Ismail Moarefi
Ismail Moarefi
Crelux GmbH
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Crystal structure of the Src family tyrosine kinase Hck
F Sicheri, I Moarefi, J Kuriyan
Nature 385 (6617), 602-609, 1997
Structure of TPR domain–peptide complexes: critical elements in the assembly of the Hsp70–Hsp90 multichaperone machine
C Scheufler, A Brinker, G Bourenkov, S Pegoraro, L Moroder, H Bartunik, ...
Cell 101 (2), 199-210, 2000
Hsp90: a specialized but essential protein-folding tool
JC Young, I Moarefi, FU Hartl
The Journal of cell biology 154 (2), 267-274, 2001
Activation of the Sire-family tyrosine kinase Hck by SH3 domain displacement
I Moarefi, M LaFevre-Bernt, F Sicheri, M Huse, CH Lee, J Kuriyan, ...
Nature 385 (6617), 650-653, 1997
Structure of a Bag/Hsc70 complex: convergent functional evolution of Hsp70 nucleotide exchange factors
H Sondermann, C Scheufler, C Schneider, J Höhfeld, FU Hartl, I Moarefi
Science 291 (5508), 1553-1557, 2001
DNA binding of in vitro activated Stat1 alpha, Stat1 beta and truncated Stat1: interaction between NH2‐terminal domains stabilizes binding of two dimers to tandem DNA sites.
U Vinkemeier, SL Cohen, I Moarefi, BT Chait, J Kuriyan, JE Darnell Jr
The EMBO journal 15 (20), 5616-5626, 1996
Structure of the amino-terminal protein interaction domain of STAT-4
U Vinkemeier, I Moarefi, JE Darnell, J Kuriyan
Science 279 (5353), 1048-1052, 1998
Structure of the molecular chaperone prefoldin: unique interaction of multiple coiled coil tentacles with unfolded proteins
R Siegert, MR Leroux, C Scheufler, FU Hartl, I Moarefi
Cell 103 (4), 621-632, 2000
Ligand discrimination by TPR domains: Relevance and selectivity of EEVD-recognition in Hsp70· Hop· Hsp90 complexes
A Brinker, C Scheufler, F Von der Mülbe, B Fleckenstein, C Herrmann, ...
Journal of Biological Chemistry 277 (22), 19265-19275, 2002
Crystal structure of the DNA polymerase processivity factor of T4 bacteriophage
I Moarefi, D Jeruzalmi, J Turner, M O’Donnell, J Kuriyan
Journal of molecular biology 296 (5), 1215-1223, 2000
Dual-specific Src and Abl kinase inhibitors, PP1 and CGP76030, inhibit growth and survival of cells expressing imatinib mesylate–resistant Bcr-Abl kinases
M Warmuth, N Simon, O Mitina, R Mathes, D Fabbro, PW Manley, ...
Blood, The Journal of the American Society of Hematology 101 (2), 664-672, 2003
The protein import motor of mitochondria: a targeted molecular ratchet driving unfolding and translocation
K Okamoto, A Brinker, SA Paschen, I Moarefi, M Hayer‐Hartl, W Neupert, ...
The EMBO journal 21 (14), 3659-3671, 2002
Structural basis for SH3 domain‐mediated high‐affinity binding between Mona/Gads and SLP‐76
M Harkiolaki, M Lewitzky, RJC Gilbert, EY Jones, RP Bourette, ...
The EMBO journal 22 (11), 2571-2582, 2003
Crystal structure of an archaebacterial DNA polymerase
Y Zhao, D Jeruzalmi, I Moarefi, L Leighton, R Lasken, J Kuriyan
Structure 7 (10), 1189-1199, 1999
Prediction of novel Bag-1 homologs based on structure/function analysis identifies Snl1p as an Hsp70 co-chaperone in Saccharomyces cerevisiae
H Sondermann, AK Ho, LL Listenberger, K Siegers, I Moarefi, SR Wente, ...
Journal of biological chemistry 277 (36), 33220-33227, 2002
T-antigen kinase inhibits simian virus 40 DNA replication by phosphorylation of intact T antigen on serines 120 and 123
A Cegielska, I Moarefi, E Fanning, DM Virshup
Journal of virology 68 (1), 269-275, 1994
Altered phosphorylation pattern of simian virus 40 T antigen expressed in insect cells by using a baculovirus vector
A Höss, I Moarefi, KH Scheidtmann, LJ Cisek, JL Corden, I Dornreiter, ...
Journal of virology 64 (10), 4799-4807, 1990
Mutation of the cyclin-dependent kinase phosphorylation site in simian virus 40 (SV40) large T antigen specifically blocks SV40 origin DNA unwinding
IF Moarefi, D Small, I Gilbert, M Höpfner, SK Randall, C Schneider, ...
Journal of Virology 67 (8), 4992-5002, 1993
Determinants of the in vivo folding of the prion protein: a bipartite function of helix 1 in folding and aggregation
KF Winklhofer, J Heske, U Heller, A Reintjes, W Muranyi, I Moarefi, ...
Journal of Biological Chemistry 278 (17), 14961-14970, 2003
From autoinhibition to inhibition in trans: the Raf-1 regulatory domain inhibits Rok-α kinase activity
T Niault, I Sobczak, K Meissl, G Weitsman, D Piazzolla, G Maurer, F Kern, ...
Journal of Cell Biology 187 (3), 335-342, 2009
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