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Gizem Karsli Uzunbas
Gizem Karsli Uzunbas
Research Scientist at Broad Institute
Geverifieerd e-mailadres voor dfci.harvard.edu
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Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis
JY Guo, HY Chen, R Mathew, J Fan, AM Strohecker, G Karsli-Uzunbas, ...
Genes & development 25 (5), 460-470, 2011
14392011
Autophagy suppresses progression of K-ras-induced lung tumors to oncocytomas and maintains lipid homeostasis
JY Guo, G Karsli-Uzunbas, R Mathew, SC Aisner, JJ Kamphorst, ...
Genes & development 27 (13), 1447-1461, 2013
6032013
Autophagy is required for glucose homeostasis and lung tumor maintenance
G Karsli-Uzunbas, JY Guo, S Price, X Teng, SV Laddha, S Khor, ...
Cancer discovery 4 (8), 914-927, 2014
5252014
Autophagy Sustains Mitochondrial Glutamine Metabolism and Growth of BrafV600E–Driven Lung Tumors
AM Strohecker, JY Guo, G Karsli-Uzunbas, SM Price, GJ Chen, R Mathew, ...
Cancer discovery 3 (11), 1272-1285, 2013
4582013
Autophagy promotes mammalian survival by suppressing oxidative stress and p53
Y Yang, G Karsli-Uzunbas, L Poillet-Perez, A Sawant, ZS Hu, Y Zhao, ...
Genes & development 34 (9-10), 688-700, 2020
772020
Elevated p62/SQSTM1 determines the fate of autophagy-deficient neural stem cells by increasing superoxide
C Wang, S Chen, S Yeo, G Karsli-Uzunbas, E White, N Mizushima, ...
Journal of Cell Biology 212 (5), 545-560, 2016
642016
Autophagy is required for glucose homeostasis and lung tumor maintenance. Cancer Discov. 2014; 4: 914–27. doi: 10.1158/2159-8290
G Karsli-Uzunbas, JY Guo, S Price, X Teng, SV Laddha, S Khor, ...
CD-14-0363, 0
40
Pramanicin analog induces apoptosis in human colon cancer cells: critical roles for Bcl-2, Bim, and p38 MAPK signaling
C Bodur, O Kutuk, G Karsli-Uzunbas, TT Isimjan, P Harrison, H Basaga
PLoS One 8 (2), e56369, 2013
322013
Control of p53-dependent transcription and enhancer activity by the p53 family member p63
GK Uzunbas, F Ahmed, MA Sammons
Journal of Biological Chemistry 294 (27), 10720-10736, 2019
292019
Locally acting transcription factors regulate p53-dependent cis-regulatory element activity
AN Catizone, GK Uzunbas, P Celadova, S Kuang, D Bose, MA Sammons
Nucleic Acids Research 48 (8), 4195-4213, 2020
152020
Preclinical activity of the first reversible, potent and selective inhibitor of EGFR exon 20 insertions
F Siegel, S Siegel, K Graham, B Kaplan, K Petersen, U Boemer, ...
Cancer Research 81 (13_Supplement), 1470-1470, 2021
62021
BAY 2927088: The first non-covalent, potent, and selective tyrosine kinase inhibitor targeting EGFR exon 20 insertions and C797S resistance mutations in NSCLC
F Siegel, S Siegel, K Graham, G Karsli-Uzunbas, D Korr, J Schroeder, ...
European Journal of Cancer 174, S9-S10, 2022
42022
Preclinical activity of BAY 2927088 in HER2 mutant non-small cell lung cancer
F Siegel, G Karsli-Uzunbas, K Kotynkova, Q McVeigh, S Siegel, D Korr, ...
Cancer Research 83 (7_Supplement), 4035-4035, 2023
22023
Cell type-dependent control of p53 transcription and enhancer activity by p63
GK Uzunbas, F Ahmed, MA Sammons
bioRxiv, 268649, 2018
22018
Stromal autophagy is required for the growth of cutaneous melanoma
RE Zhang, NJ Guo, N Krishnan, D Jelinek, GK Uzunbas, X Xie, A Gertych, ...
Cancer Research 76 (14_Supplement), 4081-4081, 2016
2016
Elevated p62/SQSTM1 determines the fate of autophagy-deficient neural stem cells by increasing superoxide (vol 212, pg 545, 2016)
C Wang, S Chen, S Yeo, G Karsli-Uzunbas, E White, N Mizushima, ...
JOURNAL OF CELL BIOLOGY 212 (7), 879-879, 2016
2016
Autophagy in tissue homeostasis and cancer
G Karsli Uzunbas
Rutgers University-Graduate School-New Brunswick, 2015
2015
Research Communications
W Hu, B Yuan, J Flygare, HF Lodish, T Shimi, V Butin-Israeli, SA Adam, ...
GENES & DEVELOPMENT, 2011
2011
Future Table of Contents
SE Polo, SP Jackson, DR Burrill, PA Silver, EG Folco, KE Coil, R Reed, ...
Genes & Development 25, 2011
2011
JCB: Correction
C Wang, S Chen, S Yeo, G Karsli-Uzunbas, E White, N Mizushima, ...
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Artikelen 1–20