Functional links between Aβ toxicity, endocytic trafficking, and Alzheimer’s disease risk factors in yeast S Treusch, S Hamamichi, JL Goodman, KES Matlack, CY Chung, V Baru, ... Science 334 (6060), 1241-1245, 2011 | 365 | 2011 |
Caenorhabditis elegans functional orthologue of human protein h-mucolipin-1 is required for lysosome biogenesis S Treusch, S Knuth, SA Slaugenhaupt, E Goldin, BD Grant, H Fares Proceedings of the National Academy of Sciences 101 (13), 4483-4488, 2004 | 227 | 2004 |
Chaperone-dependent amyloid assembly protects cells from prion toxicity PM Douglas*, S Treusch*, HY Ren, R Halfmann, ML Duennwald, ... Proceedings of the National Academy of Sciences 105 (20), 7206, 2008 | 165 | 2008 |
Amyloid deposits: Protection against toxic protein species? S Treusch, DM Cyr, S Lindquist Cell cycle 8 (11), 1668-1674, 2009 | 143 | 2009 |
Genetics of single-cell protein abundance variation in large yeast populations FW Albert, S Treusch, AH Shockley, JS Bloom, L Kruglyak Nature 506 (7489), 494-497, 2014 | 112 | 2014 |
Prion induction involves an ancient system for the sequestration of aggregated proteins and heritable changes in prion fragmentation J Tyedmers, S Treusch, J Dong, JM McCaffery, B Bevis, S Lindquist Proceedings of the National Academy of Sciences 107 (19), 8633, 2010 | 110 | 2010 |
Genetic interactions contribute less than additive effects to quantitative trait variation in yeast JS Bloom, I Kotenko, MJ Sadhu, S Treusch, FW Albert, L Kruglyak Nature communications 6 (1), 1-6, 2015 | 101 | 2015 |
High-throughput single-cell DNA sequencing of acute myeloid leukemia tumors with droplet microfluidics M Pellegrino, A Sciambi, S Treusch, R Durruthy-Durruthy, K Gokhale, ... Genome research 28 (9), 1345-1352, 2018 | 77 | 2018 |
An intrinsically disordered yeast prion arrests the cell cycle by sequestering a spindle pole body component S Treusch, S Lindquist Journal of Cell Biology 197 (3), 369-379, 2012 | 47 | 2012 |
Genetic mapping of MAPK-mediated complex traits across S. cerevisiae S Treusch, FW Albert, JS Bloom, IE Kotenko, L Kruglyak PLoS Genet 11 (1), e1004913, 2015 | 46 | 2015 |
Yeast Cells Expressing Amyloid Beta And Uses Therefor S Treusch, KES Matlack, SL Lindquist, WIFORB RESEARCH US Patent 20,130,045,483, 2013 | 30 | 2013 |
Rare variants contribute disproportionately to quantitative trait variation in yeast JS Bloom, J Boocock, S Treusch, MJ Sadhu, L Day, H Oates-Barker, ... Elife 8, e49212, 2019 | 26 | 2019 |
Compositions and methods for synthetic gene assembly E Toro, S Treusch, S Chen, WU Cheng-Hsien US Patent 9,677,067, 2017 | 24 | 2017 |
Oligonucleic acid variant libraries and synthesis thereof A Cox, S Treusch, S Chen US Patent 10,844,373, 2020 | 22 | 2020 |
Compositions and methods for synthetic gene assembly E Toro, S Treusch, S Chen, WU Cheng-Hsien US Patent App. 15/433,909, 2017 | 22 | 2017 |
Methods for seamless nucleic acid assembly WU Cheng-Hsien, S Treusch US Patent App. 16/712,678, 2020 | 4 | 2020 |
High-throughput single-cell DNA sequencing of AML tumors with droplet microfluidics DJ Eastburn, M Pellegrino, A Sciambi, S Treusch, K Gokhale, J Jacob, ... Blood 130 (Supplement 1), 3965-3965, 2017 | 2 | 2017 |
Yeast cells expressing amyloid beta and uses therefor KES Matlack, SL Lindquist, S Treusch US Patent 9,677,079, 2017 | 1 | 2017 |
Oligonucleic acid variant libraries and synthesis thereof A Cox, S Treusch, S Chen US Patent App. 17/068,551, 2021 | | 2021 |
Methods and compositions for emulsification of solid supports in deformable beads AR Sciambi, DJ Eastburn, S Treusch US Patent App. 16/310,336, 2019 | | 2019 |