-1669, 2007
HSP72 protects against obesity-induced insulin resistance
J Chung, AK Nguyen, DC Henstridge, AG Holmes, MHS Chan, JL Mesa, ...
Proceedings of the National Academy of Sciences 105 (5), 1739-1744, 2008
IL-6 and TNF-α expression in, and release from, contracting human skeletal muscle
A Steensberg, C Keller, RL Starkie, T Osada, MA Febbraio, BK Pedersen
American Journal of Physiology-Endocrinology and Metabolism 283 (6), E1272-E1278, 2002
Contraction-induced myokine production and release: is skeletal muscle an endocrine organ?
MA Febbraio, BK Pedersen
Exercise and sport sciences reviews 33 (3), 114-119, 2005
Interleukin‐6 production in contracting human skeletal muscle is influenced by pre‐exercise muscle glycogen content
A Steensberg, MA Febbraio, T Osada, P Schjerling, G Van Hall, B Saltin, ...
The Journal of physiology 537 (2), 633-639, 2001
Tumor necrosis factor α-induced skeletal muscle insulin resistance involves suppression of AMP-kinase signaling
GR Steinberg, BJ Michell, BJW van Denderen, MJ Watt, AL Carey, ...
Cell metabolism 4 (6), 465-474, 2006
Interleukin-6 is a novel factor mediating glucose homeostasis during skeletal muscle contraction
MA Febbraio, N Hiscock, M Sacchetti, CP Fischer, BK Pedersen
Diabetes 53 (7), 1643-1648, 2004
Intramuscular heat shock protein 72 and heme oxygenase-1 mRNA are reduced in patients with type 2 diabetes: evidence that insulin resistance is associated with a disturbed …
CR Bruce, AL Carey, JA Hawley, MA Febbraio
Diabetes 52 (9), 2338-2345, 2003
High-density lipoprotein modulates glucose metabolism in patients with type 2 diabetes mellitus
BG Drew, SJ Duffy, MF Formosa, AK Natoli, DC Henstridge, SA Penfold, ...
Circulation 119 (15), 2103, 2009
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