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Oliver Wicht
Oliver Wicht
Verified email at rivm.nl - Homepage
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Coronavirus cell entry occurs through the endo-/lysosomal pathway in a proteolysis-dependent manner
C Burkard, MH Verheije, O Wicht, SI van Kasteren, FJ van Kuppeveld, ...
PLoS pathogens 10 (11), e1004502, 2014
4302014
Proteolytic activation of the porcine epidemic diarrhea coronavirus spike fusion protein by trypsin in cell culture
O Wicht, W Li, L Willems, TJ Meuleman, RW Wubbolts, ...
Journal of virology 88 (14), 7952-7961, 2014
1462014
Structural and functional analysis of hepatitis C virus strain JFH1 polymerase
P Simister, M Schmitt, M Geitmann, O Wicht, UH Danielson, R Klein, ...
Journal of virology 83 (22), 11926-11939, 2009
1062009
Manipulation of the porcine epidemic diarrhea virus genome using targeted RNA recombination
C Li, Z Li, Y Zou, O Wicht, FJM van Kuppeveld, PJM Rottier, BJ Bosch
PLoS One 8 (8), e69997, 2013
842013
A comprehensive structure-function comparison of hepatitis C virus strain JFH1 and J6 polymerases reveals a key residue stimulating replication in cell culture across genotypes
M Schmitt, N Scrima, D Radujkovic, C Caillet-Saguy, PC Simister, ...
Journal of virology 85 (6), 2565-2581, 2011
782011
Characterization of Epitope-Specific Anti-Respiratory Syncytial Virus Antibody Responses after Natural Infection and after Vaccination with Formalin-Inactivated RSV
I Widjaja, O Wicht, W Luytjes, K Leenhouts, PJM Rottier, ...
Journal of Virology 90 (13), 5965-5977, 2016
532016
Phosphorylation-dependent feedback inhibition of RIG-I by DAPK1 identified by kinome-wide siRNA screening
J Willemsen, O Wicht, JC Wolanski, N Baur, S Bastian, DA Haas, P Matula, ...
Molecular cell 65 (3), 403-415. e8, 2017
512017
A single point mutation creating a furin cleavage site in the spike protein renders porcine epidemic diarrhea coronavirus trypsin independent for cell entry and fusion
W Li, O Wicht, FJM van Kuppeveld, Q He, PJM Rottier, BJ Bosch
Journal of virology 89 (15), 8077-8081, 2015
412015
Identification and characterization of a proteolytically primed form of the murine coronavirus spike proteins after fusion with the target cell
O Wicht, C Burkard, CAM de Haan, FJM van Kuppeveld, PJM Rottier, ...
Journal of virology 88 (9), 4943-4952, 2014
372014
Characteristics of RSV-specific maternal antibodies in plasma of hospitalized, acute RSV patients under three months of age
J Jans, O Wicht, I Widjaja, IML Ahout, R de Groot, T Guichelaar, W Luytjes, ...
PloS one 12 (1), e0170877, 2017
342017
Respiratory syncytial virus infects primary neonatal and adult natural killer cells and affects their antiviral effector function
EA van Erp, D Feyaerts, M Duijst, HL Mulder, O Wicht, W Luytjes, ...
The Journal of Infectious Diseases 219 (5), 723-733, 2019
272019
In Vitro Enhancement of Respiratory Syncytial Virus Infection by Maternal Antibodies Does Not Explain Disease Severity in Infants
EA van Erp, PB van Kasteren, T Guichelaar, IML Ahout, CAM de Haan, ...
Journal of virology 91 (21), 10.1128/jvi. 00851-17, 2017
262017
RSV neutralization by palivizumab, but not by monoclonal antibodies targeting other epitopes, is augmented by Fc gamma receptors
L van Mechelen, W Luytjes, CAM de Haan, O Wicht
Antiviral Research 132, 1-5, 2016
202016
Dissecting virus entry: replication-independent analysis of virus binding, internalization, and penetration using minimal complementation of β-galactosidase
C Burkard, LM Bloyet, O Wicht, FJ Van Kuppeveld, PJM Rottier, ...
PloS one 9 (7), e101762, 2014
202014
A single point mutation creating a furin cleavage site in the spike protein renders porcine epidemic diarrhea coronavirus trypsin independent for cell entry and fusion.
LWT Li WenTao, O Wicht, FJM Kuppeveld, HQG He QiGai, PJM Rottier, ...
12015
Proteolytic Activation of the Coronavirus Fusion Protein
O Wicht
Utrecht University, 2014
12014
In vitro enhancement of RSV infection by maternal antibodies does not explain disease severity in infants
EA van Erp, PB van Kasteren, T Guichelaar, IML Ahout, CAM de Haan, ...
Journal of Virology 91 (21), 2017
2017
Characterization of epitope-specific anti-RSV antibody responses after natural infection and after vaccination with formalin-inactivated RSV. 2
I Widjaja, O Wicht, W Luytjes, K Leenhouts, PJM Rottier, ...
Journal of Virology 90 (13), 5965-5977, 2016
2016
Manipulation of the porcine epidemic diarrhea virus genome using targeted RNA recombination.
LCH Li ChunHua, LZ Li Zhen, ZY Zou Yong, O Wicht, FJM Kuppeveld, ...
2013
Complex Requirements for Hyperphosphorylation of Hepatitis C Virus NS5A
M Schmitt, N Scrima, D Radujkovic, C Caillet-Saguy, PC Simister, ...
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