Sebastian Treusch
Sebastian Treusch
Associate Director, Mol Bio Ops & NGS
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Functional links between Aβ toxicity, endocytic trafficking, and Alzheimer’s disease risk factors in yeast
S Treusch, S Hamamichi, JL Goodman, KES Matlack, CY Chung, V Baru, ...
Science 334 (6060), 1241-1245, 2011
3652011
Caenorhabditis elegans functional orthologue of human protein h-mucolipin-1 is required for lysosome biogenesis
S Treusch, S Knuth, SA Slaugenhaupt, E Goldin, BD Grant, H Fares
Proceedings of the National Academy of Sciences 101 (13), 4483-4488, 2004
2272004
Chaperone-dependent amyloid assembly protects cells from prion toxicity
PM Douglas*, S Treusch*, HY Ren, R Halfmann, ML Duennwald, ...
Proceedings of the National Academy of Sciences 105 (20), 7206, 2008
1652008
Amyloid deposits: Protection against toxic protein species?
S Treusch, DM Cyr, S Lindquist
Cell cycle 8 (11), 1668-1674, 2009
1432009
Genetics of single-cell protein abundance variation in large yeast populations
FW Albert, S Treusch, AH Shockley, JS Bloom, L Kruglyak
Nature 506 (7489), 494-497, 2014
1122014
Prion induction involves an ancient system for the sequestration of aggregated proteins and heritable changes in prion fragmentation
J Tyedmers, S Treusch, J Dong, JM McCaffery, B Bevis, S Lindquist
Proceedings of the National Academy of Sciences 107 (19), 8633, 2010
1102010
Genetic interactions contribute less than additive effects to quantitative trait variation in yeast
JS Bloom, I Kotenko, MJ Sadhu, S Treusch, FW Albert, L Kruglyak
Nature communications 6 (1), 1-6, 2015
1012015
High-throughput single-cell DNA sequencing of acute myeloid leukemia tumors with droplet microfluidics
M Pellegrino, A Sciambi, S Treusch, R Durruthy-Durruthy, K Gokhale, ...
Genome research 28 (9), 1345-1352, 2018
772018
An intrinsically disordered yeast prion arrests the cell cycle by sequestering a spindle pole body component
S Treusch, S Lindquist
Journal of Cell Biology 197 (3), 369-379, 2012
472012
Genetic mapping of MAPK-mediated complex traits across S. cerevisiae
S Treusch, FW Albert, JS Bloom, IE Kotenko, L Kruglyak
PLoS Genet 11 (1), e1004913, 2015
462015
Yeast Cells Expressing Amyloid Beta And Uses Therefor
S Treusch, KES Matlack, SL Lindquist, WIFORB RESEARCH
US Patent 20,130,045,483, 2013
302013
Rare variants contribute disproportionately to quantitative trait variation in yeast
JS Bloom, J Boocock, S Treusch, MJ Sadhu, L Day, H Oates-Barker, ...
Elife 8, e49212, 2019
262019
Compositions and methods for synthetic gene assembly
E Toro, S Treusch, S Chen, WU Cheng-Hsien
US Patent 9,677,067, 2017
242017
Oligonucleic acid variant libraries and synthesis thereof
A Cox, S Treusch, S Chen
US Patent 10,844,373, 2020
222020
Compositions and methods for synthetic gene assembly
E Toro, S Treusch, S Chen, WU Cheng-Hsien
US Patent App. 15/433,909, 2017
222017
Methods for seamless nucleic acid assembly
WU Cheng-Hsien, S Treusch
US Patent App. 16/712,678, 2020
42020
High-throughput single-cell DNA sequencing of AML tumors with droplet microfluidics
DJ Eastburn, M Pellegrino, A Sciambi, S Treusch, K Gokhale, J Jacob, ...
Blood 130 (Supplement 1), 3965-3965, 2017
22017
Yeast cells expressing amyloid beta and uses therefor
KES Matlack, SL Lindquist, S Treusch
US Patent 9,677,079, 2017
12017
Oligonucleic acid variant libraries and synthesis thereof
A Cox, S Treusch, S Chen
US Patent App. 17/068,551, 2021
2021
Methods and compositions for emulsification of solid supports in deformable beads
AR Sciambi, DJ Eastburn, S Treusch
US Patent App. 16/310,336, 2019
2019
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Artikelen 1–20