Activin-dependent signaling in fibro/adipogenic progenitors causes fibrodysplasia ossificans progressiva JB Lees-Shepard, M Yamamoto, AA Biswas, SJ Stoessel, SAE Nicholas, ... Nature communications 9 (1), 471, 2018 | 178 | 2018 |
Palovarotene reduces heterotopic ossification in juvenile FOP mice but exhibits pronounced skeletal toxicity JB Lees-Shepard, SAE Nicholas, SJ Stoessel, PM Devarakonda, ... Elife 7, e40814, 2018 | 60 | 2018 |
Activin A forms a non-signaling complex with ACVR1 and type II Activin/BMP receptors via its finger 2 tip loop S Aykul, RA Corpina, EJ Goebel, CJ Cunanan, A Dimitriou, HJ Kim, ... Elife 9, e54582, 2020 | 58 | 2020 |
Stem cells and heterotopic ossification: lessons from animal models JB Lees-Shepard, DJ Goldhamer Bone 109, 178-186, 2018 | 56 | 2018 |
Transient anabolic effects accompany epidermal growth factor receptor signal activation in articular cartilage in vivo JB Shepard, JW Jeong, NJ Maihle, S O'Brien, CN Dealy Arthritis research & therapy 15, 1-16, 2013 | 55 | 2013 |
Versican expression during synovial joint morphogenesis JB Shepard, HA Krug, BA LaFoon, S Hoffman, AA Capehart International journal of biological sciences 3 (6), 380, 2007 | 34 | 2007 |
Anti-ACVR1 antibodies exacerbate heterotopic ossification in fibrodysplasia ossificans progressiva (FOP) by activating FOP-mutant ACVR1 S Aykul, L Huang, L Wang, NM Das, S Reisman, Y Ray, Q Zhang, ... The Journal of Clinical Investigation 132 (12), 2022 | 24 | 2022 |
Identification of distinct non-myogenic skeletal-muscle-resident mesenchymal cell populations AP Leinroth, AJ Mirando, D Rouse, Y Kobayahsi, PR Tata, HE Rueckert, ... Cell reports 39 (6), 2022 | 24 | 2022 |
Versican knock‐down compromises chondrogenesis in the embryonic chick limb JB Shepard, DA Gliga, AP Morrow, S Hoffman, AA Capehart The Anatomical Record: Advances in Integrative Anatomy and Evolutionary …, 2008 | 23 | 2008 |
An anti-ACVR1 antibody exacerbates heterotopic ossification by fibro-adipogenic progenitors in fibrodysplasia ossificans progressiva mice JB Lees-Shepard, SJ Stoessel, JT Chandler, K Bouchard, P Bento, ... The Journal of Clinical Investigation 132 (12), 2022 | 19 | 2022 |
FACS fractionation and differentiation of skeletal-muscle resident multipotent Tie2+ progenitors AA Biswas, DJ Goldhamer Skeletal Muscle Regeneration in the Mouse: Methods and Protocols, 255-267, 2016 | 13 | 2016 |
The potential of human embryonic stem cells for articular cartilage repair and osteoarthritis treatment MC Fisher, D Ferrari, Y Li, JB Shepard, SE Patterson, N Anderson, ... Rheumatol Curr Res 3, 004, 2012 | 12 | 2012 |
Overexpression of wild‐type ACVR1 in fibrodysplasia ossificans progressiva mice rescues perinatal lethality and inhibits heterotopic ossification M Yamamoto, SJ Stoessel, S Yamamoto, DJ Goldhamer Journal of Bone and Mineral Research 37 (11), 2077-2093, 2020 | 11 | 2020 |
Activin-dependent signaling in fibro/adipogenic progenitors causes fibrodysplasia ossificans progressiva. Nat Commun 9: 471 JB Lees-Shepard, M Yamamoto, AA Biswas, SJ Stoessel, SAE Nicholas, ... | 11 | 2018 |
Cross‐talk between EGFR and BMP signals regulates chondrocyte maturation during endochondral ossification JB Lees‐Shepard, K Flint, M Fisher, M Omi, K Richard, M Antony, ... Developmental Dynamics 251 (1), 193-212, 2022 | 6 | 2022 |
Response to comment on'Palovarotene reduces heterotopic ossification in juvenile FOP mice but exhibits pronounced skeletal toxicity' DJ Goldhamer, JB Lees-Shepard Elife 8, e43928, 2019 | 6 | 2019 |
Twists in the fibrodysplasia ossificans progressiva story challenge and expand our understanding of BMP biology MT Collins The Journal of Clinical Investigation 132 (12), 2022 | 2 | 2022 |
Comment on'Palovarotene reduces heterotopic ossification in juvenile FOP mice but exhibits pronounced skeletal toxicity' M Pacifici, EM Shore Elife 8, e43173, 2019 | 2 | 2019 |
How Activin A Became a Therapeutic Target in Fibrodysplasia Ossificans Progressiva D Srinivasan, M Arostegui, EJ Goebel, KN Hart, S Aykul, ... Biomolecules 14 (1), 101, 2024 | 1 | 2024 |
ACVR1 antibodies exacerbate heterotopic ossification in fibrodysplasia ossificans progressiva (FOP) by activating FOP-mutant ACVR1 S Aykul, L Huang, L Wang, N Das, S Reisman, Y Ray, Q Zhang, ... bioRxiv, 2021.07. 18.452865, 2021 | 1 | 2021 |