| Pharmacological effects of Lu AA21004: a novel multimodal compound for the treatment of major depressive disorder A Mørk, A Pehrson, LT Brennum, SM Nielsen, H Zhong, AB Lassen, ... Journal of Pharmacology and Experimental Therapeutics 340 (3), 666-675, 2012 | 354 | 2012 |
| Brexpiprazole I: in vitro and in vivo characterization of a novel serotonin-dopamine activity modulator K Maeda, H Sugino, H Akazawa, N Amada, J Shimada, T Futamura, ... Journal of pharmacology and experimental therapeutics 350 (3), 589-604, 2014 | 334 | 2014 |
| Serotonergic modulation of glutamate neurotransmission as a strategy for treating depression and cognitive dysfunction AL Pehrson, C Sanchez CNS spectrums 19 (2), 121-133, 2014 | 189 | 2014 |
| Lu AA21004, a novel multimodal antidepressant, produces regionally selective increases of multiple neurotransmitters—a rat microdialysis and electrophysiology study AL Pehrson, T Cremers, C Bétry, MGC van der Hart, L Jørgensen, ... European Neuropsychopharmacology 23 (2), 133-145, 2013 | 179 | 2013 |
| Altered γ-aminobutyric acid neurotransmission in major depressive disorder: a critical review of the supporting evidence and the influence of serotonergic antidepressants AL Pehrson, C Sanchez Drug design, development and therapy, 603-624, 2015 | 168 | 2015 |
| Effects of serotonin in the hippocampus: how SSRIs and multimodal antidepressants might regulate pyramidal cell function E Dale, AL Pehrson, T Jeyarajah, Y Li, SC Leiser, G Smagin, CK Olsen, ... CNS spectrums 21 (2), 143-161, 2016 | 152 | 2016 |
| Treatment of cognitive dysfunction in major depressive disorder—a review of the preclinical evidence for efficacy of selective serotonin reuptake inhibitors, serotonin … AL Pehrson, SC Leiser, M Gulinello, E Dale, Y Li, JA Waller, C Sanchez European journal of pharmacology 753, 19-31, 2015 | 151 | 2015 |
| Antidepressant and anxiolytic potential of the multimodal antidepressant vortioxetine (Lu AA21004) assessed by behavioural and neurogenesis outcomes in mice JP Guilloux, I Mendez-David, A Pehrson, BP Guiard, C Repérant, ... Neuropharmacology 73, 147-159, 2013 | 148 | 2013 |
| Vortioxetine dose-dependently reverses 5-HT depletion-induced deficits in spatial working and object recognition memory: a potential role for 5-HT1A receptor agonism and 5-HT3 … KG du Jardin, JB Jensen, C Sanchez, AL Pehrson European Neuropsychopharmacology 24 (1), 160-171, 2014 | 139 | 2014 |
| Serotonergic regulation of prefrontal cortical circuitries involved in cognitive processing: a review of individual 5-HT receptor mechanisms and concerted effects of 5-HT … SC Leiser, Y Li, AL Pehrson, E Dale, G Smagin, C Sanchez ACS chemical neuroscience 6 (7), 970-986, 2015 | 115 | 2015 |
| Vortioxetine restores reversal learning impaired by 5-HT depletion or chronic intermittent cold stress in rats A Wallace, AL Pehrson, C Sánchez, DA Morilak International Journal of Neuropsychopharmacology 17 (10), 1695-1706, 2014 | 111 | 2014 |
| Vortioxetine, but not escitalopram or duloxetine, reverses memory impairment induced by central 5-HT depletion in rats: evidence for direct 5-HT receptor modulation JB Jensen, KG du Jardin, D Song, D Budac, G Smagin, C Sanchez, ... European Neuropsychopharmacology 24 (1), 148-159, 2014 | 102 | 2014 |
| Reversal of age-associated cognitive deficits is accompanied by increased plasticity-related gene expression after chronic antidepressant administration in middle-aged mice Y Li, A Abdourahman, JA Tamm, AL Pehrson, C Sánchez, M Gulinello Pharmacology Biochemistry and Behavior 135, 70-82, 2015 | 85 | 2015 |
| A rodent model of premenstrual dysphoria: progesterone withdrawal induces depression-like behavior that is differentially sensitive to classes of antidepressants Y Li, AL Pehrson, DP Budac, C Sánchez, M Gulinello Behavioural brain research 234 (2), 238-247, 2012 | 85 | 2012 |
| In vitro and in vivo effects of the multimodal antidepressant vortioxetine (Lu AA21004) at human and rat targets L Westrich, A Pehrson, H Zhong, SM Nielsen, K Frederiksen, TB Stensbøl, ... Int J Psychiatry Clin Pract 16 (Suppl 1), 47, 2012 | 85 | 2012 |
| A critical evaluation of the activity-regulated cytoskeleton-associated protein (Arc/Arg3. 1)'s putative role in regulating dendritic plasticity, cognitive processes, and mood … Y Li, AL Pehrson, JA Waller, E Dale, C Sanchez, M Gulinello Frontiers in neuroscience 9, 156021, 2015 | 83 | 2015 |
| The rapid recovery of 5-HT cell firing induced by the antidepressant vortioxetine involves 5-HT3 receptor antagonism C Bétry, AL Pehrson, A Etiévant, B Ebert, C Sánchez, N Haddjeri International Journal of Neuropsychopharmacology 16 (5), 1115-1127, 2013 | 72 | 2013 |
| Effect of the multimodal acting antidepressant vortioxetine on rat hippocampal plasticity and recognition memory C Bétry, A Etiévant, A Pehrson, C Sánchez, N Haddjeri Progress in Neuro-Psychopharmacology and Biological Psychiatry 58, 38-46, 2015 | 65 | 2015 |
| The influence of NMDA and GABAA receptors and glutamic acid decarboxylase (GAD) activity on attention AL Pehrson, CO Bondi, NKB Totah, B Moghaddam Psychopharmacology 225, 31-39, 2013 | 65 | 2013 |
| Multimodal antidepressant vortioxetine increases frontal cortical oscillations unlike escitalopram and duloxetine–a quantitative EEG study in rats SC Leiser, AL Pehrson, PJ Robichaud, C Sanchez British journal of pharmacology 171 (18), 4255-4272, 2014 | 60 | 2014 |
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