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Ronny Drapkin, MD, PhD
Ronny Drapkin, MD, PhD
University of Pennsylvania, Perelman School of Medicine
Geverifieerd e-mailadres voor pennmedicine.upenn.edu - Homepage
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Dicer-deficient mouse embryonic stem cells are defective in differentiation and centromeric silencing
C Kanellopoulou, SA Muljo, AL Kung, S Ganesan, R Drapkin, T Jenuwein, ...
Genes & development 19 (4), 489-501, 2005
15962005
Rethinking ovarian cancer: recommendations for improving outcomes
S Vaughan, JI Coward, RC Bast Jr, A Berchuck, JS Berek, JD Brenton, ...
Nature Reviews Cancer 11 (10), 719-725, 2011
14822011
Whole–genome characterization of chemoresistant ovarian cancer
AM Patch, EL Christie, D Etemadmoghadam, DW Garsed, J George, ...
Nature 521 (7553), 489-494, 2015
14672015
Rethinking ovarian cancer II: reducing mortality from high-grade serous ovarian cancer
DD Bowtell, S Böhm, AA Ahmed, PJ Aspuria, RC Bast Jr, V Beral, ...
Nature reviews Cancer 15 (11), 668-679, 2015
11182015
A candidate precursor to serous carcinoma that originates in the distal fallopian tube
Y Lee, A Miron, R Drapkin, MR Nucci, F Medeiros, A Saleemuddin, ...
The Journal of Pathology: A Journal of the Pathological Society of Great …, 2007
10592007
53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers
P Bouwman, A Aly, JM Escandell, M Pieterse, J Bartkova, ...
Nature structural & molecular biology 17 (6), 688-695, 2010
10502010
Human epididymis protein 4 (HE4) is a secreted glycoprotein that is overexpressed by serous and endometrioid ovarian carcinomas
R Drapkin, HH Von Horsten, Y Lin, SC Mok, CP Crum, WR Welch, ...
Cancer research 65 (6), 2162-2169, 2005
9182005
The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by the COP9 signalosome in response to DNA damage
R Groisman, J Polanowska, I Kuraoka, J Sawada, M Saijo, R Drapkin, ...
Cell 113 (3), 357-367, 2003
8852003
BACH1, a novel helicase-like protein, interacts directly with BRCA1 and contributes to its DNA repair function
SB Cantor, DW Bell, S Ganesan, EM Kass, R Drapkin, S Grossman, ...
Cell 105 (1), 149-160, 2001
8502001
High grade serous ovarian carcinomas originate in the fallopian tube
SI Labidi-Galy, E Papp, D Hallberg, N Niknafs, V Adleff, M Noe, ...
Nature communications 8 (1), 1093, 2017
6632017
Prognostically relevant gene signatures of high-grade serous ovarian carcinoma
RGW Verhaak, P Tamayo, JY Yang, D Hubbard, H Zhang, CJ Creighton, ...
The Journal of clinical investigation 123 (1), 2012
6412012
Pretreatment mitochondrial priming correlates with clinical response to cytotoxic chemotherapy
TN Chonghaile, KA Sarosiek, TT Vo, JA Ryan, A Tammareddi, ...
Science 334 (6059), 1129-1133, 2011
6282011
The distal fallopian tube: a new model for pelvic serous carcinogenesis
CP Crum, R Drapkin, A Miron, TA Ince, M Muto, DW Kindelberger, Y Lee
Current Opinion in Obstetrics and Gynecology 19 (1), 3-9, 2007
6022007
Transformation of the fallopian tube secretory epithelium leads to high-grade serous ovarian cancer in Brca; Tp53; Pten models
R Perets, GA Wyant, KW Muto, JG Bijron, BB Poole, KT Chin, JYH Chen, ...
Cancer cell 24 (6), 751-765, 2013
6012013
Dual role of TFIIH in DNA excision repair and in transcription by RNA polymerase II
R Drapkin, JT Reardon, A Ansari, JC Huang, L Zawel, KJ Ahn, A Sancar, ...
Nature 368 (6473), 769-772, 1994
5941994
A recurrent mutation in PALB2 in Finnish cancer families
H Erkko, B Xia, J Nikkilä, J Schleutker, K Syrjäkoski, A Mannermaa, ...
Nature 446 (7133), 316-319, 2007
5572007
Cdk-activating kinase complex is a component of human transcription factor TFIIH
R Shiekhattar, F Mermelstein, RP Fisher, R Drapkin, B Dynlacht, ...
Nature 374 (6519), 283-287, 1995
5451995
New insights into the pathogenesis of serous ovarian cancer and its clinical impact
K Levanon, C Crum, R Drapkin
Journal of Clinical Oncology 26 (32), 5284, 2008
5072008
Systematic investigation of genetic vulnerabilities across cancer cell lines reveals lineage-specific dependencies in ovarian cancer
HW Cheung, GS Cowley, BA Weir, JS Boehm, S Rusin, JA Scott, A East, ...
Proceedings of the National Academy of Sciences 108 (30), 12372-12377, 2011
5002011
A human RNA polymerase II complex associated with SRB and DNA-repair proteins
E Maldonado, R Shiekhattar, M Sheldon, H Cho, R Drapkin, P Rickert, ...
Nature 381 (6577), 86-89, 1996
4751996
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