Carl Virtanen
Carl Virtanen
Senior Director Research and IT Operations, UHN Digital; Associate Director HPC4Health
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DNA methylation profiles in monozygotic and dizygotic twins
ZA Kaminsky, T Tang, SC Wang, C Ptak, GHT Oh, AHC Wong, ...
Nature genetics 41 (2), 240-245, 2009
IDH1 (R132H) mutation increases murine haematopoietic progenitors and alters epigenetics
M Sasaki, CB Knobbe, JC Munger, EF Lind, D Brenner, A Brüstle, ...
Nature 488 (7413), 656-659, 2012
AACR Project GENIE: powering precision medicine through an international consortium
AACR Project Genie Consortium
Cancer discovery 7 (8), 818-831, 2017
Microarray-based DNA methylation profiling: technology and applications
A Schumacher, P Kapranov, Z Kaminsky, J Flanagan, A Assadzadeh, ...
Nucleic acids research 34 (2), 528-542, 2006
Functional genomic landscape of human breast cancer drivers, vulnerabilities, and resistance
R Marcotte, A Sayad, KR Brown, F Sanchez-Garcia, J Reimand, M Haider, ...
Cell 164 (1-2), 293-309, 2016
Intra-and interindividual epigenetic variation in human germ cells
JM Flanagan, V Popendikyte, N Pozdniakovaite, M Sobolev, ...
The American Journal of Human Genetics 79 (1), 67-84, 2006
Two prognostically significant subtypes of high-grade lung neuroendocrine tumours independent of small-cell and large-cell neuroendocrine carcinomas identified by gene …
MH Jones, C Virtanen, D Honjoh, T Miyoshi, Y Satoh, S Okumura, ...
The Lancet 363 (9411), 775-781, 2004
Molecular profiling of advanced solid tumors and patient outcomes with genotype-matched clinical trials: the Princess Margaret IMPACT/COMPACT trial
TL Stockley, AM Oza, HK Berman, NB Leighl, JJ Knox, FA Shepherd, ...
Genome medicine 8 (1), 1-12, 2016
Integrated classification of lung tumors and cell lines by expression profiling
C Virtanen, Y Ishikawa, D Honjoh, M Kimura, M Shimane, T Miyoshi, ...
Proceedings of the National Academy of Sciences 99 (19), 12357-12362, 2002
Global proteomic assessment of the classical protein-tyrosine phosphatome and “Redoxome”
R Karisch, M Fernandez, P Taylor, C Virtanen, JR St-Germain, LL Jin, ...
Cell 146 (5), 826-840, 2011
Three-dimensional culture and cAMP signaling promote the maturation of human pluripotent stem cell-derived hepatocytes
S Ogawa, J Surapisitchat, C Virtanen, M Ogawa, M Niapour, KS Sugamori, ...
Development 140 (15), 3285-3296, 2013
Two subclasses of lung squamous cell carcinoma with different gene expression profiles and prognosis identified by hierarchical clustering and non-negative matrix factorization
K Inamura, T Fujiwara, Y Hoshida, T Isagawa, MH Jones, C Virtanen, ...
Oncogene 24 (47), 7105-7113, 2005
The NF-κB regulator MALT1 determines the encephalitogenic potential of Th17 cells
A Brüstle, D Brenner, CB Knobbe, PA Lang, C Virtanen, BM Hershenfield, ...
The Journal of clinical investigation 122 (12), 4698-4709, 2012
Low malignant potential tumors with micropapillary features are molecularly similar to low-grade serous carcinoma of the ovary
T May, C Virtanen, M Sharma, A Milea, H Begley, B Rosen, KJ Murphy, ...
Gynecologic oncology 117 (1), 9-17, 2010
Microarray analysis of the infrapatellar fat pad in knee osteoarthritis: relationship with joint inflammation
R Gandhi, M Takahashi, C Virtanen, K Syed, JR Davey, NN Mahomed
The Journal of rheumatology 38 (9), 1966-1972, 2011
MicroRNA expression profiling of esophageal cancer before and after induction chemoradiotherapy
MA Ko, G Zehong, C Virtanen, M Guindi, TK Waddell, S Keshavjee, ...
The Annals of thoracic surgery 94 (4), 1094-1103, 2012
PTP1B controls non-mitochondrial oxygen consumption by regulating RNF213 to promote tumour survival during hypoxia
RS Banh, C Iorio, R Marcotte, Y Xu, D Cojocari, AA Rahman, J Pawling, ...
Nature cell biology 18 (7), 803-813, 2016
Activating mutations affecting the Dbl homology domain of SOS2 cause Noonan syndrome
V Cordeddu, JC Yin, C Gunnarsson, C Virtanen, S Drunat, F Lepri, ...
Human mutation 36 (11), 1080-1087, 2015
Plasminogen activator uPA is a direct transcriptional target of the JAG1-Notch receptor signaling pathway in breast cancer
M Shimizu, B Cohen, P Goldvasser, H Berman, C Virtanen, M Reedijk
Cancer research 71 (1), 277-286, 2011
In Vivo Optical Imaging of Tumor and Microvascular Response to Ionizing Radiation
A Maeda, MKK Leung, L Conroy, Y Chen, J Bu, PE Lindsay, S Mintzberg, ...
Public Library of Science 7 (8), e42133, 2012
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