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John B. Lees-Shepard
John B. Lees-Shepard
Verified email at uconn.edu
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Cited by
Cited by
Year
Activin-dependent signaling in fibro/adipogenic progenitors causes fibrodysplasia ossificans progressiva
JB Lees-Shepard, M Yamamoto, AA Biswas, SJ Stoessel, SAE Nicholas, ...
Nature communications 9 (1), 471, 2018
1782018
Palovarotene reduces heterotopic ossification in juvenile FOP mice but exhibits pronounced skeletal toxicity
JB Lees-Shepard, SAE Nicholas, SJ Stoessel, PM Devarakonda, ...
Elife 7, e40814, 2018
602018
Activin A forms a non-signaling complex with ACVR1 and type II Activin/BMP receptors via its finger 2 tip loop
S Aykul, RA Corpina, EJ Goebel, CJ Cunanan, A Dimitriou, HJ Kim, ...
Elife 9, e54582, 2020
582020
Stem cells and heterotopic ossification: lessons from animal models
JB Lees-Shepard, DJ Goldhamer
Bone 109, 178-186, 2018
562018
Transient anabolic effects accompany epidermal growth factor receptor signal activation in articular cartilage in vivo
JB Shepard, JW Jeong, NJ Maihle, S O'Brien, CN Dealy
Arthritis research & therapy 15, 1-16, 2013
552013
Versican expression during synovial joint morphogenesis
JB Shepard, HA Krug, BA LaFoon, S Hoffman, AA Capehart
International journal of biological sciences 3 (6), 380, 2007
342007
Anti-ACVR1 antibodies exacerbate heterotopic ossification in fibrodysplasia ossificans progressiva (FOP) by activating FOP-mutant ACVR1
S Aykul, L Huang, L Wang, NM Das, S Reisman, Y Ray, Q Zhang, ...
The Journal of Clinical Investigation 132 (12), 2022
242022
Identification of distinct non-myogenic skeletal-muscle-resident mesenchymal cell populations
AP Leinroth, AJ Mirando, D Rouse, Y Kobayahsi, PR Tata, HE Rueckert, ...
Cell reports 39 (6), 2022
242022
Versican knock‐down compromises chondrogenesis in the embryonic chick limb
JB Shepard, DA Gliga, AP Morrow, S Hoffman, AA Capehart
The Anatomical Record: Advances in Integrative Anatomy and Evolutionary …, 2008
232008
An anti-ACVR1 antibody exacerbates heterotopic ossification by fibro-adipogenic progenitors in fibrodysplasia ossificans progressiva mice
JB Lees-Shepard, SJ Stoessel, JT Chandler, K Bouchard, P Bento, ...
The Journal of Clinical Investigation 132 (12), 2022
192022
FACS fractionation and differentiation of skeletal-muscle resident multipotent Tie2+ progenitors
AA Biswas, DJ Goldhamer
Skeletal Muscle Regeneration in the Mouse: Methods and Protocols, 255-267, 2016
132016
The potential of human embryonic stem cells for articular cartilage repair and osteoarthritis treatment
MC Fisher, D Ferrari, Y Li, JB Shepard, SE Patterson, N Anderson, ...
Rheumatol Curr Res 3, 004, 2012
122012
Overexpression of wild‐type ACVR1 in fibrodysplasia ossificans progressiva mice rescues perinatal lethality and inhibits heterotopic ossification
M Yamamoto, SJ Stoessel, S Yamamoto, DJ Goldhamer
Journal of Bone and Mineral Research 37 (11), 2077-2093, 2020
112020
Activin-dependent signaling in fibro/adipogenic progenitors causes fibrodysplasia ossificans progressiva. Nat Commun 9: 471
JB Lees-Shepard, M Yamamoto, AA Biswas, SJ Stoessel, SAE Nicholas, ...
112018
Cross‐talk between EGFR and BMP signals regulates chondrocyte maturation during endochondral ossification
JB Lees‐Shepard, K Flint, M Fisher, M Omi, K Richard, M Antony, ...
Developmental Dynamics 251 (1), 193-212, 2022
62022
Response to comment on'Palovarotene reduces heterotopic ossification in juvenile FOP mice but exhibits pronounced skeletal toxicity'
DJ Goldhamer, JB Lees-Shepard
Elife 8, e43928, 2019
62019
Twists in the fibrodysplasia ossificans progressiva story challenge and expand our understanding of BMP biology
MT Collins
The Journal of Clinical Investigation 132 (12), 2022
22022
Comment on'Palovarotene reduces heterotopic ossification in juvenile FOP mice but exhibits pronounced skeletal toxicity'
M Pacifici, EM Shore
Elife 8, e43173, 2019
22019
How Activin A Became a Therapeutic Target in Fibrodysplasia Ossificans Progressiva
D Srinivasan, M Arostegui, EJ Goebel, KN Hart, S Aykul, ...
Biomolecules 14 (1), 101, 2024
12024
ACVR1 antibodies exacerbate heterotopic ossification in fibrodysplasia ossificans progressiva (FOP) by activating FOP-mutant ACVR1
S Aykul, L Huang, L Wang, N Das, S Reisman, Y Ray, Q Zhang, ...
bioRxiv, 2021.07. 18.452865, 2021
12021
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