Aaron E. Lin
Aaron E. Lin
Postdoctoral fellow, Princeton University
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SARS-CoV-2 disrupts splicing, translation, and protein trafficking to suppress host defenses
AK Banerjee, MR Blanco, EA Bruce, DD Honson, LM Chen, A Chow, ...
Cell 183 (5), 1325-1339. e21, 2020
Zika virus evolution and spread in the Americas
HC Metsky, CB Matranga, S Wohl, SF Schaffner, CA Freije, SM Winnicki, ...
Nature 546 (7658), 411-415, 2017
Programmable inhibition and detection of RNA viruses using Cas13
CA Freije, C Myhrvold, CK Boehm, AE Lin, NL Welch, A Carter, ...
Molecular cell 76 (5), 826-837. e11, 2019
Ebola virus epidemiology, transmission, and evolution during seven months in Sierra Leone
DJ Park, G Dudas, S Wohl, A Goba, SLM Whitmer, KG Andersen, ...
Cell 161 (7), 1516-1526, 2015
Phylogenetic analysis of SARS-CoV-2 in Boston highlights the impact of superspreading events
JE Lemieux, KJ Siddle, BM Shaw, C Loreth, SF Schaffner, ...
Science 371 (6529), eabe3261, 2021
Clinical sequencing uncovers origins and evolution of Lassa virus
KG Andersen, BJ Shapiro, CB Matranga, R Sealfon, AE Lin, LM Moses, ...
Cell 162 (4), 738-750, 2015
Ebola virus glycoprotein with increased infectivity dominated the 2013–2016 epidemic
WE Diehl*, AE Lin*, ND Grubaugh*, LM Carvalho*, K Kim, PP Kyawe, ...
Cell 167 (4), 1088-1098. e6, 2016
Deployable CRISPR-Cas13a diagnostic tools to detect and report Ebola and Lassa virus cases in real-time
KG Barnes, AE Lachenauer, A Nitido, S Siddiqui, R Gross, B Beitzel, ...
Nature communications 11 (1), 4131, 2020
Capturing sequence diversity in metagenomes with comprehensive and scalable probe design
HC Metsky, KJ Siddle, A Gladden-Young, J Qu, DK Yang, P Brehio, ...
Nature biotechnology 37 (2), 160-168, 2019
Structural basis of specificity and cross-reactivity in T cell receptors specific for cytochrome c–I-Ek
EW Newell, LK Ely, AC Kruse, PA Reay, SN Rodriguez, AE Lin, MS Kuhns, ...
The Journal of Immunology 186 (10), 5823-5832, 2011
Single-cell profiling of Ebola virus disease in vivo reveals viral and host dynamics
D Kotliar*, AE Lin*, J Logue, TK Hughes, NM Khoury, SS Raju, ...
Cell 183 (5), 1383-1401. e19, 2020
In vivo Ebola virus infection leads to a strong innate response in circulating immune cells
IS Caballero, AN Honko, SK Gire, SM Winnicki, M Melé, C Gerhardinger, ...
BMC genomics 17, 1-13, 2016
Evaluation of the potential impact of Ebola virus genomic drift on the efficacy of sequence-based candidate therapeutics
JR Kugelman, M Sanchez-Lockhart, KG Andersen, S Gire, DJ Park, ...
MBio 6 (1), 10.1128/mbio. 02227-14, 2015
Field validation of recombinant antigen immunoassays for diagnosis of Lassa fever
ML Boisen, JN Hartnett, JG Shaffer, A Goba, M Momoh, JD Sandi, ...
Scientific reports 8 (1), 5939, 2018
A proteomic perspective of inbuilt viral protein regulation: pUL46 tegument protein is targeted for degradation by ICP0 during herpes simplex virus type 1 infection
AE Lin, TM Greco, K Döhner, B Sodeik, IM Cristea
Molecular & Cellular Proteomics 12 (11), 3237-3252, 2013
Evidence of Ebola virus replication and high concentration in semen of a patient during recovery
KG Barnes*, J Kindrachuk*, AE Lin*, S Wohl, J Qu, SD Tostenson, ...
Clinical Infectious Diseases 65 (8), 1400-1403, 2017
DNA methyltransferase DNMT3A associates with viral proteins and impacts HSV‐1 infection
DL Rowles, YC Tsai, TM Greco, AE Lin, M Li, J Yeh, IM Cristea
Proteomics 15 (12), 1968-1982, 2015
Reporter assays for Ebola virus nucleoprotein oligomerization, virion-like particle budding, and minigenome activity reveal the importance of nucleoprotein amino acid position 111
AE Lin*, WE Diehl*, Y Cai, CL Finch, C Akusobi, RN Kirchdoerfer, ...
Viruses 12 (1), 105, 2020
Single-cell massively-parallel multiplexed microbial sequencing (M3-seq) identifies rare bacterial populations and profiles phage infection
B Wang, AE Lin, J Yuan, KE Novak, MD Koch, NS Wingreen, B Adamson, ...
Nature Microbiology 8 (10), 1846-1862, 2023
Single-cell profiling of lncRNA expression during Ebola virus infection in rhesus macaques
L Santus, M Sopena-Rios, R García-Pérez, AE Lin, GC Adams, ...
Nature Communications 14 (1), 3866, 2023
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