| A Comprehensive Human Gastric Cancer Organoid Biobank Captures Tumor Subtype Heterogeneity and Enables Therapeutic Screening LSY Yan HHN, Siu HC, Law S, Ho SL, Yue SSK, Tsui WY, Chan D, Chan AS, Ma S ... Cell Stem Cell 23 (6), 882-897, 2018 | 522 | 2018 |
| Evidence that mitotic exit is a better cancer therapeutic target than spindle assembly HC Huang, J Shi, JD Orth, TJ Mitchison Cancer cell 16 (4), 347-358, 2009 | 321 | 2009 |
| Lysyl oxidase‐like 2 is critical to tumor microenvironment and metastatic niche formation in hepatocellular carcinoma CCL Wong, APW Tse, YP Huang, YT Zhu, DKC Chiu, RKH Lai, SLK Au, ... Hepatology 60 (5), 1645-1658, 2014 | 270 | 2014 |
| Cell type variation in responses to antimitotic drugs that target microtubules and kinesin-5 J Shi, JD Orth, T Mitchison Cancer research 68 (9), 3269-3276, 2008 | 262 | 2008 |
| Attractor landscape analysis reveals feedback loops in the p53 network that control the cellular response to DNA damage M Choi, J Shi, SH Jung, X Chen, KH Cho Science signaling 5 (251), ra83-ra83, 2012 | 184 | 2012 |
| Quantitative live imaging of cancer and normal cells treated with Kinesin-5 inhibitors indicates significant differences in phenotypic responses and cell fate MTJ Orth JD, Tang Y, Shi J, Loy CT, Amendt C, Wilm C, Zenke FT Molecular Cancer Therapeutics 7 (11), 3480-3489, 2008 | 134 | 2008 |
| Navitoclax (ABT-263) accelerates apoptosis during drug-induced mitotic arrest by antagonizing Bcl-xL J Shi, Y Zhou, HC Huang, TJ Mitchison Cancer research 71 (13), 4518-4526, 2011 | 130 | 2011 |
| DNA damage strength modulates a bimodal switch of p53 dynamics for cell-fate control X Chen, J Chen, S Gan, H Guan, Y Zhou, Q Ouyang, J Shi BMC biology 11, 1-11, 2013 | 125 | 2013 |
| MiR-200b/200c/429 subfamily negatively regulates Rho/ROCK signaling pathway to suppress hepatocellular carcinoma metastasis CM Wong, L Wei, SLK Au, DNY Fan, Y Zhou, FHC Tsang, CT Law, ... Oncotarget 6 (15), 13658, 2015 | 94 | 2015 |
| Fas ligand and lytic granule differentially control cytotoxic dynamics of Natural Killer cell against cancer target. Y Zhu, B Huang, J Shi Oncotarget 7 (30), 47163-47172, 2016 | 84 | 2016 |
| Cell death response to anti-mitotic drug treatment in cell culture, mouse tumor model and the clinic J Shi, TJ Mitchison endocrine-related cancer 24 (9), T83-T96, 2017 | 82 | 2017 |
| Is inflammatory micronucleation the key to a successful anti-mitotic cancer drug? TJ Mitchison, J Pineda, J Shi, S Florian Open Biology 7 (11), pii: 170182, 2017 | 72 | 2017 |
| Stochastic competition between mechanistically independent slippage and death pathways determines cell fate during mitotic arrest HC Huang, TJ Mitchison, J Shi PloS one 5 (12), e15724, 2010 | 69 | 2010 |
| Post-slippage multinucleation renders cytotoxic variation in anti-mitotic drugs that target the microtubules or mitotic spindle Y Zhu, Y Zhou, J Shi Cell cycle 13 (11), 1756-1764, 2014 | 65 | 2014 |
| Comparative in vitro cytotoxicity study on uncoated magnetic nanoparticles: effects on cell viability, cell morphology, and cellular uptake L Li, KY Mak, J Shi, HK Koon, CH Leung, CM Wong, CW Leung, CSK Mak, ... Journal of nanoscience and nanotechnology 12 (12), 9010-9017, 2012 | 57 | 2012 |
| Single-molecule kinetics reveals signatures of half-sites reactivity in dihydroorotate dehydrogenase A catalysis J Shi, J Dertouzos, A Gafni, D Steel, BA Palfey Proceedings of the National Academy of Sciences 103 (15), 5775-5780, 2006 | 56 | 2006 |
| Multiple states of the Tyr318Leu mutant of dihydroorotate dehydrogenase revealed by single-molecule kinetics J Shi, BA Palfey, J Dertouzos, KF Jensen, A Gafni, D Steel Journal of the American Chemical Society 126 (22), 6914-6922, 2004 | 55 | 2004 |
| Network dynamics-based stratification of cancer panel for systemic prediction of anticancer drug response. M Choi, J Shi, Y Zhu, R Yang, KH Cho Nature Communications 8 (1), 1940, 2017 | 41* | 2017 |
| Liver cancer immunoassay with magnetic nanoparticles and MgO-based magnetic tunnel junction sensors ZQ Lei, L Li, GJ Li, CW Leung, J Shi, CM Wong, KC Lo, WK Chan, ... Journal of applied physics 111 (7), 2012 | 41 | 2012 |
| Sterilization on dextran-coated iron oxide nanoparticles: Effects of autoclaving, filtration, UV irradiation, and ethanol treatment L Li, KY Mak, J Shi, CH Leung, CM Wong, CW Leung, CSK Mak, KY Chan, ... Microelectronic engineering 111, 310-313, 2013 | 40 | 2013 |
