Srinivas Viswanathan
Srinivas Viswanathan
Dana-Farber Cancer Institute / Broad Institute
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Selective blockade of microRNA processing by Lin28
SR Viswanathan, GQ Daley, RI Gregory
Science 320 (5872), 97-100, 2008
Lin28 promotes transformation and is associated with advanced human malignancies
SR Viswanathan, JT Powers, W Einhorn, Y Hoshida, TL Ng, S Toffanin, ...
Nature genetics 41 (7), 843-848, 2009
Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway
VS Viswanathan, MJ Ryan, HD Dhruv, S Gill, OM Eichhoff, ...
Nature 547 (7664), 453-457, 2017
Lin28: A microRNA regulator with a macro role
SR Viswanathan, GQ Daley
Cell 140 (4), 445-449, 2010
A role for Lin28 in primordial germ-cell development and germ-cell malignancy
JA West, SR Viswanathan, A Yabuuchi, K Cunniff, A Takeuchi, IH Park, ...
Nature 460 (7257), 909-913, 2009
Determinants of microRNA processing inhibition by the developmentally regulated RNA-binding protein Lin28
E Piskounova, SR Viswanathan, M Janas, RJ LaPierre, GQ Daley, P Sliz, ...
Journal of Biological Chemistry 283 (31), 21310-21314, 2008
Lin28a transgenic mice manifest size and puberty phenotypes identified in human genetic association studies
H Zhu, S Shah, N Shyh-Chang, G Shinoda, WS Einhorn, SR Viswanathan, ...
Nature genetics 42 (7), 626-630, 2010
Derivation and external validation of the PLASMIC score for rapid assessment of adults with thrombotic microangiopathies: a cohort study
PK Bendapudi, S Hurwitz, A Fry, MB Marques, SW Waldo, A Li, L Sun, ...
The Lancet Haematology 4 (4), e157-e164, 2017
Structural alterations driving castration-resistant prostate cancer revealed by linked-read genome sequencing
SR Viswanathan, G Ha, AM Hoff, JA Wala, J Carrot-Zhang, CW Whelan, ...
Cell 174 (2), 433-447. e19, 2018
Ras-MAPK signaling promotes trophectoderm formation from embryonic stem cells and mouse embryos
CW Lu, A Yabuuchi, L Chen, S Viswanathan, K Kim, GQ Daley
Nature genetics 40 (7), 921-926, 2008
LIN28 cooperates with WNT signaling to drive invasive intestinal and colorectal adenocarcinoma in mice and humans
HC Tu, S Schwitalla, Z Qian, GS LaPier, A Yermalovich, YC Ku, SC Chen, ...
Genes & development 29 (10), 1074-1086, 2015
microRNA expression during trophectoderm specification
SR Viswanathan, CH Mermel, J Lu, CW Lu, TR Golub, GQ Daley
PloS one 4 (7), e6143, 2009
Prostate cancer reactivates developmental epigenomic programs during metastatic progression
MM Pomerantz, X Qiu, Y Zhu, DY Takeda, W Pan, SC Baca, A Gusev, ...
Nature Genetics 52 (8), 790-799, 2020
N-linked glycosylation is required for optimal function of Kaposi's sarcoma herpesvirus–encoded, but not cellular, interleukin 6
CS Dela Cruz, Y Lee, SR Viswanathan, AS El-Guindy, J Gerlach, ...
The Journal of experimental medicine 199 (4), 503-514, 2004
Genome-scale analysis identifies paralog lethality as a vulnerability of chromosome 1p loss in cancer
SR Viswanathan, MF Nogueira, CG Buss, JM Krill-Burger, MJ Wawer, ...
Nature genetics 50 (7), 937-943, 2018
Methods to regulate MIRNA Processing by targeting LIN-28
RI Gregory, GQ Daley, SR Viswanathan
US Patent 8,283,331, 2012
Integrative molecular characterization of sarcomatoid and rhabdoid renal cell carcinoma
Z Bakouny, DA Braun, SA Shukla, W Pan, X Gao, Y Hou, A Flaifel, S Tang, ...
Nature communications 12 (1), 1-14, 2021
Complex N-linked glycans on Asn-89 of Kaposi sarcoma herpes virus-encoded interleukin-6 mediate optimal function by affecting cytokine protein conformation
CSD Cruz, SR Viswanathan, AS El-Guindy, D Shedd, G Miller
Journal of Biological Chemistry 284 (43), 29269-29282, 2009
Gallbladder lymphoma
SR Viswanathan, Z Khalpey, SW Ashley
Medical Oncology 28 (3), 810-812, 2011
Efficacy of cabozantinib in advanced MiT family translocation renal cell carcinomas (TRCC).
J Thouvenin, O Alhalabi, L Hirsch, E Hasanov, P Barthelemy, DJ Martini, ...
Journal of Clinical Oncology 39 (6_suppl), 274-274, 2021
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