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F. Brad Johnson, MD, PhD
F. Brad Johnson, MD, PhD
Professor of Pathology and Laboratory Medicine
Geverifieerd e-mailadres voor pennmedicine.upenn.edu
Titel
Geciteerd door
Geciteerd door
Jaar
Determinants of response and resistance to CD19 chimeric antigen receptor (CAR) T cell therapy of chronic lymphocytic leukemia
JA Fraietta, SF Lacey, EJ Orlando, I Pruteanu-Malinici, M Gohil, S Lundh, ...
Nature medicine 24 (5), 563-571, 2018
13352018
Histone H4 lysine 16 acetylation regulates cellular lifespan
W Dang, KK Steffen, R Perry, JA Dorsey, FB Johnson, A Shilatifard, ...
Nature 459 (7248), 802-807, 2009
7252009
Molecular biology of aging
FB Johnson, DA Sinclair, L Guarente
Cell 96 (2), 291-302, 1999
7101999
Astrocyte senescence as a component of Alzheimer’s disease
R Bhat, EP Crowe, A Bitto, M Moh, CD Katsetos, FU Garcia, FB Johnson, ...
Public Library of Science 7 (9), e45069, 2012
5352012
Detection of G-quadruplex DNA in mammalian cells
A Henderson, Y Wu, YC Huang, EA Chavez, J Platt, FB Johnson, ...
Nucleic acids research 42 (2), 860-869, 2013
4892013
Genomic distribution and functional analyses of potential G-quadruplex-forming sequences in Saccharomyces cerevisiae
SG Hershman, Q Chen, JY Lee, ML Kozak, P Yue, LS Wang, FB Johnson
Nucleic acids research 36 (1), 144-156, 2008
3352008
The Saccharomyces cerevisiae WRN homolog Sgs1p participates in telomere maintenance in cells lacking telomerase
FB Johnson, RA Marciniak, M McVey, SA Stewart, WC Hahn, L Guarente
The EMBO journal 20 (4), 905-913, 2001
3312001
Identification of chimeric antigen receptors that mediate constitutive or inducible proliferation of T cells
MJ Frigault, J Lee, MC Basil, C Carpenito, S Motohashi, J Scholler, ...
Cancer immunology research 3 (4), 356-367, 2015
3092015
Dysregulation of the epigenetic landscape of normal aging in Alzheimer’s disease
R Nativio, G Donahue, A Berson, Y Lan, A Amlie-Wolf, F Tuzer, JB Toledo, ...
Nature neuroscience 21 (4), 497-505, 2018
2782018
Telomere shortening exposes functions for the mouse Werner and Bloom syndrome genes
X Du, J Shen, N Kugan, EE Furth, DB Lombard, C Cheung, S Pak, G Luo, ...
Molecular and cellular biology 24 (19), 8437-8446, 2004
2562004
DNA-damage-induced type I interferon promotes senescence and inhibits stem cell function
Q Yu, YV Katlinskaya, CJ Carbone, B Zhao, KV Katlinski, H Zheng, ...
Cell reports 11 (5), 785-797, 2015
2412015
Nucleolar localization of the Werner syndrome protein in human cells
RA Marciniak, DB Lombard, FB Johnson, L Guarente
Proceedings of the National Academy of Sciences 95 (12), 6887-6892, 1998
2391998
Sir2: an NAD-dependent histone deacetylase that connects chromatin silencing, metabolism, and aging
S Imai, FB Johnson, RA Marciniak, M McVey, PU Park, L Guarente
Cold Spring Harbor symposia on quantitative biology 65, 297-302, 2000
1992000
SLC25A51 is a mammalian mitochondrial NAD+ transporter
TS Luongo, JM Eller, MJ Lu, M Niere, F Raith, C Perry, MR Bornstein, ...
Nature 588 (7836), 174-179, 2020
1942020
Role for G-quadruplex RNA binding by Epstein-Barr virus nuclear antigen 1 in DNA replication and metaphase chromosome attachment
J Norseen, FB Johnson, PM Lieberman
Journal of virology 83 (20), 10336-10346, 2009
1892009
Association of the Bloom syndrome protein with topoisomerase IIIα in somatic and meiotic cells
FB Johnson, DB Lombard, NF Neff, MA Mastrangelo, W Dewolf, NA Ellis, ...
Cancer research 60 (5), 1162-1167, 2000
1862000
Altered gene expression in the Werner and Bloom syndromes is associated with sequences having G-quadruplex forming potential
JE Johnson, K Cao, P Ryvkin, LS Wang, FB Johnson
Nucleic acids research 38 (4), 1114-1122, 2010
1642010
Defects in telomere maintenance molecules impair osteoblast differentiation and promote osteoporosis
RJ Pignolo, RK Suda, EA McMillan, J Shen, SH Lee, Y Choi, AC Wright, ...
Aging cell 7 (1), 23-31, 2008
1572008
Rudimentary G-quadruplex–based telomere capping in Saccharomyces cerevisiae
JS Smith, Q Chen, LA Yatsunyk, JM Nicoludis, MS Garcia, R Kranaster, ...
Nature structural & molecular biology 18 (4), 478-485, 2011
1562011
HMGB2 orchestrates the chromatin landscape of senescence-associated secretory phenotype gene loci
KM Aird, O Iwasaki, AV Kossenkov, H Tanizawa, N Fatkhutdinov, BG Bitler, ...
Journal of Cell Biology 215 (3), 325-334, 2016
1532016
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