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Rachel Rigby
Rachel Rigby
Exscientia
Geverifieerd e-mailadres voor exscientia.co.uk
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Finishing the euchromatic sequence of the human genome
International Human Genome Sequencing Consortium
Nature 431 (7011), 931-945, 2004
51842004
Enzymatic removal of ribonucleotides from DNA is essential for mammalian genome integrity and development
MAM Reijns, B Rabe, RE Rigby, P Mill, KR Astell, LA Lettice, S Boyle, ...
Cell 149 (5), 1008-1022, 2012
5062012
Ribonuclease H2 mutations induce a cGAS/STING‐dependent innate immune response
KJ Mackenzie, P Carroll, L Lettice, Ž Tarnauskaitė, K Reddy, F Dix, ...
The EMBO journal 35 (8), 831-844, 2016
2372016
Accurate and reliable high-throughput detection of copy number variation in the human genome
H Fiegler, R Redon, D Andrews, C Scott, R Andrews, C Carder, R Clark, ...
Genome research 16 (12), 1566-1574, 2006
1852006
Nitro-fatty acids are formed in response to virus infection and are potent inhibitors of STING palmitoylation and signaling
AL Hansen, GJ Buchan, M Rühl, K Mukai, SR Salvatore, E Ogawa, ...
Proceedings of the National Academy of Sciences 115 (33), E7768-E7775, 2018
1782018
RNA: DNA hybrids are a novel molecular pattern sensed by TLR 9
RE Rigby, LM Webb, KJ Mackenzie, Y Li, A Leitch, MAM Reijns, ...
The EMBO journal 33 (6), 542-558, 2014
1722014
SAMHD1‐dependent retroviral control and escape in mice
J Rehwinkel, J Maelfait, A Bridgeman, R Rigby, B Hayward, RA Liberatore, ...
The EMBO journal 32 (18), 2454-2462, 2013
1592013
Mammalian mitochondrial DNA replication intermediates are essentially duplex but contain extensive tracts of RNA/DNA hybrid
JLO Pohjoismäki, JB Holmes, SR Wood, MY Yang, T Yasukawa, A Reyes, ...
Journal of molecular biology 397 (5), 1144-1155, 2010
1502010
Infection with a Brazilian isolate of Zika virus generates RIG‐I stimulatory RNA and the viral NS5 protein blocks type I IFN induction and signaling
J Hertzog, AG Dias Junior, RE Rigby, CL Donald, A Mayer, E Sezgin, ...
European journal of immunology 48 (7), 1120-1136, 2018
1372018
RNA degradation in antiviral immunity and autoimmunity
RE Rigby, J Rehwinkel
Trends in immunology 36 (3), 179-188, 2015
852015
Adenosine-to-inosine editing of endogenous Z-form RNA by the deaminase ADAR1 prevents spontaneous MAVS-dependent type I interferon responses
Q Tang, RE Rigby, GR Young, AK Hvidt, T Davis, TK Tan, A Bridgeman, ...
Immunity 54 (9), 1961-1975. e5, 2021
732021
Nucleic acid‐mediated inflammatory diseases
RE Rigby, A Leitch, AP Jackson
Bioessays 30 (9), 833-842, 2008
512008
Multi-modal characterization of monocytes in idiopathic pulmonary fibrosis reveals a primed type I interferon immune phenotype
E Fraser, L Denney, A Antanaviciute, K Blirando, C Vuppusetty, Y Zheng, ...
Frontiers in Immunology 12, 623430, 2021
412021
Varicella‐Zoster virus ORF9 is an antagonist of the DNA sensor cGAS
J Hertzog, W Zhou, G Fowler, RE Rigby, A Bridgeman, HTW Blest, C Cursi, ...
The EMBO journal 41 (14), e109217, 2022
292022
PA-X antagonises MAVS-dependent accumulation of early type I interferon messenger RNAs during influenza A virus infection
RE Rigby, HM Wise, N Smith, P Digard, J Rehwinkel
Scientific reports 9 (1), 7216, 2019
282019
Deoxyguanosine is a TLR7 agonist
T Davenne, A Bridgeman, RE Rigby, J Rehwinkel
European journal of immunology 50 (1), 56-62, 2020
252020
SAMHD1 limits the efficacy of forodesine in leukemia by protecting cells against the cytotoxicity of dGTP
T Davenne, J Klintman, S Sharma, RE Rigby, HTW Blest, C Cursi, ...
Cell reports 31 (6), 2020
212020
Fractional response analysis reveals logarithmic cytokine responses in cellular populations
K Nienałtowski, RE Rigby, J Walczak, KE Zakrzewska, E Głów, ...
Nature Communications 12 (1), 4175, 2021
82021
Recognition of Z-RNA by ADAR1 limits interferon responses
Q Tang, RE Rigby, GR Young, A Korning-Hvidt, TK Tan, A Bridgeman, ...
bioRxiv, 2020.12. 04.411793, 2020
52020
Typ-1-Interferonopathien
V Tüngler, M Lee-Kirsch
Arthritis und Rheuma 34 (04), 225-233, 2014
32014
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