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Jonathan P. Godbout. PhD
Jonathan P. Godbout. PhD
Professor of Neuroscience,The Ohio State University
Geverifieerd e-mailadres voor osumc.edu - Homepage
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Neuroinflammation: the devil is in the details
DJ DiSabato, N Quan, JP Godbout
Journal of neurochemistry 139, 136-153, 2016
13302016
Exaggerated neuroinflammation and sickness behavior in aged mice after activation of the peripheral innate immune system
JP Godbout, J Chen, J Abraham, AF Richwine, BM Berg, KW Kelley, ...
The FASEB journal 19 (10), 1329-1331, 2005
9972005
Microglia of the aged brain: primed to be activated and resistant to regulation
DM Norden, JP Godbout
Neuropathology and applied neurobiology 39 (1), 19-34, 2013
8082013
β-Adrenergic receptor antagonism prevents anxiety-like behavior and microglial reactivity induced by repeated social defeat
ES Wohleb, ML Hanke, AW Corona, ND Powell, MS La'Tonia, MT Bailey, ...
Journal of Neuroscience 31 (17), 6277-6288, 2011
7272011
Minocycline attenuates lipopolysaccharide (LPS)-induced neuroinflammation, sickness behavior, and anhedonia
CJ Henry, Y Huang, A Wynne, M Hanke, J Himler, MT Bailey, JF Sheridan, ...
Journal of neuroinflammation 5, 1-14, 2008
7252008
Peripheral lipopolysaccharide (LPS) challenge promotes microglial hyperactivity in aged mice that is associated with exaggerated induction of both pro-inflammatory IL-1β and …
CJ Henry, Y Huang, AM Wynne, JP Godbout
Brain, behavior, and immunity 23 (3), 309-317, 2009
6582009
Microglia induce motor neuron death via the classical NF-κB pathway in amyotrophic lateral sclerosis
AE Frakes, L Ferraiuolo, AM Haidet-Phillips, L Schmelzer, L Braun, ...
Neuron 81 (5), 1009-1023, 2014
6502014
Stress-induced recruitment of bone marrow-derived monocytes to the brain promotes anxiety-like behavior
ES Wohleb, ND Powell, JP Godbout, JF Sheridan
Journal of Neuroscience 33 (34), 13820-13833, 2013
6002013
Stress-induced immune dysregulation: implications for wound healing, infectious disease and cancer
JP Godbout, R Glaser
Journal of Neuroimmune Pharmacology 1, 421-427, 2006
5842006
Sequential activation of microglia and astrocyte cytokine expression precedes increased Iba‐1 or GFAP immunoreactivity following systemic immune challenge
DM Norden, PJ Trojanowski, E Villanueva, E Navarro, JP Godbout
Glia 64 (2), 300-316, 2016
5432016
Neuroinflammation and disruption in working memory in aged mice after acute stimulation of the peripheral innate immune system
J Chen, JB Buchanan, NL Sparkman, JP Godbout, GG Freund, ...
Brain, behavior, and immunity 22 (3), 301-311, 2008
4822008
Monocyte trafficking to the brain with stress and inflammation: a novel axis of immune-to-brain communication that influences mood and behavior
ES Wohleb, DB McKim, JF Sheridan, JP Godbout
Frontiers in neuroscience 8, 447, 2015
4512015
Microglial priming and enhanced reactivity to secondary insult in aging, and traumatic CNS injury, and neurodegenerative disease
DM Norden, MM Muccigrosso, JP Godbout
Neuropharmacology 96, 29-41, 2015
3942015
Microglia priming with aging and stress
A Niraula, JF Sheridan, JP Godbout
Neuropsychopharmacology 42 (1), 318-333, 2017
3502017
Aging exacerbates depressive-like behavior in mice in response to activation of the peripheral innate immune system
JP Godbout, M Moreau, J Lestage, J Chen, NL Sparkman, JO Connor, ...
Neuropsychopharmacology 33 (10), 2341-2351, 2008
3472008
Microglial recruitment of IL-1β-producing monocytes to brain endothelium causes stress-induced anxiety
DB McKim, MD Weber, A Niraula, CM Sawicki, X Liu, BL Jarrett, ...
Molecular psychiatry 23 (6), 1421-1431, 2018
3332018
Peripheral innate immune challenge exaggerated microglia activation, increased the number of inflammatory CNS macrophages, and prolonged social withdrawal in socially defeated mice
ES Wohleb, AM Fenn, AM Pacenta, ND Powell, JF Sheridan, JP Godbout
Psychoneuroendocrinology 37 (9), 1491-1505, 2012
3182012
Re-establishment of anxiety in stress-sensitized mice is caused by monocyte trafficking from the spleen to the brain
ES Wohleb, DB McKim, DT Shea, ND Powell, AJ Tarr, JF Sheridan, ...
Biological psychiatry 75 (12), 970-981, 2014
3132014
TGFβ produced by IL‐10 redirected astrocytes attenuates microglial activation
DM Norden, AM Fenn, A Dugan, JP Godbout
Glia 62 (6), 881-895, 2014
3022014
Immune activation promotes depression 1 month after diffuse brain injury: a role for primed microglia
AM Fenn, JC Gensel, Y Huang, PG Popovich, J Lifshitz, JP Godbout
Biological psychiatry 76 (7), 575-584, 2014
2882014
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Artikelen 1–20