Inclusion bodies: specificity in their aggregation process and amyloid-like structure M Morell, R Bravo, A Espargaró, X Sisquella, FX Avilés, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1783 (10), 1815-1825, 2008 | 157 | 2008 |
Detection of transient protein–protein interactions by bimolecular fluorescence complementation: The Abl‐SH3 case M Morell, A Espargaró, FX Avilés, S Ventura Proteomics 7 (7), 1023-1036, 2007 | 126 | 2007 |
Bacterial Inclusion Bodies of Alzheimer's Disease β‐Amyloid Peptides Can Be Employed To Study Native‐Like Aggregation Intermediate States M Dasari, A Espargaro, R Sabate, JM Lopez del Amo, U Fink, G Grelle, ... ChemBioChem 12 (3), 407-423, 2011 | 107 | 2011 |
Study and selection of in vivo protein interactions by coupling bimolecular fluorescence complementation and flow cytometry M Morell, A Espargaro, FX Aviles, S Ventura Nature protocols 3 (1), 22-33, 2008 | 91 | 2008 |
Magnetic nanoparticles cross the blood-brain barrier: when physics rises to a challenge MA Busquets, A Espargaró, R Sabaté, J Estelrich Nanomaterials 5 (4), 2231-2248, 2015 | 84 | 2015 |
Combined in vitro cell-based/in silico screening of naturally occurring flavonoids and phenolic compounds as potential anti-Alzheimer drugs A Espargaró, T Ginex, MM Vadell, MA Busquets, J Estelrich, ... Journal of natural products 80 (2), 278-289, 2017 | 83 | 2017 |
Novel levetiracetam derivatives that are effective against the Alzheimer-like phenotype in mice: synthesis, in vitro, ex vivo, and in vivo efficacy studies I Sola, E Aso, D Frattini, I Lopez-Gonzalez, A Espargaro, R Sabate, ... Journal of medicinal chemistry 58 (15), 6018-6032, 2015 | 70 | 2015 |
Tetrahydrobenzo [h][1, 6] naphthyridine-6-chlorotacrine hybrids as a new family of anti-Alzheimer agents targeting β-amyloid, tau, and cholinesterase pathologies O Di Pietro, FJ Pérez-Areales, J Juárez-Jiménez, A Espargaro, MV Clos, ... European Journal of Medicinal Chemistry 84, 107-117, 2014 | 68 | 2014 |
Natural Xanthones from Garcinia mangostana with Multifunctional Activities for the Therapy of Alzheimer’s Disease S Wang, Q Li, M Jing, E Alba, X Yang, R Sabaté, Y Han, R Pi, W Lan, ... Neurochemical research 41, 1806-1817, 2016 | 67 | 2016 |
The in vivo and in vitro aggregation properties of globular proteins correlate with their conformational stability: the SH3 case A Espargaró, V Castillo, NS de Groot, S Ventura Journal of molecular biology 378 (5), 1116-1131, 2008 | 66 | 2008 |
Thioflavin-S staining coupled to flow cytometry. A screening tool to detect in vivo protein aggregation A Espargaró, R Sabate, S Ventura Molecular BioSystems 8 (11), 2839-2844, 2012 | 61 | 2012 |
Discovery of novel inhibitors of amyloid β-peptide 1–42 aggregation LC López, S Dos-Reis, A Espargaró, JA Carrodeguas, ML Maddelein, ... Journal of Medicinal Chemistry 55 (22), 9521-9530, 2012 | 58 | 2012 |
Shogaol–huprine hybrids: dual antioxidant and anticholinesterase agents with β-amyloid and tau anti-aggregating properties FJ Pérez-Areales, O Di Pietro, A Espargaró, A Vallverdú-Queralt, ... Bioorganic & Medicinal Chemistry 22 (19), 5298-5307, 2014 | 57 | 2014 |
Ultra rapid in vivo screening for anti-Alzheimer anti-amyloid drugs A Espargaró, A Medina, O Di Pietro, D Muñoz-Torrero, R Sabate Scientific Reports 6 (1), 23349, 2016 | 52 | 2016 |
Characterization of the amyloid bacterial inclusion bodies of the HET-s fungal prion R Sabaté, A Espargaró, SJ Saupe, S Ventura Microbial cell factories 8, 1-10, 2009 | 52 | 2009 |
On the binding of Congo red to amyloid fibrils A Espargaró, S Llabrés, SJ Saupe, C Curutchet, FJ Luque, R Sabaté Angewandte Chemie 132 (21), 8181-8184, 2020 | 51 | 2020 |
Thioflavin-S staining of bacterial inclusion bodies for the fast, simple, and inexpensive screening of amyloid aggregation inhibitors S Pouplana, A Espargaro, C Galdeano, E Viayna, I Sola, S Ventura, ... Current Medicinal Chemistry 21 (9), 1152-1159, 2014 | 51 | 2014 |
Design, synthesis and multitarget biological profiling of second-generation anti-Alzheimer rhein–huprine hybrids FJ Pérez-Areales, N Betari, A Viayna, C Pont, A Espargaró, M Bartolini, ... Future Medicinal Chemistry 9 (10), 965-981, 2017 | 50 | 2017 |
The role of protein sequence and amino acid composition in amyloid formation: scrambling and backward reading of IAPP amyloid fibrils R Sabaté, A Espargaró, NS de Groot, JJ Valle-Delgado, ... Journal of molecular biology 404 (2), 337-352, 2010 | 48 | 2010 |
Effect of the surface charge of artificial model membranes on the aggregation of amyloid β-peptide R Sabaté, A Espargaró, L Barbosa-Barros, S Ventura, J Estelrich Biochimie 94 (8), 1730-1738, 2012 | 45 | 2012 |