Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis GM DeNicola, FA Karreth, TJ Humpton, A Gopinathan, C Wei, K Frese, ... Nature 475 (7354), 106-109, 2011 | 2387 | 2011 |
Coding-independent regulation of the tumor suppressor PTEN by competing endogenous mRNAs Y Tay, L Kats, L Salmena, D Weiss, SM Tan, U Ala, F Karreth, L Poliseno, ... Cell 147 (2), 344-357, 2011 | 1125 | 2011 |
ceRNA cross-talk in cancer: when ce-bling rivalries go awry FA Karreth, PP Pandolfi Cancer discovery 3 (10), 1113-1121, 2013 | 821* | 2013 |
In vivo identification of tumor-suppressive PTEN ceRNAs in an oncogenic BRAF-induced mouse model of melanoma FA Karreth, Y Tay, D Perna, U Ala, SM Tan, AG Rust, G DeNicola, ... Cell 147 (2), 382-395, 2011 | 744 | 2011 |
Integrated transcriptional and competitive endogenous RNA networks are cross-regulated in permissive molecular environments U Ala, FA Karreth, C Bosia, A Pagnani, R Taulli, V Léopold, Y Tay, ... Proceedings of the National Academy of Sciences 110 (18), 7154-7159, 2013 | 344 | 2013 |
The BRAF pseudogene functions as a competitive endogenous RNA and induces lymphoma in vivo FA Karreth, M Reschke, A Ruocco, C Ng, B Chapuy, V Léopold, ... Cell 161 (2), 319-332, 2015 | 338 | 2015 |
Demonstration of a genetic therapeutic index for tumors expressing oncogenic BRAF by the kinase inhibitor SB-590885 AJ King, DR Patrick, RS Batorsky, ML Ho, HT Do, SY Zhang, R Kumar, ... Cancer research 66 (23), 11100-11105, 2006 | 306 | 2006 |
Mice lacking JunB are osteopenic due to cell-autonomous osteoblast and osteoclast defects L Kenner, A Hoebertz, FT Beil, N Keon, F Karreth, R Eferl, H Scheuch, ... The Journal of cell biology 164 (4), 613-623, 2004 | 247 | 2004 |
Platelet-released supernatants increase migration and proliferation, and decrease osteogenic differentiation of bone marrow-derived mesenchymal progenitor cells under in vitro … R Gruber, F Karreth, B Kandler, G Fuerst, A Rot, MB Fischer, G Watzek Platelets 15 (1), 29-35, 2004 | 245 | 2004 |
The Fos‐related antigen Fra‐1 is an activator of bone matrix formation R Eferl, A Hoebertz, AF Schilling, M Rath, F Karreth, L Kenner, M Amling, ... The EMBO journal 23 (14), 2789-2799, 2004 | 241 | 2004 |
Germline Brca2 heterozygosity promotes KrasG12D-driven carcinogenesis in a murine model of familial pancreatic cancer F Skoulidis, LD Cassidy, V Pisupati, JG Jonasson, H Bjarnason, ... Cancer cell 18 (5), 499-509, 2010 | 186 | 2010 |
BRAF inhibitor resistance mediated by the AKT pathway in an oncogenic BRAF mouse melanoma model D Perna, FA Karreth, AG Rust, PA Perez-Mancera, M Rashid, F Iorio, ... Proceedings of the National Academy of Sciences 112 (6), E536-E545, 2015 | 163 | 2015 |
C-Raf Is Required for the Initiation of Lung Cancer by K-RasG12D FA Karreth, KK Frese, GM DeNicola, M Baccarini, DA Tuveson Cancer discovery 1 (2), 128-136, 2011 | 156 | 2011 |
Melanoma models for the next generation of therapies EE Patton, KL Mueller, DJ Adams, N Anandasabapathy, AE Aplin, ... Cancer cell 39 (5), 610-631, 2021 | 148 | 2021 |
Twist induces an epithelial-mesenchymal transition to facilitate tumor metastasis F Karreth, DA Tuveson Cancer biology & therapy 3 (11), 1058-1059, 2004 | 134 | 2004 |
JunD regulates lymphocyte proliferation and T helper cell cytokine expression A Meixner, F Karreth, L Kenner, EF Wagner The EMBO journal 23 (6), 1325-1335, 2004 | 133 | 2004 |
Platelets are mitogenic for periosteum‐derived cells R Gruber, F Karreth, F Frommlet, MB Fischer, G Watzek Journal of Orthopaedic Research 21 (5), 941-948, 2003 | 125 | 2003 |
The AP1 transcription factor Fra2 is required for efficient cartilage development F Karreth, A Hoebertz, H Scheuch, R Eferl, EF Wagner Oxford University Press for The Company of Biologists Limited 131 (22), 5717 …, 2004 | 109 | 2004 |
Cathepsin B promotes the progression of pancreatic ductal adenocarcinoma in mice A Gopinathan, GM DeNicola, KK Frese, N Cook, FA Karreth, J Mayerle, ... Gut 61 (6), 877-884, 2012 | 89 | 2012 |
Platelet-released supernatants stimulate formation of osteoclast-like cells through a prostaglandin/RANKL-dependent mechanism R Gruber, F Karreth, MB Fischer, G Watzek Bone 30 (5), 726-732, 2002 | 87 | 2002 |