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Michael Tolstorukov
Michael Tolstorukov
Dana-Farber Cancer Institute
Geverifieerd e-mailadres voor mail.dfci.harvard.edu - Homepage
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ChIP-seq guidelines and practices of the ENCODE and modENCODE consortia
SG Landt, GK Marinov, A Kundaje, P Kheradpour, F Pauli, S Batzoglou, ...
Genome research 22 (9), 1813-1831, 2012
21952012
Identification of Functional Elements and Regulatory Circuits by Drosophila modENCODE
modENCODE Consortium, S Roy, J Ernst, PV Kharchenko, P Kheradpour, ...
Science 330 (6012), 1787-1797, 2010
10712010
Design and analysis of ChIP-seq experiments for DNA-binding proteins
PV Kharchenko, MY Tolstorukov, PJ Park
Nature biotechnology 26 (12), 1351-1359, 2008
10662008
Comprehensive analysis of the chromatin landscape in Drosophila melanogaster
PV Kharchenko, AA Alekseyenko, YB Schwartz, A Minoda, NC Riddle, ...
Nature 471 (7339), 480-485, 2011
9752011
The long noncoding RNAs NEAT1 and MALAT1 bind active chromatin sites
JA West, CP Davis, H Sunwoo, MD Simon, RI Sadreyev, PI Wang, ...
Molecular cell 55 (5), 791-802, 2014
6412014
Comparative analysis of metazoan chromatin organization
JWK Ho, YL Jung, T Liu, BH Alver, S Lee, K Ikegami, KA Sohn, A Minoda, ...
Nature 512 (7515), 449-452, 2014
4122014
CpG islands recruit a histone H3 lysine 36 demethylase
NP Blackledge, JC Zhou, MY Tolstorukov, AM Farcas, PJ Park, RJ Klose
Molecular cell 38 (2), 179-190, 2010
3592010
Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate
AA Chakraborty, T Laukka, M Myllykoski, AE Ringel, MA Booker, ...
Science 363 (6432), 1217-1222, 2019
3412019
SMARCB1-mediated SWI/SNF complex function is essential for enhancer regulation
X Wang, RS Lee, BH Alver, JR Haswell, S Wang, J Mieczkowski, Y Drier, ...
Nature genetics 49 (2), 289-295, 2017
3112017
Plasticity in patterns of histone modifications and chromosomal proteins in Drosophila heterochromatin
NC Riddle, A Minoda, PV Kharchenko, AA Alekseyenko, YB Schwartz, ...
Genome Research 21 (2), 147-163, 2011
2762011
Loss of the tumor suppressor Snf5 leads to aberrant activation of the Hedgehog-Gli pathway
Z Jagani, EL Mora-Blanco, CG Sansam, ES McKenna, B Wilson, D Chen, ...
Nature medicine 16 (12), 1429-1433, 2010
2572010
Microenvironment drives cell state, plasticity, and drug response in pancreatic cancer
S Raghavan, PS Winter, AW Navia, HL Williams, A DenAdel, KE Lowder, ...
Cell 184 (25), 6119-6137. e26, 2021
2412021
A novel roll-and-slide mechanism of DNA folding in chromatin: implications for nucleosome positioning
MY Tolstorukov, AV Colasanti, DM McCandlish, WK Olson, VB Zhurkin
Journal of molecular biology 371 (3), 725-738, 2007
2402007
MNase titration reveals differences between nucleosome occupancy and chromatin accessibility
J Mieczkowski, A Cook, SK Bowman, B Mueller, BH Alver, S Kundu, ...
Nature communications 7 (1), 11485, 2016
2372016
Swi/Snf chromatin remodeling/tumor suppressor complex establishes nucleosome occupancy at target promoters
MY Tolstorukov, CG Sansam, P Lu, EC Koellhoffer, KC Helming, BH Alver, ...
Proceedings of the National Academy of Sciences 110 (25), 10165-10170, 2013
2042013
Nature and function of insulator protein binding sites in the Drosophila genome
YB Schwartz, D Linder-Basso, PV Kharchenko, MY Tolstorukov, M Kim, ...
Genome research 22 (11), 2188-2198, 2012
2002012
Impact of sequencing depth in ChIP-seq experiments
YL Jung, LJ Luquette, JWK Ho, F Ferrari, M Tolstorukov, A Minoda, ...
Nucleic acids research 42 (9), e74-e74, 2014
1982014
Diminished efficacy of programmed death-(ligand) 1 inhibition in STK11-and KEAP1-mutant lung adenocarcinoma is affected by KRAS mutation status
B Ricciuti, KC Arbour, JJ Lin, A Vajdi, N Vokes, L Hong, J Zhang, ...
Journal of Thoracic Oncology 17 (3), 399-410, 2022
1842022
Histone variant H2A. Bbd is associated with active transcription and mRNA processing in human cells
MY Tolstorukov, JA Goldman, C Gilbert, V Ogryzko, RE Kingston, PJ Park
Molecular cell 47 (4), 596-607, 2012
1502012
Association of high tumor mutation burden in non–small cell lung cancers with increased immune infiltration and improved clinical outcomes of PD-L1 blockade across PD-L1 …
B Ricciuti, X Wang, JV Alessi, H Rizvi, NR Mahadevan, YY Li, A Polio, ...
JAMA oncology 8 (8), 1160-1168, 2022
1392022
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