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Jonathan Kennedy
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Modulation of polyketide synthase activity by accessory proteins during lovastatin biosynthesis
J Kennedy, K Auclair, SG Kendrew, C Park, JC Vederas, CR Hutchinson
Science 284 (5418), 1368-1372, 1999
8501999
Lovastatin nonaketide synthase catalyzes an intramolecular Diels-Alder reaction of a substrate analogue
K Auclair, A Sutherland, J Kennedy, DJ Witter, JP Van den Heever, ...
Journal of the American Chemical Society 122 (46), 11519-11520, 2000
3462000
Marine metagenomics: strategies for the discovery of novel enzymes with biotechnological applications from marine environments
J Kennedy, JR Marchesi, ADW Dobson
Microb Cell Fact 7 (1), 27, 2008
2702008
Isolation and analysis of bacteria with antimicrobial activities from the marine sponge Haliclona simulans collected from Irish waters
J Kennedy, P Baker, C Piper, PD Cotter, M Walsh, MJ Mooij, MB Bourke, ...
Marine Biotechnology 11 (3), 384-396, 2009
2602009
Production of the antitumor drug epirubicin (4′-epidoxorubicin) and its precursor by a genetically engineered strain of Streptomyces peucetius
K Madduri, J Kennedy, G Rivola, A Inventi-Solari, S Filippini, G Zanuso, ...
Nature biotechnology 16 (1), 69-74, 1998
2181998
Targeted covalent inactivation of protein kinases by resorcylic acid lactone polyketides
A Schirmer, J Kennedy, S Murli, R Reid, DV Santi
Proceedings of the National Academy of Sciences of the United States of …, 2006
2072006
Marine metagenomics: new tools for the study and exploitation of marine microbial metabolism
J Kennedy, B Flemer, SA Jackson, DPH Lejon, JP Morrissey, F O’Gara, ...
Marine drugs 8 (3), 608-628, 2010
2032010
Heterologous production of epothilone C and D in Escherichia coli
SC Mutka, JR Carney, Y Liu, J Kennedy
Biochemistry 45 (4), 1321-1330, 2006
1852006
Mutasynthesis, chemobiosynthesis, and back to semi-synthesis: combining synthetic chemistry and biosynthetic engineering for diversifying natural products
J Kennedy
Natural product reports 25 (1), 25-34, 2008
1832008
Metabolic engineering of Escherichia coli for improved 6-deoxyerythronolide B production
S Murli, J Kennedy, LC Dayem, JR Carney, JT Kealey
Journal of Industrial Microbiology and Biotechnology 30 (8), 500-509, 2003
1732003
Functional metagenomic strategies for the discovery of novel enzymes and biosurfactants with biotechnological applications from marine ecosystems
J Kennedy, ND O’Leary, GS Kiran, JP Morrissey, F O’Gara, J Selvin, ...
Journal of applied microbiology 111 (4), 787-799, 2011
1652011
Aspects of the biosynthesis of non-aromatic fungal polyketides by iterative polyketide synthases
CR Hutchinson, J Kennedy, C Park, S Kendrew, K Auclair, J Vederas
Antonie Van Leeuwenhoek 78 (3), 287-295, 2000
1622000
Metagenomic approaches to exploit the biotechnological potential of the microbial consortia of marine sponges
J Kennedy, JR Marchesi, ADW Dobson
Applied microbiology and biotechnology 75 (1), 11-20, 2007
1492007
δ-(L-α-Aminoadipyl)-L-cysteinyl-D-valine synthetase is a rate limiting enzyme for penicillin production in Aspergillus nidulans
J Kennedy, G Turner
Molecular and General Genetics MGG 253 (1), 189-197, 1996
1251996
Diversity of microbes associated with the marine sponge, Haliclona simulans, isolated from Irish waters and identification of polyketide synthase genes from the sponge metagenome
J Kennedy, CE Codling, BV Jones, ADW Dobson, JR Marchesi
Environmental microbiology 10 (7), 1888-1902, 2008
1192008
Isolation identification and biochemical characterization of a novel halo-tolerant lipase from the metagenome of the marine sponge Haliclona simulans
J Selvin, J Kennedy, DPH Lejon, GS Kiran, ADW Dobson
Microb Cell Fact 11 (1), 72, 2012
992012
Diversity and antimicrobial activities of microbes from two Irish marine sponges, Suberites carnosus and Leucosolenia sp.
B Flemer, J Kennedy, LM Margassery, JP Morrissey, F O’Gara, ...
Journal of applied microbiology 112 (2), 289-301, 2012
962012
Pyrosequencing reveals diverse and distinct sponge-specific microbial communities in sponges from a single geographical location in Irish waters
SA Jackson, J Kennedy, JP Morrissey, F O’Gara, ADW Dobson
Microbial ecology 64 (1), 105-116, 2012
872012
Evidence of a putative deep sea specific microbiome in marine sponges
J Kennedy, B Flemer, SA Jackson, JP Morrissey, F O'Gara, ADW Dobson
PloS one 9 (3), e91092, 2014
832014
Phylogenetic diversity and antimicrobial activities of fungi associated with Haliclona simulans isolated from Irish coastal waters
PW Baker, J Kennedy, ADW Dobson, JR Marchesi
Marine Biotechnology 11 (4), 540-547, 2009
822009
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